Gerard Hovingh

2015

A systematic review and meta-analysis of the effect of statins on plasma asymmetric dimethylarginine concentrations

Serban, C., Sahebkar, A., Ursoniu, S., Mikhailidis, D. P., Rizzo, M., Lip, G. Y. H., Kees Hovingh, G., Kastelein, J. J. P., Kalinowski, L., Rysz, J. & Banach, M., 2015, In: Scientific reports. 5, p. 9902

Research output: Contribution to journal › Article › Academic › peer-review

143 Citations (Scopus)

Biological interpretation of genome-wide association studies using predicted gene functions

AUTHOR GROUP, 2015, In: Nature communications. 6, p. 5890

Research output: Contribution to journal › Article › Academic › peer-review

513 Citations (Scopus)

Cholesterol ester transfer protein inhibition by TA-8995 in patients with mild dyslipidaemia (TULIP): a randomised, double-blind, placebo-controlled phase 2 trial

Hovingh, G. K., Kastelein, J. J. P., van Deventer, S. J. H., Round, P., Ford, J., Saleheen, D., Rader, D. J., Brewer, H. B. & Barter, P. J., 2015, In: Lancet. 386, 9992, p. 452-460

Research output: Contribution to journal › Article › Academic › peer-review

165 Citations (Scopus)

Clinical Features of Lysosomal Acid Lipase Deficiency

Burton, B. K., Deegan, P. B., Enns, G. M., Guardamagna, O., Horslen, S., Hovingh, G. K., Lobritto, S. J., Malinova, V., McLin, V. A., Raiman, J., Di Rocco, M., Santra, S., Sharma, R., Sykut-Cegielska, J., Whitley, C. B., Eckert, S., Valayannopoulos, V. & Quinn, A. G., 2015, In: Journal of pediatric gastroenterology and nutrition. 61, 6, p. 619-625

Research output: Contribution to journal › Article › Academic › peer-review

91 Citations (Scopus)

Dyslipidaemia: Lysosomal acid lipase deficiency-a cautious leap forward

Hollak, C. E. M. & Hovingh, G. K., 2015, In: Nature reviews. Endocrinology. 11, 12, p. 696-697

Research output: Contribution to journal › Editorial › Academic › peer-review

2 Citations (Scopus)

Effect of open-label infusion of an apoA-I-containing particle (CER-001) on RCT and artery wall thickness in patients with FHA

Kootte, R. S., Smits, L. P., van der Valk, F. M., Dasseux, J-L., Keyserling, C. H., Barbaras, R., Paolini, J. F., Santos, R. D., van Dijk, T. H., Dallinga-van Thie, G. M., Nederveen, A. J., Mulder, W. J. M., Hovingh, G. K., Kastelein, J. J. P., Groen, A. K. & Stroes, E. S., 2015, In: Journal of Lipid Research. 56, 3, p. 703-712

Research output: Contribution to journal › Article › Academic › peer-review

71 Citations (Scopus)

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

AUTHOR GROUP, 2015, In: NATURE. 518, 7537, p. 102-+

Research output: Contribution to journal › Article › Academic › peer-review

534 Citations (Scopus)

Exome sequencing in suspected monogenic dyslipidemias

Stitziel, N. O., Peloso, G. M., Abifadel, M., Cefalu, A. B., Fouchier, S., Motazacker, M. M., Tada, H., Larach, D. B., Awan, Z., Haller, J. F., Pullinger, C. R., Varret, M., Rabès, J-P., Noto, D., Tarugi, P., Kawashiri, M-A., Nohara, A., Yamagishi, M., Risman, M., deo, R., & 20 othersRuel, I., Shendure, J., Nickerson, D. A., Wilson, J. G., Rich, S. S., Gupta, N., Farlow, D. N., Neale, B. M., Daly, M. J., Kane, J. P., Freeman, M. W., Genest, J., Rader, D. J., Mabuchi, H., Kastelein, J. J. P., Hovingh, G. K., Averna, M. R., Gabriel, S., Boileau, C. & Kathiresan, S., 2015, In: Circulation. Cardiovascular genetics. 8, 2, p. 343-350

