The interaction between anticoagulant protein S and complement regulatory C4b-binding protein (C4BP)

R. H. van de Poel; J. C. Meijers; B. N. Bouma

doi:https://doi.org/10.1016/S1050-1738(00)00051-7

The interaction between anticoagulant protein S and complement regulatory C4b-binding protein (C4BP)

R. H. van de Poel, J. C. Meijers, B. N. Bouma

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Research output: Contribution to journal › Article › Academic › peer-review

9 Citations (Scopus)

Abstract

An important mechanism of regulation of blood coagulation is the anticoagulant protein C pathway. In this pathway, the anticoagulant activity of activated protein C is increased by its cofactor protein S. The cofactor activity of protein S can be regulated by binding to complement regulatory C4b-binding protein (C4BP). The sites of interaction of protein S and C4BP are discussed

Original language	English
Pages (from-to)	71-76
Journal	Trends in cardiovascular medicine
Volume	10
Issue number	2
DOIs	https://doi.org/10.1016/S1050-1738(00)00051-7
Publication status	Published - 2000

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https://doi.org/10.1016/S1050-1738(00)00051-7

Cite this

@article{229e08f2898c4d29b71fac87be0dd441,

title = "The interaction between anticoagulant protein S and complement regulatory C4b-binding protein (C4BP)",

abstract = "An important mechanism of regulation of blood coagulation is the anticoagulant protein C pathway. In this pathway, the anticoagulant activity of activated protein C is increased by its cofactor protein S. The cofactor activity of protein S can be regulated by binding to complement regulatory C4b-binding protein (C4BP). The sites of interaction of protein S and C4BP are discussed",

author = "{van de Poel}, {R. H.} and Meijers, {J. C.} and Bouma, {B. N.}",

year = "2000",

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AU - van de Poel, R. H.

AU - Meijers, J. C.

AU - Bouma, B. N.

PY - 2000

Y1 - 2000

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AB - An important mechanism of regulation of blood coagulation is the anticoagulant protein C pathway. In this pathway, the anticoagulant activity of activated protein C is increased by its cofactor protein S. The cofactor activity of protein S can be regulated by binding to complement regulatory C4b-binding protein (C4BP). The sites of interaction of protein S and C4BP are discussed

U2 - https://doi.org/10.1016/S1050-1738(00)00051-7

DO - https://doi.org/10.1016/S1050-1738(00)00051-7

M3 - Article

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SN - 1050-1738

VL - 10

SP - 71

EP - 76

JO - Trends in cardiovascular medicine

JF - Trends in cardiovascular medicine

IS - 2

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