Hanneke Hulst

DR., Member of the Royal Young Academy, PhD, (Principal Investigator)


Research activity per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Research interests

My research interests are:

1) Deepening understanding of the underlying mechanisms of cognitive decline in MS (elaboration on the work started during my PhD) and;

2) (further) develop my own theme within the MS center Amsterdam: studying the effects of cognitive rehabilitation on behavior and quality of life on the one hand and brain structure and function (i.e. neuronal plasticity) on the other hand.

State-of-the-art neuroimaging measures are key in all projects I am involved in. One of my newest insights is the suggestion of a window-of-opportunity in which the brain seems most receptive for cognitive rehabilitation (i.e. intact functional network functioning). This window-of-opportunity is often missed in current clinical care and cognitive rehabilitation might, hence, often come too late. This finding also suggests that there might be a role for preventative intervention (i.e. making the brain more resilient towards future pathology), an area that I want to explore in the (near) future.

My ultimate goal is to understand the brain to such an extent that I will be able to give patient-tailored advices to prevent, or at least postpone, cognitive decline and to allow patients to live their life as they see fit without being hampered by MS-related cognitive decline. 

Key words: Cognition, state-of-the-art neuroimaging techiques, resilience, quality of life, patient narratives, personalised intervention

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or