TY - JOUR
T1 - Unusual complication after immediate postoperative intravesical Mitomycin C instillation
AU - Nieuwenhuijzen, Jakko A.
AU - Bex, Axel
AU - Horenblas, Simon
PY - 2003/6/1
Y1 - 2003/6/1
N2 - Immediate adjuvant Mitomycin C (MMC) instillation is routine practice in the treatment of superficial bladder cancer. Despite relative safety we describe a case of MMC extravasation after intravesical instillation. This resulted in severe continuous pain in the pelvic region without tendency of spontaneous healing, and required surgical debridement. To assess perivesical soft tissue injury prior to surgery MRI imaging turned out to be more accurate than computer tomography. Suggestions about how to avoid, diagnose and treat this symptomatic extravasation are made. © 2003 Elsevier Science B.V. All rights reserved.
AB - Immediate adjuvant Mitomycin C (MMC) instillation is routine practice in the treatment of superficial bladder cancer. Despite relative safety we describe a case of MMC extravasation after intravesical instillation. This resulted in severe continuous pain in the pelvic region without tendency of spontaneous healing, and required surgical debridement. To assess perivesical soft tissue injury prior to surgery MRI imaging turned out to be more accurate than computer tomography. Suggestions about how to avoid, diagnose and treat this symptomatic extravasation are made. © 2003 Elsevier Science B.V. All rights reserved.
KW - Complications
KW - Extravasation
KW - Intravesical chemotherapeutics
KW - Intravesical mitomycin C
KW - Superficial bladder cancer
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0038700511&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/12767376
UR - http://www.scopus.com/inward/record.url?scp=0038700511&partnerID=8YFLogxK
U2 - https://doi.org/10.1016/S0302-2838(03)00151-9
DO - https://doi.org/10.1016/S0302-2838(03)00151-9
M3 - Article
C2 - 12767376
SN - 0302-2838
VL - 43
SP - 711
EP - 712
JO - European Urology
JF - European Urology
IS - 6
ER -