The histone minority report: The variant shall not be silenced

Fred van Leeuwen, Daniel E. Gottschling

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)

Abstract

In this issue of Cell, Meneghini et al. demonstrate that replacement of canonical histone H2A with the histone variant H2A.Z within euchromatin prevents silent chromatin proteins from migrating into regions of the chromosome that normally are transcriptionally active. Thus, this highly conserved histone variant is critical for defining chromatin domains.
Original languageEnglish
Pages (from-to)591-593
JournalCell
Volume112
Issue number5
DOIs
Publication statusPublished - 2003
Externally publishedYes

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