Research output: Contribution to journal › Article › Academic › peer-review

42 Citations (Scopus)

Familial hypercholesterolaemia: A global call to arms

Vallejo-Vaz, A. J., Kondapally Seshasai, S. R., Cole, D., Hovingh, G. K., Kastelein, J. J. P., Mata, P., Raal, F. J., Santos, R. D., Soran, H., Watts, G. F., Abifadel, M., Aguilar-Salinas, C. A., Akram, A., Alnouri, F., Alonso, R., Al-Rasadi, K., Banach, M., Bogsrud, M. P., Bourbon, M., Bruckert, E., & 27 othersCar, J., Corral, P., Descamps, O., Dieplinger, H., Durst, R., Freiberger, T., Gaspar, I. M., Genest, J., Harada-Shiba, M., Jiang, L., Kayikcioglu, M., Lam, C. S. P., Latkovskis, G., Laufs, U., Liberopoulos, E., Nilsson, L., Nordestgaard, B. G., O'Donoghue, J. M., Sahebkar, A., Schunkert, H., Shehab, A., Stoll, M., Su, T-C., Susekov, A., Widén, E., Catapano, A. L. & Ray, K. K., 2015, In: Atherosclerosis. 243, 1, p. 257-259

Research output: Contribution to journal › Article › Academic › peer-review

148 Citations (Scopus)

Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment

AUTHOR GROUP, 2015, In: European Heart journal. 36, 36, p. 2425-2437

Research output: Contribution to journal › Review article › Academic › peer-review

