Myron Best

Research output

Research output per year 2015 2020 2021 2023 2024

• 33 Article
• 5 Review article
• 1 Meeting Abstract
• 1 Phd-Thesis - Research and graduation external

Research output per year

Research output per year

Search results

• 2015

  Identification of a novel MET mutation in high-grade glioma resulting in an auto-active intracellular protein

  Navis, A. C., van Lith, S. A. M., van Duijnhoven, S. M. J., de Pooter, M., Yetkin-Arik, B., Wesseling, P., Hendriks, W. J. A. J., Venselaar, H., Timmer, M., van Cleef, P., van Bergen En Henegouwen, P., Best, M. G., Wurdinger, T. D., Tops, B. B. J. & Leenders, W. P. J., Jul 2015, In: Acta Neuropathologica. 130, 1, p. 131-44 14 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  34 Citations (Scopus)

• RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics

  Best, M. G., Sol, N., Kooi, E. I., Tannous, J., Westerman, A., Rustenburg, F., Schellen, P., Verschueren, H., Post, E., Koster, J., Ylstra, B., Ameziane, N., Dorsman, J., Smit, E. F., Verheul, H. M., Noske, D. P., Reijneveld, J. C., Nilsson, R. J. A., Tannous, B. A., Wesseling, P., & 1 othersWurdinger, T., 9 Nov 2015, In: Cancer cell. 28, 5, p. 666-676 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  621 Citations (Scopus)
• 2016

  Re: a Word of Caution on New and Revolutionary Diagnostic Tests

  Best, M. G., Sol, N., Tannous, B. A., Wesseling, P. & Wurdinger, T., 8 Feb 2016, In: Cancer cell. 29, 2, p. 143-4 2 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  2 Citations (Scopus)
• 2017

  Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets

  Best, M. G., Sol, N., In 't Veld, S. G. J. G., Vancura, A., Muller, M., Niemeijer, A-L. N., Fejes, A. V., Tjon Kon Fat, L-A., Huis In 't Veld, A. E., Leurs, C., Le Large, T. Y., Meijer, L. L., Kooi, I. E., Rustenburg, F., Schellen, P., Verschueren, H., Post, E., Wedekind, L. E., Bracht, J., Esenkbrink, M., & 34 othersWils, L., Favaro, F., Schoonhoven, J. D., Tannous, J., Meijers-Heijboer, H., Kazemier, G., Giovannetti, E., Reijneveld, J. C., Idema, S., Killestein, J., Heger, M., de Jager, S. C., Urbanus, R. T., Hoefer, I. E., Pasterkamp, G., Mannhalter, C., Gomez-Arroyo, J., Bogaard, H-J., Noske, D. P., Vandertop, W. P., van den Broek, D., Ylstra, B., Nilsson, R. J. A., Wesseling, P., Karachaliou, N., Rosell, R., Lee-Lewandrowski, E., Lewandrowski, K. B., Tannous, B. A., de Langen, A. J., Smit, E. F., van den Heuvel, M. M., Wurdinger, T. & In ‘t Veld, S. G. J. G., 14 Aug 2017, In: Cancer cell. 32, 2, p. 238-252.e9

  Research output: Contribution to journal › Article › Academic › peer-review
  215 Citations (Scopus)
• 2018

  Impact of Escherichia coli K12 and O18:K1 on human platelets: Differential effects on platelet activation, RNAs and proteins

  Fejes, A. V., Best, M. G., van der Heijden, W. A., Vancura, A., Verschueren, H., de Mast, Q., Wurdinger, T. & Mannhalter, C., 1 Nov 2018, In: Scientific reports. 8, 1, p. 16145 16145.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  10 Citations (Scopus)
• 2019

  RNA sequencing and swarm intelligence–enhanced classification algorithm development for blood-based disease diagnostics using spliced blood platelet RNA

  Best, M. G., in ’t Veld, S. G. J. G., Sol, N., Wurdinger, T. & In 't Veld, S. G. J. G., 1 Apr 2019, In: Nature protocols. 14, 4, p. 1206-1234 29 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  76 Citations (Scopus)
• 2020

  Blood platelet RNA enables the detection of multiple sclerosis

  Sol, N., Leurs, C. E., Veld, S. G. I. ., Strijbis, E. M., Vancura, A., Schweiger, M. W., Teunissen, C. E., Mateen, F. J., Tannous, B. A., Best, M. G., Würdinger, T., Killestein, J. & Veld, S. GJG. I. ., 28 Aug 2020, In: Multiple sclerosis journal - experimental, translational and clinical. 6, 3, p. 2055217320946784

