TY - JOUR
T1 - The association between metabolic syndrome, obesity-related outcomes, and ADHD in adults with comorbid affective disorders
AU - Wynchank, Dora
AU - Bijlenga, Denise
AU - Lamers, Femke
AU - Kooij, J. J.Sandra
AU - Bron, Tannetje I.
AU - Beekman, Aartjan T.F.
AU - Penninx, Brenda W.J.H.
PY - 2018/3/1
Y1 - 2018/3/1
N2 - Objective: ADHD may predispose to obesity, a metabolic syndrome component. Affective disorders are also associated with MetSyn and ADHD. This study examined whether ADHD confers any added risk of MetSyn and obesity-related associations in a large sample with varying stages of affective disorders. Method: Participants included 2,303 adults from the Netherlands Study of Depression and Anxiety. Three groups were compared (controls, those with depressive/anxiety disorders without ADHD; and those with depressive/anxiety disorders and ADHD) for presence of MetSyn risk factors, body mass index, and waist–hip ratio. ADHD symptoms were identified by using a T-score > 65 (Conners Adult ADHD Rating Scale). Results: Multivariable analyses were additionally adjusted for sociodemographic, lifestyle, health factors, and affective disorders. Analyses showed no significant association between MetSyn, obesity-related variables, and comorbid ADHD. High Inattention and Hyperactivity/Impulsivity symptoms were not associated with MetSyn. Conclusion: This study did not confirm that MetSyn and obesity-related parameters are increased in comorbid ADHD.
AB - Objective: ADHD may predispose to obesity, a metabolic syndrome component. Affective disorders are also associated with MetSyn and ADHD. This study examined whether ADHD confers any added risk of MetSyn and obesity-related associations in a large sample with varying stages of affective disorders. Method: Participants included 2,303 adults from the Netherlands Study of Depression and Anxiety. Three groups were compared (controls, those with depressive/anxiety disorders without ADHD; and those with depressive/anxiety disorders and ADHD) for presence of MetSyn risk factors, body mass index, and waist–hip ratio. ADHD symptoms were identified by using a T-score > 65 (Conners Adult ADHD Rating Scale). Results: Multivariable analyses were additionally adjusted for sociodemographic, lifestyle, health factors, and affective disorders. Analyses showed no significant association between MetSyn, obesity-related variables, and comorbid ADHD. High Inattention and Hyperactivity/Impulsivity symptoms were not associated with MetSyn. Conclusion: This study did not confirm that MetSyn and obesity-related parameters are increased in comorbid ADHD.
KW - ADHD
KW - anxiety
KW - depression
KW - metabolic syndrome
UR - http://www.scopus.com/inward/record.url?scp=85046776786&partnerID=8YFLogxK
U2 - https://doi.org/10.1177/1087054716659137
DO - https://doi.org/10.1177/1087054716659137
M3 - Article
C2 - 27422611
SN - 1087-0547
VL - 22
SP - 460
EP - 471
JO - Journal of Attention Disorders
JF - Journal of Attention Disorders
IS - 5
ER -