TY - CONF
T1 - Comparison of the back-to-back reproducibility of the Siena/FSL whole brain atrophy measurement at 3T and 1.5T using the ADNI MPRAGE MRIs
AU - Cover, Keith
AU - van Schijndel, Ronald
AU - Redolfi, Alberto
AU - Knol, Dirk
AU - Frisoni, Giovanni Battista
AU - Barkhof, Frederik
AU - Vrenken, Hugo
PY - 2011/8/2
Y1 - 2011/8/2
N2 - Background: There is substantial evidence to demonstrate that whole brain atrophy measurements perform significantly differently at 3T than1.5T [1]. MRI based measurement of atrophy, such as whole brain and hippocampus, are being used as biomarkers in diseases such as Alzheimer's disease (AD) and multiple sclerosis (MS). Thus a comparison of their respective performances at 3T and 1.5T for planning clinical trials is needed. The aim of this study is to compare the reproducibility of the Siena/FSL whole brain atrophy measurement algorithm at the two field strengths, using back-toback( BTB) MPRAGE MRI scans from the ADNI study acquired at both 3T and 1.5T for each subject. Methods: We selected ADNI subjects who had BTB
AB - Background: There is substantial evidence to demonstrate that whole brain atrophy measurements perform significantly differently at 3T than1.5T [1]. MRI based measurement of atrophy, such as whole brain and hippocampus, are being used as biomarkers in diseases such as Alzheimer's disease (AD) and multiple sclerosis (MS). Thus a comparison of their respective performances at 3T and 1.5T for planning clinical trials is needed. The aim of this study is to compare the reproducibility of the Siena/FSL whole brain atrophy measurement algorithm at the two field strengths, using back-toback( BTB) MPRAGE MRI scans from the ADNI study acquired at both 3T and 1.5T for each subject. Methods: We selected ADNI subjects who had BTB
UR - http://www.mendeley.com/research/comparison-backtoback-reproducibility-sienafsl-whole-brain-atrophy-measurement-3t-15t-using-adni-mpr
U2 - https://doi.org/10.1016/j.jalz.2011.05.158
DO - https://doi.org/10.1016/j.jalz.2011.05.158
M3 - Abstract
SP - S65-S66
ER -