TY - JOUR
T1 - Ultrasonography, computed tomography and magnetic resonance imaging for diagnosis and determining resectability of pancreatic adenocarcinoma - A meta-analysis
AU - Bipat, Shandra
AU - Phoa, Saffire S. K. S.
AU - van Delden, Otto M.
AU - Bossuyt, Patrick M. M.
AU - Gouma, Dirk J.
AU - Laméris, Johan S.
AU - Stoker, Jaap
PY - 2005
Y1 - 2005
N2 - Objective: To compare ultrasonography (US), computed tomography (CT), and magnetic resonance imaging (MRI) in the diagnosis and determination of resectability of pancreatic adenocarcinoma. Methods: Articles reporting US, CT, or MRI data of patients with known or suspected pancreatic adenocarcinoma and at least 20 patients verified with histopathology, surgical findings, or follow-up were included. A bivariate random effects approach was used to calculate sensitivity and specificity for diagnosis and resectability of pancreatic adenocarcinoma. Results: Sixty-eight articles fulfilled all inclusion criteria. For diagnosis, sensitivities of helical CT, conventional CT, MRI, and US were 91%, 86%, 84%, and 76% and specificities were 85%, 79%, 82%, and 75% respectively. Sensitivities for MRI and US were significantly lower compared with helical CT (P = 0.04 and P = 0.0001). For determining resectability, sensitivities of helical CT, conventional CT, MRI, and US were 81%, 82%, 82, and 83% and specificities were 82%, 76%, 78%, and 63% respectively. Specificity of US was significantly lower compared with helical CT (P = 0.011). Conclusions: Helical CT is preferable as an imaging modality for the diagnosis and determination of resectability of pancreatic adenocarcinoma
AB - Objective: To compare ultrasonography (US), computed tomography (CT), and magnetic resonance imaging (MRI) in the diagnosis and determination of resectability of pancreatic adenocarcinoma. Methods: Articles reporting US, CT, or MRI data of patients with known or suspected pancreatic adenocarcinoma and at least 20 patients verified with histopathology, surgical findings, or follow-up were included. A bivariate random effects approach was used to calculate sensitivity and specificity for diagnosis and resectability of pancreatic adenocarcinoma. Results: Sixty-eight articles fulfilled all inclusion criteria. For diagnosis, sensitivities of helical CT, conventional CT, MRI, and US were 91%, 86%, 84%, and 76% and specificities were 85%, 79%, 82%, and 75% respectively. Sensitivities for MRI and US were significantly lower compared with helical CT (P = 0.04 and P = 0.0001). For determining resectability, sensitivities of helical CT, conventional CT, MRI, and US were 81%, 82%, 82, and 83% and specificities were 82%, 76%, 78%, and 63% respectively. Specificity of US was significantly lower compared with helical CT (P = 0.011). Conclusions: Helical CT is preferable as an imaging modality for the diagnosis and determination of resectability of pancreatic adenocarcinoma
U2 - https://doi.org/10.1097/01.rct.0000164513.23407.b3
DO - https://doi.org/10.1097/01.rct.0000164513.23407.b3
M3 - Article
C2 - 16012297
SN - 0363-8715
VL - 29
SP - 438
EP - 445
JO - Journal of Computer Assisted Tomography
JF - Journal of Computer Assisted Tomography
IS - 4
ER -