Synthesis and initial preclinical evaluation of the P2X(7) receptor antagonist [C-11]A-740003 as a novel tracer of neuroinflammation

B. Janssen, D.J. Vugts, U. Funke, A. Spaans, R.C. Schuit, E. Kooijman, M. Rongen, L.R. Perk, A.A. Lammertsma, A.D. Windhorst

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Neuroinflammation, in particular activation of microglia, is thought to play an important role in the progression of neurodegenerative diseases. In activated microglia, the purinergic P2X
Original languageEnglish
Pages (from-to)509-516
JournalJournal of Labelled Compounds and Radiopharmaceuticals
Issue number8
Publication statusPublished - 2014

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