Projects per year
Personal profile
specialisation
Scientific director Alzheimer center Amsterdam
Pasman chair: Determinants of cognitive decline and dementia.
Background in neuropsychology and clinical epidemiology.
Research interests
Research of Alzheimer center Amsterdam works towards personalized medicine for Alzheimer's disease and other causes of dementia, with a focus on early onset dementia. Our research lines (1) finding the origin, (2) diagnosis & prognosis, (3) intervention & prevention.
Education/Academic qualification
Basis Kwalificatie Onderwijs (BKO), VUmc
Award Date: 26 Nov 2012
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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AD-RIDDLE: Real-word implementatin, deployment and validation of early detection tools and lifestyle enhancement.
1/01/2024 → 31/12/2028
Project: Research
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Multi-Memo: Shorter- and longer-term mechanisms of multimodal interventions to prevent dementia
1/05/2023 → 30/04/2026
Project: Research
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PROMINENT: Precision medicine platform in neurodegenerative disease
1/05/2023 → 30/04/2028
Project: Research
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TAP-Dementia: Timely, accurate and personalized diagnosis of dementia
1/01/2023 → 31/12/2026
Project: Research
Research output
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Adaptive immune changes associate with clinical progression of Alzheimer's disease
van Olst, L., Kamermans, A., Halters, S., van der Pol, S. M. A., Rodriguez, E., Verberk, I. M. W., Verberk, S. G. S., Wessels, D. W. R., Rodriguez-Mogeda, C., Verhoeff, J., Wouters, D., Van den Bossche, J., Garcia-Vallejo, J. J., Lemstra, A. W., Witte, M. E., van der Flier, W. M., Teunissen, C. E. & de Vries, H. E., 1 Dec 2024, In: Molecular Neurodegeneration. 19, 1, p. 38 38.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Alzheimer's Disease and Cognitive Decline in Patients with Cardiovascular Diseases Along the Heart-Brain Axis
Heart-Brain Connection Consortium, 2 Apr 2024, In: Journal of Alzheimer's disease : JAD. 98, 3, p. 987-1000 14 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Amyloid pathology and vascular risk are associated with distinct patterns of cerebral white matter hyperintensities: A multicenter study in 3132 memory clinic patients
Biesbroek, J. M., Coenen, M., DeCarli, C., Fletcher, E. M., Maillard, P. M., Barkhof, F., Barnes, J., Benke, T., Chen, C. P. L. H., Dal-Bianco, P., Dewenter, A., Duering, M., Enzinger, C., Ewers, M., Exalto, L. G., Franzmeier, N., Hilal, S., Hofer, E., Koek, H. L., Maier, A. B., & 20 others, 1 Apr 2024, In: Alzheimer's and Dementia. 20, 4, p. 2980-2989 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Association of amyloid-beta with depression or depressive symptoms in older adults without dementia: a systematic review and meta-analysis
Twait, E. L., Wu, J-H., Kamarioti, M., Basten, M., van der Flier, W. M., Gerritsen, L. & Geerlings, M. I., Dec 2024, In: Translational Psychiatry. 14, 1, p. 25 25.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access -
Blood Pressure Variability and Plasma Biomarkers of Neuronal Injury and Alzheimer's Disease: A Clinic-Based Study of Patients with Diseases Along the Heart-Brain Axis
Heart-Brain Connection Consortium, 21 May 2024, (E-pub ahead of print) In: Journal of Alzheimer's disease : JAD.Research output: Contribution to journal › Article › Academic › peer-review
Datasets
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Additional file 2 of Four subgroups based on tau levels in Alzheimer’s disease observed in two independent cohorts
Duits, F. (Creator), Wesenhagen, K. E. J. (Creator), Ekblad, L. (Creator), Wolters, E. (Creator), Willemse, E. (Creator), Scheltens, P. (Creator), van der Flier, W. (Creator), Teunissen, C. (Creator), Visser, P. (Creator), Tijms, B. (Creator), Scheltens, P. (Creator), Flier, W. M. V. D. (Contributor), Teunissen, C. E. (Creator), Visser, P. J. (Creator) & Tijms, B. M. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.13521232, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Four_subgroups_based_on_tau_levels_in_Alzheimer_s_disease_observed_in_two_independent_cohorts/13521232
Dataset
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Additional file 2 of Four subgroups based on tau levels in Alzheimer’s disease observed in two independent cohorts
Duits, F. (Creator), Wesenhagen, K. E. J. (Creator), Ekblad, L. (Creator), Wolters, E. (Creator), Willemse, E. (Creator), Scheltens, P. (Creator), van der Flier, W. (Creator), Teunissen, C. (Creator), Visser, P. (Creator), Tijms, B. (Creator), Scheltens, P. (Creator), Flier, W. M. V. D. (Contributor), Teunissen, C. E. (Creator), Visser, P. J. (Creator) & Tijms, B. M. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.13521232.v1, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Four_subgroups_based_on_tau_levels_in_Alzheimer_s_disease_observed_in_two_independent_cohorts/13521232/1
Dataset
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Data from: Cognitive reserve and clinical progression in Alzheimer’s disease: a paradoxical relationship
van Loenhoud, A. (Creator), van der Flier, W. (Creator), Wink, A. M. (Creator), Dicks, E. (Creator), Groot, C. (Creator), Twisk, J. (Creator), Barkhof, F. (Creator), Scheltens, P. (Creator), Ossenkoppele, R. (Creator) & Scheltens, P. (Creator), Dryad, 23 Nov 2019
DOI: 10.5061/dryad.cb0qk1g, https://datadryad.org/stash/dataset/doi:10.5061/dryad.cb0qk1g
Dataset
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Data from: Cognitive reserve and clinical progression in Alzheimer's disease: a paradoxical relationship
van Loenhoud, A. (Contributor), van der Flier, W. (Contributor), Wink, A. M. (Contributor), Dicks, E. (Contributor), Groot, C. (Contributor), Twisk, J. (Contributor), Barkhof, F. (Contributor), Scheltens, P. (Contributor), Ossenkoppele, R. (Contributor) & Scheltens, P. (Contributor), Zenodo, 23 Nov 2019
DOI: 10.5061/dryad.cb0qk1g, https://zenodo.org/record/4955054
Dataset
Activities
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Unmet needs in Neurodegenerative Diseases.
Wiesje van der Flier (Consultant)
31 Mar 2023Activity: Consultancy › Academic
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Evidence generation steering committee Biomarkers
Wiesje van der Flier (Consultant)
29 Mar 2023 → 31 Dec 2024Activity: Consultancy › Academic
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Alzheime's disease round table
Wiesje van der Flier (Consultant)
14 Jul 2023Activity: Consultancy › Academic
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Clinical Advances in Alzheimer’s Disease: Preparing for the Future
Wiesje van der Flier (Consultant)
1 Jan 2023 → 31 Dec 2023Activity: Consultancy › Academic
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Evoke/Evoke+ steering committee
Wiesje van der Flier (Consultant)
1 Oct 2023 → …Activity: Consultancy › Academic
Press/Media
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Podcast: Hear from her
Wiesje van der Flier & Antonella Santuccione Chadha
22/11/2023
1 Media contribution
Press/Media: Public Engagement Activities
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Geen genezing, toch opluchting: het is alzheimer
14/09/2023
1 Media contribution
Press/Media: Press / Media
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Groot Alzheimercongres belicht hoopvolle ontwikkelingen
22/07/2023
1 Media contribution
Press/Media: Press / Media
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