Tumor immune escape in acute myeloid leukemia: Class II-associated invariant chain peptide expression as result of deficient antigen presentation

Marvin M. van Luijn; Martine E. D. Chamuleau; Gert J. Ossenkoppele; Arjan A. van de Loosdrecht; S. Marieke van Ham

doi:https://doi.org/10.4161/onci.1.2.18100

Tumor immune escape in acute myeloid leukemia: Class II-associated invariant chain peptide expression as result of deficient antigen presentation

Marvin M. van Luijn, Martine E. D. Chamuleau, Gert J. Ossenkoppele, Arjan A. van de Loosdrecht, S. Marieke van Ham

Research output: Contribution to journal › Editorial › Academic › peer-review

8 Citations (Scopus)

Abstract

In this overview, we discuss the role of class II-associated invariant chain peptide (CLIP) in acute myeloid leukemia (AML), one of the few tumors expressing HLA class II. The clinical impact, function and regulation of CLIP expression on leukemic cells is addressed, indicating its potential as immunotherapeutic target in AML

Original language	English
Pages (from-to)	211-213
Journal	Oncoimmunology
Volume	1
Issue number	2
DOIs	https://doi.org/10.4161/onci.1.2.18100
Publication status	Published - 2012

Access to Document

https://doi.org/10.4161/onci.1.2.18100

Cite this

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title = "Tumor immune escape in acute myeloid leukemia: Class II-associated invariant chain peptide expression as result of deficient antigen presentation",

abstract = "In this overview, we discuss the role of class II-associated invariant chain peptide (CLIP) in acute myeloid leukemia (AML), one of the few tumors expressing HLA class II. The clinical impact, function and regulation of CLIP expression on leukemic cells is addressed, indicating its potential as immunotherapeutic target in AML",

author = "{van Luijn}, {Marvin M.} and Chamuleau, {Martine E. D.} and Ossenkoppele, {Gert J.} and {van de Loosdrecht}, {Arjan A.} and {van Ham}, {S. Marieke}",

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AU - van Luijn, Marvin M.

AU - Chamuleau, Martine E. D.

AU - Ossenkoppele, Gert J.

AU - van de Loosdrecht, Arjan A.

AU - van Ham, S. Marieke

PY - 2012

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AB - In this overview, we discuss the role of class II-associated invariant chain peptide (CLIP) in acute myeloid leukemia (AML), one of the few tumors expressing HLA class II. The clinical impact, function and regulation of CLIP expression on leukemic cells is addressed, indicating its potential as immunotherapeutic target in AML

U2 - https://doi.org/10.4161/onci.1.2.18100

DO - https://doi.org/10.4161/onci.1.2.18100

M3 - Editorial

C2 - 22720245

SN - 2162-4011

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JO - OncoImmunology

JF - OncoImmunology

IS - 2

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