616 Citations (Scopus)

Genetically Determined Height and Coronary Artery Disease

AUTHOR GROUP, 2015, In: New England journal of medicine. 372, 17, p. 1608-1618

Research output: Contribution to journal › Article › Academic › peer-review

186 Citations (Scopus)

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

AUTHOR GROUP, 2015, In: Nature Genetics. 47, 12, p. 1415-+

Research output: Contribution to journal › Article › Academic › peer-review

302 Citations (Scopus)

Genetic studies of body mass index yield new insights for obesity biology

AUTHOR GROUP, Maegi, R., Kanoni, S., Kleber, M. E., Kristiansson, K., Lim, U., Lotay, V., Mangino, M., Leach, I. M., Medina-Gomez, C., Medland, S. E., Nalls, M. A., Palmer, C. D., Pasko, D., Pechlivanis, S., Peters, MJ., Prokopenko, I., Shungin, D., Stancakova, A., Strawbridge, R. J., & 414 othersSung, Y. J., Teumer, A., Trompet, S., van der Laan, S. W., van Settee, J., Van Vliet-Ostaptchouk, J. V., Wang, Z., Yengo, L., Zhang, W., Isaacs, A., Albrecht, E., Arnlov, J., Arscott, G. M., Attwood, A. P., Bandinelli, S., Barrett, A., Bas, I. N., Bellis, C., Bennett, A. J., Berne, C., Blagieva, R., Blueher, M., Bohringer, S., Bonnycastle, L. L., Boettcher, Y., Boyd, H. A., Bruinenberg, M., Caspersen, I. H., Chen, Y. I., Clarke, R., Daw, E. W., de Craen, A. J. M., Delgado, G., Dimitriou, M., Doney, A. S. F., Eklund, N., Estrada, K., Eury, E., Folkersen, L., Fraser, R. M., Garcia, M. E., Geller, F., Giedraitis, V., Gigante, B., Go, A. S., Golay, A., Goodall, A. H., Gordon, S. D., Gorski, M., Grabe, H., Grallert, H., Grammer, T. B., Graessler, J., Gronberg, H., Groves, C. J., Gusto, G., Haessler, J., Hall, P., Haller, T., Hallmans, G., Hartman, C. A., Hassinen, M., Hayward, C., Heard-Costa, N. L., Helmer, Q., Hengstenberg, C., Holmen, O., Hottenga, J. J., James, A. L., Jeff, J. M., Johansson, A., Jolley, J., Juliusdottir, T., Kinnunen, L., Koenig, W., Koskenvuo, M., Kratzer, W., Laitinen, J., Lamina, C., Leander, K., Lee, N. R., Lichtner, P., Lind, L., Lindstrom, J., Lo, K. S., Lobbens, S., Lorbeer, R., Lu, Y., Mach, F., Magnusson, P. K. E., Mahajan, A., McArdle, W. L., McLachlan, S., Menni, C., Merger, S., Mihailov, E., Milani, L., Moayyeri, A., Monda, K. L., Morken, M. A., Mulas, A., Mueller, G., Mueller-Nurasyid, M., Musk, A. W., Nagaraja, R., Noethen, M. M., Nolte, I. M., Pilz, S., Rayner, N. W., Renstrom, F., Rettig, R., Ried, J. S., Ripke, S., Robertson, N. R., Rose, L. M., Sanna, S., Scharnagl, H., Scholtens, S., Schumacher, F. R., Scott, W. R., Seufferlein, T., Shi, J., Smith, A. V., Smolonska, J., Stanton, A. V., Steinthorsdottir, V., Stirrups, K., Stringham, H. M., Sundstrom, J., Swertz, M. A., Swift, A. J., Syvanen, A., Tan, S., Tayo, B. O., Thorand, B., Thorleifsson, G., Tyrer, J. P., Uh, H., Vandenput, L., Verhulst, F. C., Vermeulen, S. H., Verweij, N., Vonk, J. M., Waite, L. L., Warren, H. R., Waterworth, D., Weedon, M. N., Wilkens, L. R., Willenborg, C., Wilsgaard, T., Wojczynski, M. K., Wong, A., Wrightl, A. F., Zhang, Q., Brennan, E. P., Choi, M., Dastani, Z., Drong, A. W., Eriksson, P., Franco-Cereceda, A., Gadin, J. R., Gharavi, A. G., Goddard, M. E., Handsaker, R. E., Huang, J., Karpe, F., Kathiresan, S., Keildson, S., Kiryluk, K., Kubo, M., Lee, J., Liang, L., Lifton, R. P., Ma, B., McCarroll, S. A., McKnight, A. J., Min, J. L., Moffatt, M. F., Montgomery, G. W., Murabito, J. M., Nicholson, G., Nyholt, DR., Okada, Y., Perry, J. R. B., Dorajoo, R., Reinmaa, E., Salem, R. M., Sandholm, N., Scott, R. A., Stolk, L., Takahashi, A., Tanaka, T., van 