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  13 Citations (Scopus)

• Glioblastomas exploit truncated O-linked glycans for local and distant immune modulation via the macrophage galactose-type lectin

  Dusoswa, S. A., Verhoeff, J., Abels, E., Méndez-Huergo, S. P., Croci, D. O., Kuijper, L. H., de Miguel, E., Wouters, V. M. C. J., Best, M. G., Rodriguez, E., Cornelissen, L. A. M., van Vliet, S. J., Wesseling, P., Breakefield, X. O., Noske, D. P., Würdinger, T., Broekman, M. L. D., Rabinovich, G. A., van Kooyk, Y. & Garcia-Vallejo, J. J., 18 Feb 2020, In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 117, 7, p. 3693-3703 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  55 Citations (Scopus)

• RNA-Sequencing of Tumor-Educated Platelets, a Novel Biomarker for Blood-Based Sarcoma Diagnostics

  Heinhuis, K. M., In 't Veld, S. G. J. G., Dwarshuis, G., van den Broek, D., Sol, N., Best, M. G., Coevorden, F. V., Haas, R. L., Beijnen, J. H., van Houdt, W. J., Würdinger, T. & Steeghs, N., Jun 2020, In: Cancers. 12, 6, 1372.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  33 Citations (Scopus)

• The bivariate NRIP1/ZEB2 RNA marker permits non-invasive presymptomatic screening of pre-eclampsia

  Manders, V., Visser, A., Keijser, R., Min, N., Poutsma, A., Mulders, J., van den Berkmortel, T., Hortensius, M., Jongejan, A., Pajkrt, E., Sistermans, E. A., Sie, D., Best, M. G., Würdinger, T., de Boer, M., Afink, G. & Oudejans, C., 14 Dec 2020, In: Scientific reports. 10, 1, p. 21857 1 p., 21857.

  Research output: Contribution to journal › Article › Academic › peer-review
  4 Citations (Scopus)

• Tumor-Educated Platelet RNA for the Detection and (Pseudo)progression Monitoring of Glioblastoma

  Sol, N., in ‘t Veld, S. G. J. G., Vancura, A., Tjerkstra, M., Leurs, C., Rustenburg, F., Schellen, P., Verschueren, H., Post, E., Zwaan, K., Ramaker, J., Wedekind, L. E., Tannous, J., Ylstra, B., Killestein, J., Mateen, F., Idema, S., de Witt Hamer, P. C., Navis, A. C., Leenders, W. P. J., & 10 othersHoeben, A., Moraal, B., Noske, D. P., Vandertop, W. P., Nilsson, R. J. A., Tannous, B. A., Wesseling, P., Reijneveld, J. C., Best, M. G. & Wurdinger, T., 20 Oct 2020, In: Cell Reports Medicine. 1, 7, p. 100101 100101.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  56 Citations (Scopus)

• Tumor-educated platelets for the earlier detection of hepatocellular carcinoma

  Best, M. G. & Wurdinger, T., Nov 2020, In: Clinics and research in hepatology and gastroenterology. 44, 6, p. 794-795 2 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  6 Citations (Scopus)
• 2021

  Circular RNA Sequencing of Maternal Platelets: A Novel Tool for the Identification of Pregnancy-Specific Biomarkers

  Oudejans, C., Manders, V., Visser, A., Keijser, R., Min, N., Poutsma, A., Mulders, J., van den Berkmortel, T., Wigman, D-J., Blanken, B., Jongejan, A., Pajkrt, E., de Boer, M., Sistermans, E. A., Sie, D., Best, M. G., Würdinger, T. & Afink, G., 1 Mar 2021, In: Clinical chemistry. 67, 3, p. 508-517 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  6 Citations (Scopus)

• Diagnostic accuracy of liquid biopsy in endometrial cancer

  Łukasiewicz, M., Pastuszak, K., Łapińska-Szumczyk, S., Różański, R., in ‘t Veld, S. G. J. G., Bieńkowski, M., Stokowy, T., Ratajska, M., Best, M. G., Würdinger, T., Żaczek, A. J., Supernat, A. & Jassem, J., 1 Nov 2021, In: Cancers. 13, 22, 5731.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  11 Citations (Scopus)

• imPlatelet classifier: image-converted RNA biomarker profiles enable blood-based cancer diagnostics

