TY - JOUR
T1 - Xenon - Edelgas mit organprotektiven Eigenschaften
AU - Preckel, B.
AU - Weber, N.
AU - Schlack, W.
PY - 2004
Y1 - 2004
N2 - Besides it's anaesthetic properties, xenon may induce biological effects that may protect various organs from ischaemia-reperfusion injury. Xenon is an antagonist of the NMDA-receptor and reduces the neuronal injury mediated via these receptors. In contrast to other NMDA-receptor antagonists, xenon has no neurotoxic side effects. Xenon also protects the heart in ischaemia-reperfusion situations. Xenon reduces the post-ischaemic reperfusion injury and offers cardioprotection by inducing pharmacological preconditioning. These organ protective properties of xenon might be useful in special clinical situations
AB - Besides it's anaesthetic properties, xenon may induce biological effects that may protect various organs from ischaemia-reperfusion injury. Xenon is an antagonist of the NMDA-receptor and reduces the neuronal injury mediated via these receptors. In contrast to other NMDA-receptor antagonists, xenon has no neurotoxic side effects. Xenon also protects the heart in ischaemia-reperfusion situations. Xenon reduces the post-ischaemic reperfusion injury and offers cardioprotection by inducing pharmacological preconditioning. These organ protective properties of xenon might be useful in special clinical situations
U2 - https://doi.org/10.1055/s-2004-825736
DO - https://doi.org/10.1055/s-2004-825736
M3 - Article
C2 - 15319839
SN - 0939-2661
VL - 39
SP - 456
EP - 462
JO - Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie
JF - Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie
IS - 8
ER -