't Hooft, F. M., Vinkhuyzen, A. A. E., Westra, H., Zheng, W., Zondervan, K. T., Heath, A. C., Arveiler, D., Bakker, S. J. L., Beilby, J., Bergman, R. N., Blangero, J., Bovet, P., Campbell, H., Caulfield, M. J., Cesana, G., Chakravarti, A., Chasman, D. I., Chines, P. S., Collins, F. S., Crawford, D. C., Cupples, L. A., Cusi, D., Danesh, J., de Faire, U., den Ruijter, H. M., Dominiczak, A. F., Erbel, R., Erdmann, J., Eriksson, J. G., Farrall, M., Felix, S. B., Ferrannini, E., Ferrieres, J., Ford, I., Forouhi, N. G., Forrester, T., Franco, O. H., Gansevoort, R. T., Gejman, P. V., Gieger, C., Gottesman, O., Gudnason, V., Gyllensten, U., Hall, A. S., Harris, T. B., Hattersley, A. T., Hicks, A. A., Hindorff, L. A., Hingorani, A. D., Hofman, A., Homuth, G., Humphries, S. E., Hunt, S. C., Hypponen, E., Illig, T., Jacobs, K. B., Jarvelin, M., Joeckel, K., Johansen, B., Jousilahti, P., Jukema, J. W., Jula, A. M., Kaprio, J., Keinanen-Kiukaanniemi, S. M., Kiemeney, L. A., Knekt, P., Kooner, J. S., Kooperberg, C., Kovacs, P., Kraja, A. T., Kumari, M., Kuusisto, J., Lakka, T. A., Langenberg, C., Le Marchand, L., Lehtimaki, T., Lyssenko, V., Mannisto, S., Marette, A., Matise, T. C., McKenzie, C. A., McKnight, B., Moll, F. L., Morris, A. D., Morris, A. P., Murray, J. C., Nelis, M., Ohlsson, C., Oldehinkel, A. J., Ong, K. K., Madden, P. A. F., Pasterkamp, G., Peden, J. F., Peters, A., Postma, D. S., Pramstaller, P. P., Price, J. F., Qi, L., Raitakari, O. T., Rankinen, T., Rao, D. C., Rice, T. K., Ridker, P. M., Rioux, J. D., Ritchie, M. D., Rudan, I., Salomaa, V., Samani, N. J., Saramines, J., Sarzynski, M. A., Schunkert, H., Schwarz, P. E. H., Sever, P., Shuldiner, A. R., Sinisalo, J., Stolk, R. P., Strauch, K., Toenjes, A., Tregouet, D., Tremblay, A., Tremoli, E., Virtamo, J., Vohl, M., Voelker, U., Waeber, G., Willemsen, G., Witteman, J. C., Zillikens, M. C., Adair, L. S., Amouyel, P., Asselbergs, F. W., Assimes, T. L., Bochud, M., Boehm, B. O., Boerwinkle, E., Bornstein, S. R., Bottinger, E. P., Bouchard, C., Cauchi, S., Chambers, J. C., Chanock, S. J., Cooper, R. S., de Bakker, P. I. W., Dedoussis, G., Ferrucci, L., Franks, P. W., Froguel, P., Groop, L. C., Haiman, C. A., Hamsten, A., Hui, J., Hunter, D. J., Hveem, K., Kaplan, R. C., Kivimaki, M., Kuh, D., Laakso, M., Liu, Y., Martin, N. G., Maerz, W., Melbve, M., Metspalu, A., Moebus, S., Munroe, P. B., Njolstad, I., Oostra, B. A., Palmer, C. N. A., Pedersen, N. L., Perola, M., Perusse, L., Peters, U., Power, C., Quertermous, T., Rauramaa, R., Rivadeneira, F., Saaristo, T. E., Saleheen, D., Sattar, N., Schadt, E. E., Schlessinger, D., Slagboom, P. E., Snieder, H., Spector, T. D., Thorsteinsdottir, U. R., Stumvoll, M., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., van der Harst, P., Walker, M., Wallaschofski, H., Wareham, N. J., Watkins, H., Weir, D. R., Wichmann, H., Wilson, J. F., Zanen, P., Borecki, I. B., Deloukas, P., Fox, C. S., Heid, I. M., O'Connell, J. R., Strachan, D. P., Stefansson, K., van Duijri, C. M., Abecasis, G. R., Franke, L., Frayling, T. M., McCarthy, M. I., Visscher, P. M., Scherag, A., Willer, C. J., Boehnke, M., Mohlke, K. L., Lindgren, C. M., Beckmann, J. S., Barroso, I., North, K. E., Ingelsson, E., Hirschhorn, J. N., Loos, R. J. F. & Speliotes, E. K., 2015, In: NATURE. 518, 7538, p. 197-U401