  Pastuszak, K., Supernat, A., Best, M. G., in 't Veld, S. G. J. G., Łapińska-Szumczyk, S., Łojkowska, A., Różański, R., Żaczek, A. J., Jassem, J., Würdinger, T. & Stokowy, T., Oct 2021, In: Molecular Oncology. 15, 10, p. 2688-2701 14 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  12 Citations (Scopus)

• Novel biomarkers to detect occult cancer in patients with unprovoked venous thromboembolism: Rationale and design of the PLATO-VTE study

  Kraaijpoel, N., Mulder, F. I., Carrier, M., van Lieshout, A., Würdinger, T., Best, M. G., van Vlijmen, B. J. M., Mohammed, Y., Jara-Palomares, L., Kamphuisen, P. W., di Nisio, M., Ageno, W., Beyer-Westendorf, J., Vanassche, T., Klokm, F. A., Otten, H-M., Peters, M. J. L., Cosmi, B., Wolde, M. T., Bossuyt, P. M. M., & 2 othersBüller, H. R. & van Es, N., 1 Jan 2021, In: Thrombosis Update. 2, 100030.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  3 Citations (Scopus)

• The Analysis of Platelet-Derived circRNA Repertoire as Potential Diagnostic Biomarker for Non-Small Cell Lung Cancer

  D’ambrosi, S., Visser, A., Antunes-Ferreira, M., Poutsma, A., Giannoukakos, S., Sol, N., Sabrkhany, S., Bahce, I., Kuijpers, M. J. E., Oude Egbrink, M. G. A., Griffioen, A. W., Best, M. G., Koppers-Lalic, D., Oudejans, C., Würdinger, T. & D'Ambrosi, S., 16 Sept 2021, In: Cancers. 13, 18, 4644.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  25 Citations (Scopus)

• The brain-derived neurotrophic factor prompts platelet aggregation and secretion

  Boukhatem, I., Fleury, S., Welman, M., Le Blanc, J., Thys, C., Freson, K., Best, M. G., Würdinger, T., Allen, B. G. & Lordkipanidzé, M., 28 Sept 2021, In: Blood advances. 5, 18, p. 3568-3580 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  14 Citations (Scopus)

• Transcriptomic landscape of blood platelets in healthy donors

  Supernat, A., Popęda, M., Pastuszak, K., Best, M. G., Grešner, P., Veld, S. I. ., Siek, B., Bednarz-Knoll, N., Rondina, M. T., Stokowy, T., Wurdinger, T., Jassem, J., Żaczek, A. J. & Veld, S. I. ., 1 Dec 2021, In: Scientific reports. 11, 1, p. 15679 15679.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  23 Citations (Scopus)

• Uncommon presentations of a neurosurgical site infection: impaired wound healing with hypergranulation and crust formation

  Buis, D. R., Arnts, H., Slot, K. M., Best, M. G. & Vandertop, W. P., 2021, (E-pub ahead of print) In: Acta neurochirurgica.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2022

  Blood platelets as an RNA biomarker platform for neuro-oncological diseases

  Post, E., Sol, N., Best, M. G. & Wurdinger, T., 1 Nov 2022, In: Neuro-oncology advances. 4, Suppl 2, p. II61-II65

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Detection and localization of early- and late-stage cancers using platelet RNA

