Wilma van de Berg

PhD, (Principal Investigator)

20002024

Research activity per year

Personal profile

specialisation

Wilma van de Berg is senior translational and cellular neuroscientist, principal investigator and associate professor at dept. Anatomy and Neurosciences, head of the research section Clinical Neuroanatomy and Biobanking (CNAB), member of executive board of Advanced Optical Microscopy Core (www.ao2m.amsterdam) and lecturer in clinical neuroanatomy, neuropathology of movement disorders and clinical and translational neurosciences, Amsterdam UMC.  She is an expert in human neuroanatomy, morphometry and 3D imaging (quantitaive MRI-to-pathology), and structural and cellular biology. She is founder and director of the Normal Aging Brain Bank (www.nabca.eu), which collects advanced postmortem MRI and high-quality brain tissue of non-demented elderly for stimulating translational research in neurosciences. 

 

Research interests

Her research over the years has focused on unravelling cellular mechanisms underpinning selective vulnerability, protein aggregation, clinical heterogeneity and disease progression in Parkinson’s disease and related neurodegenerative disorders. The knowledge on neuroanatomy, neuropathology, cellular disease mechanisms and human brain morphology in aging and disease is utilized to define novel MRI and biofluid biomarkers for improving early diagnosis and prediction of cognitive decline in Parkinson’s disease. She has gained experience in conducting clinical studies (e.g. PROGRESS-PD) in which Parkinson patients and age-matched controls were followed for eight years and identification of biofluid markers for disease progression in PD. She currently co-leads the longitudinal cohort ‘Profiling Parkinson’s’(ProPARK) and works closely together with clinical and industrie partners to identify molecular subtypes in Parkinson's disease. She is also partner in a large EU consortium, named NEUROCOV, which aims to unravel wich cell types are susceptible to SARS-CoV-2 infection and how damage occurs and what makes individualss vulnerable or resistant to such complications. 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 9 - Industry, Innovation, and Infrastructure

Education/Academic qualification

PhD, Cellular Neuroscience and Pediatrics, Maastricht University

Award Date: 12 Jun 2003

Master, Biological Health Sciences, Maastricht University, Maastricht, Netherlands

1 Sept 199330 Sept 2030

Award Date: 30 Sept 1998

External positions

President of Dutch Parkinson Scientists Association, Dutch Parkinson Scientists

1 Apr 20211 Apr 2024

Executive Board Parkinsonalliance Netherlands, Parkinsonalliance Netherlands

26 Mar 202126 Mar 2025

Keywords

  • QD Chemistry
  • Biochemistry
  • RB Pathology
  • morphometry
  • QM Human anatomy
  • MRI
  • cellular imaging
  • RZ Other systems of medicine
  • Neurology
  • Molecular Biology
  • molecular diagnostics

Collaborations and top research areas from the last five years

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