Prognostic value of occult tumor cells obtained by peritoneal lavage in patients with resectable pancreatic cancer and no ascites: A systematic review

Willemijn Steen, Rachel Blom, Olivier Busch, Michael Gerhards, Marc Besselink, Frederike Dijk, Sebastiaan Festen

Research output: Contribution to journalReview articleAcademicpeer-review

14 Citations (Scopus)

Abstract

The poor survival of patients with resectable pancreatic cancer might be related to the presence of occult peritoneal tumor cells (OPTC). This systematic review studies the prognostic value of cytology and carcinoembryonic antigen (CEA) by real-time polymerase chain reaction in peritoneal fluid. The results suggest that presence of OPTC is related to a worse survival in patients with resectable pancreatic cancer. Future studies should investigate its possible role in selecting patients for specific treatment strategies. J. Surg. Oncol. 2016;114:743-751. © 2016 Wiley Periodicals, Inc
Original languageEnglish
Pages (from-to)743-751
JournalJournal of surgical oncology
Volume114
Issue number6
DOIs
Publication statusPublished - 2016

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