  In 't Veld, S. G. J. G., Arkani, M., Post, E., Antunes-Ferreira, M., D'Ambrosi, S., Vessies, D. C. L., Vermunt, L., Vancura, A., Muller, M., Niemeijer, A-L. N., Tannous, J., Meijer, L. L., Le Large, T. Y. S., Mantini, G., Wondergem, N. E., Heinhuis, K. M., van Wilpe, S., Smits, A. J., Drees, E. E. E., Roos, E., & 96 othersLeurs, C. E., Tjon Kon Fat, L-A., van der Lelij, E. J., Dwarshuis, G., Kamphuis, M. J., Visser, L. E., Harting, R., Gregory, A., Schweiger, M. W., Wedekind, L. E., Ramaker, J., Zwaan, K., Verschueren, H., Bahce, I., de Langen, A. J., Smit, E. F., van den Heuvel, M. M., Hartemink, K. J., Kuijpers, M. J. E., Oude Egbrink, M. G. A., Griffioen, A. W., Rossel, R., Hiltermann, T. J. N., Lee-Lewandrowski, E., Lewandrowski, K. B., De Witt Hamer, P. C., Kouwenhoven, M., Reijneveld, J. C., Leenders, W. P. J., Hoeben, A., Verdonck-de Leeuw, I. M., Leemans, C. R., Baatenburg de Jong, R. J., Terhaard, C. H. J., Takes, R. P., Langendijk, J. A., de Jager, S. C., Kraaijeveld, A. O., Pasterkamp, G., Smits, M., Schalken, J. A., Łapińska-Szumczyk, S., Łojkowska, A., Żaczek, A. J., Lokhorst, H., van de Donk, N. W. C. J., Nijhof, I., Prins, H-J., Zijlstra, J. M., Idema, S., Baayen, J. C., Teunissen, C. E., Killestein, J., Besselink, M. G., Brammen, L., Bachleitner-Hofmann, T., Mateen, F., Plukker, J. T. M., Heger, M., de Mast, Q., Lisman, T., Pegtel, D. M., Bogaard, H-J., Jassem, J., Supernat, A., Mehra, N., Gerritsen, W., de Kroon, C. D., Lok, C. A. R., Piek, J. M. J., Steeghs, N., van Houdt, W. J., Brakenhoff, R. H., Sonke, G. S., Verheul, H. M., Giovannetti, E., Kazemier, G., Sabrkhany, S., Schuuring, E., Sistermans, E. A., Wolthuis, R., Meijers-Heijboer, H., Dorsman, J., Oudejans, C., Ylstra, B., Westerman, B. A., van den Broek, D., Koppers-Lalic, D., Wesseling, P., Nilsson, R. J. A., Vandertop, W. P., Noske, D. P., Tannous, B. A., Sol, N., Best, M. G. & Wurdinger, T., 12 Sept 2022, In: Cancer cell. 40, 9, p. 999-1009.e6 18 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  32 Citations (Scopus)

• Distinct Platelet Ribonucleic Acid Signatures in Patients with Pulmonary Hypertension

  Smits, A. J., Arkani, M., In 't Veld, S. G. J. G., Huis In 't Veld, A. E., Sol, N., Groeneveldt, J. A., Botros, L., Braams, N. J., Jansen, S. M., Ramaker, J., Zwaan, K., Post, E., Nossent, E. J., Boonstra, A., de Man, F. S., Vonk Noordegraaf, A., Gomez-Arroyo, J., Best, M. G., Wurdinger, T. & Bogaard, H. J., 1 Oct 2022, In: Annals of the American Thoracic Society. 19, 10, p. 1650-1660 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  3 Citations (Scopus)

• Whole transcriptome profiling of liquid biopsies from tumour xenografted mouse models enables specific monitoring of tumour-derived extracellular RNA

  Vermeirssen, V., Deleu, J., Morlion, A., Everaert, C., De Wilde, J., Anckaert, J., Durinck, K., Nuytens, J., Rishfi, M., Speleman, F., Van Droogenbroeck, H., Verniers, K., Baietti, M. F., Albersen, M., Leucci, E., Post, E., Best, M. G., Van Maerken, T., De Wilde, B., Vandesompele, J., & 1 othersDecock, A., 1 Dec 2022, In: NAR Cancer. 4, 4, p. zcac037 zcac037.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  4 Citations (Scopus)
• 2023

  Blood platelet RNA profiles do not enable for nivolumab response prediction at baseline in patients with non-small cell lung cancer

  Muller, M., Best, M. G., van der Noort, V., Hiltermann, T. J. N., Niemeijer, A-L. N., Post, E., Sol, N., In 't Veld, S. G. J. G., Nogarede, T., Visser, L., Schouten, R. D., van den Broek, D., Hummelink, K., Monkhorst, K., de Langen, A. J., Schuuring, E., Smit, E. F., Groen, H. J. M., Wurdinger, T. & van den Heuvel, M. M., 26 May 2023, (E-pub ahead of print) In: Tumour biology.

  Research output: Contribution to journal › Article › Academic › peer-review

• Discrimination Between Pre-and Postcapillary Pulmonary Hypertension Using Platelet RNA

  Arkani, M., Kianzad, A., Jansen, S., Smit, J., Post, E., Ramaker, J., Lagerweij, T., in’t Veld, S. G. J. G., Noske, D. P., Noordegraaf, A. V., Wurdinger, T., Best, M. G. & Bogaard, H-J., 4 Jul 2023, In: Journal of the American Heart Association. 12, 13, p. e028447 e028447.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• In vitro cross-talk between metastasis-competent circulating tumor cells and platelets in colon cancer: a malicious association during the harsh journey in the blood

