The contact activation proteins: a structure/function overview

J. C. Meijers, B. A. McMullen, B. N. Bouma

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Abstract

In recent years, extensive knowledge has been obtained on the structure/function relationships of blood coagulation proteins. In this overview, we present recent developments on the structure/function relationships of the contact activation proteins: factor XII, high molecular weight kininogen, prekallikrein, and factor XI, with the emphasis on the localization of domains on these proteins that are involved in the interaction with activators, substrates and cofactors
Original languageEnglish
Pages (from-to)219-230
JournalAgents and actions. Supplements
Volume38 ( Pt 2)
Publication statusPublished - 1992

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