TY - JOUR
T1 - Vocal cord dysfunction in amyotrophic lateral sclerosis: four cases and a review of the literature
AU - van der Graaff, Maaike M.
AU - Grolman, Wilko
AU - Westermann, Erik J.
AU - Boogaardt, Hans C.
AU - Koelman, Hans
AU - van der Kooi, Anneke J.
AU - Tijssen, Marina A.
AU - de Visser, Marianne
PY - 2009
Y1 - 2009
N2 - We describe 4 patients with amyotrophic lateral sclerosis (ALS) and glottic narrowing due to vocal cord dysfunction, and review the literature found using the following search terms: amyotrophic lateral sclerosis, motor neuron disease, stridor, laryngospasm, vocal cord abductor paresis, and hoarseness. Neurological literature rarely reports vocal cord dysfunction in ALS, in contrast to otolaryngology literature (4%-30% of patients with ALS). Both infranuclear and supranuclear mechanisms may play a role. Vocal cord dysfunction can occur at any stage of disease and may account for sudden death in ALS. Treatment of severe cases includes acute airway management and tracheotomy
AB - We describe 4 patients with amyotrophic lateral sclerosis (ALS) and glottic narrowing due to vocal cord dysfunction, and review the literature found using the following search terms: amyotrophic lateral sclerosis, motor neuron disease, stridor, laryngospasm, vocal cord abductor paresis, and hoarseness. Neurological literature rarely reports vocal cord dysfunction in ALS, in contrast to otolaryngology literature (4%-30% of patients with ALS). Both infranuclear and supranuclear mechanisms may play a role. Vocal cord dysfunction can occur at any stage of disease and may account for sudden death in ALS. Treatment of severe cases includes acute airway management and tracheotomy
U2 - https://doi.org/10.1001/archneurol.2009.250
DO - https://doi.org/10.1001/archneurol.2009.250
M3 - Review article
C2 - 19901163
SN - 0003-9942
VL - 66
SP - 1329
EP - 1333
JO - Archives of neurology
JF - Archives of neurology
IS - 11
ER -