  Eslami-S, Z., Cortés-Hernández, L. E., Glogovitis, I., Antunes-Ferreira, M., D’Ambrosi, S., Kurma, K., Garima, F., Cayrefourcq, L., Best, M. G., Koppers-Lalic, D., Wurdinger, T. & Alix-Panabières, C., 2023, In: Frontiers in cell and developmental biology. 11, p. 1209846 1209846.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  1 Citation (Scopus)

• Platelet-Based Liquid Biopsies through the Lens of Machine Learning

  Cygert, S., Pastuszak, K., Górski, F., Sieczczyński, M., Juszczyk, P., Rutkowski, A., Lewalski, S., Różański, R., Jopek, M. A., Jassem, J., Czyżewski, A., Wurdinger, T., Best, M. G., Żaczek, A. J. & Supernat, A., 1 Apr 2023, In: Cancers. 15, 8, 2336.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  2 Citations (Scopus)

• Platelet RNA enables accurate detection of ovarian cancer: an intercontinental, biomarker identification study

  Gao, Y., Liu, C-J., Li, H-Y., Xiong, X-M., Li, G-L., in 't Veld, S. G. J. G., Cai, G-Y., Xie, G-Y., Zeng, S-Q., Wu, Y., Chi, J-H., Liu, J-H., Zhang, Q., Jiao, X-F., Shi, L-L., Lu, W-R., Lv, W-G., Yang, X-S., Piek, J. M. J., de Kroon, C. D., & 16 othersLok, C. A. R., Supernat, A., Łapińska-Szumczyk, S., Łojkowska, A., Żaczek, A. J., Jassem, J., Tannous, B. A., Sol, N., Post, E., Best, M. G., Kong, B-H., Xie, X., Ma, D., Wurdinger, T., Guo, A-Y. & Gao, Q-L., 7 Jun 2023, In: Protein and Cell. 14, 6, p. 433-447 15 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  3 Citations (Scopus)

• Platelet RNA sequencing for cancer screening in patients with unprovoked venous thromboembolism: a prospective cohort study

  Mulder, F. I., Kraaijpoel, N., Carrier, M., Guman, N. A., Jara-Palomares, L., Di Nisio, M., Ageno, W., Beyer-Westendorf, J., Klok, F. A., Vanassche, T., Otten, H-M. B., Cosmi, B., Wolde, M. T., In 't Veld, S. G. J. G., Post, E., Ramaker, J., Zwaan, K., Peters, M., Delluc, A., Kamphuisen, P. W., & 7 othersSanchez-Lopez, V., Porreca, E., Bossuyt, P. M. M., Büller, H. R., Wurdinger, T., Best, M. G. & van Es, N., 1 Apr 2023, In: Journal of thrombosis and haemostasis : JTH. 21, 4, p. 905-916 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Tumor-educated platelet blood tests for Non-Small Cell Lung Cancer detection and management

  Antunes-Ferreira, M., D’Ambrosi, S., Arkani, M., Post, E., in ‘t Veld, S. G. J. G., Ramaker, J., Zwaan, K., Kucukguzel, E. D., Wedekind, L. E., Griffioen, A. W., Oude Egbrink, M., Kuijpers, M. J. E., van den Broek, D., Noske, D. P., Hartemink, K. J., Sabrkhany, S., Bahce, I., Sol, N., Bogaard, H-J., Koppers-Lalic, D., & 2 othersBest, M. G. & Wurdinger, T., 1 Dec 2023, In: Scientific reports. 13, 1, p. 9359 9359.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  3 Citations (Scopus)
• 2024

  Blood platelet RNA profiles do not enable for nivolumab response prediction at baseline in patients with non-small cell lung cancer

  Muller, M., Best, M. G., van der Noort, V., Hiltermann, T. J. N., Niemeijer, A-L. N., Post, E., Sol, N., in 't Veld, S. G. J. G., Nogarede, T., Visser, L., Schouten, R. D., van den Broek, D., Hummelink, K., Monkhorst, K., de Langen, A. J., Schuuring, E., Smit, E. F., Groen, H. J. M., Wurdinger, T. & van den Heuvel, M. M., 19 Mar 2024, In: Tumor Biology. 46, s1, p. S327-S340

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  2 Citations (Scopus)

• Deep Learning-Based, Multiclass Approach to Cancer Classification on Liquid Biopsy Data

  Jopek, M. A., Pastuszak, K., Cygert, S., Best, M. G., Wurdinger, T., Jassem, J., Zaczek, A. J. & Supernat, A., 2024, In: IEEE Journal of Translational Engineering in Health and Medicine. 12, p. 306-313 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access