Research output: Contribution to journal › Article › Academic › peer-review

3056 Citations (Scopus)

HDL re-examined

Hovingh, G. K., Rader, D. J. & Hegele, R. A., 2015, In: Current opinion in lipidology. 26, 2, p. 127-132

Research output: Contribution to journal › Review article › Academic › peer-review

33 Citations (Scopus)

High-dose atorvastatin is superior to moderate-dose simvastatin in preventing peripheral arterial disease

Stoekenbroek, R. M., Boekholdt, S. M., Fayyad, R., Laskey, R., Tikkanen, M. J., Pedersen, T. R. & Hovingh, G. K., 2015, In: Heart (British Cardiac Society). 101, 5, p. 356-362

Research output: Contribution to journal › Article › Academic › peer-review

33 Citations (Scopus)

Homozigot ailevi hiperkolesterolemi: klinisyenlerin taniyi ve klinik yönetimi geliştirmelerine yönelik yeni anlayişlar ve rehberlik. Avrupa Ateroskleroz Derneği'nin Ailevi Hiperkolesterolemi Üzerine Uzlaşi Paneli yazili görüşü

AUTHOR GROUP, 2015, In: Türk Kardiyoloji Derneği arşivi. 43, Suppl. 1, p. 1-14

Research output: Contribution to journal › Article › Academic › peer-review

2 Citations (Scopus)

Homozygous autosomal dominant hypercholesterolaemia: prevalence, diagnosis, and current and future treatment perspectives

Sjouke, B., Hovingh, G. K., Kastelein, J. J. P. & Stefanutti, C., 2015, In: Current opinion in lipidology. 26, 3, p. 200-209

Research output: Contribution to journal › Review article › Academic › peer-review

47 Citations (Scopus)

Homozygous autosomal dominant hypercholesterolaemia in the Netherlands: prevalence, genotype-phenotype relationship, and clinical outcome

Sjouke, B., Kusters, D. M., Kindt, I., Besseling, J., Defesche, J. C., Sijbrands, E. J. G., Roeters van Lennep, J. E., Stalenhoef, A. F. H., Wiegman, A., de Graaf, J., Fouchier, S. W., Kastelein, J. J. P. & Hovingh, G. K., 2015, In: European Heart journal. 36, 9, p. 560-565

Research output: Contribution to journal › Article › Academic › peer-review

362 Citations (Scopus)

Hypercholesterolaemia and hepatosplenomegaly: two manifestations of cholesteryl ester storage disease

Sjouke, B., van der Stappen, J. W. J., Groener, J. E. M., Pepping, A., Wevers, R. A., Gouw, A., Dikkeschei, L. D., Mijnhout, S., Hovingh, G. K. & Alleman, M. A., 2015, In: Netherlands journal of medicine. 73, 3, p. 129-132

Research output: Contribution to journal › Article › Academic › peer-review

11 Citations (Scopus)

Impact of statin therapy on coronary plaque composition: a systematic review and meta-analysis of virtual histology intravascular ultrasound studies

Banach, M., Serban, C., Sahebkar, A., Mikhailidis, D. P., Ursoniu, S., Ray, K. K., Rysz, J., Toth, P. P., Muntner, P., Mosteoru, S., García-García, H. M., Hovingh, G. K., Kastelein, J. J. P. & Serruys, P. W., 2015, In: BMC medicine. 13, 1, p. 229

Research output: Contribution to journal › Article › Academic › peer-review

172 Citations (Scopus)

Inhibition of PCSK9 with evolocumab in homozygous familial hypercholesterolaemia (TESLA Part B): a randomised, double-blind, placebo-controlled trial

AUTHOR GROUP, 2015, In: Lancet. 385, 9965, p. 341-350

Research output: Contribution to journal › Article › Academic › peer-review

608 Citations (Scopus)

Is Cholesteryl Ester Transfer Protein Inhibition an Effective Strategy to Reduce Cardiovascular Risk? CETP as a Target to Lower CVD Risk: Suspension of Disbelief?

Hovingh, G. K., Ray, K. K. & Boekholdt, S. M., 2015, In: Circulation. 132, 5, p. 433-440

Research output: Contribution to journal › Article › Academic › peer-review

25 Citations (Scopus)

Lipoprotein profiles in human heterozygote carriers of a functional mutation P297S in scavenger receptor class B1

Ljunggren, S. A., Levels, J. H. M., Hovingh, K., Holleboom, A. G., Vergeer, M., Argyri, L., Gkolfinopoulou, C., Chroni, A., Sierts, J. A., Kastelein, J. J., Kuivenhoven, J. A., Lindahl, M. & Karlsson, H., 2015, In: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. 1851, 12, p. 1587-1595

Research output: Contribution to journal › Article › Academic › peer-review

13 Citations (Scopus)

Myocardial infarction in a 36-year-old man with combined ABCA1 and APOA-1 deficiency

van Capelleveen, J. C., Kootte, R. S., Hovingh, G. K. & Bochem, A. E., 2015, In: Journal of clinical lipidology. 9, 3, p. 396-399

Research output: Contribution to journal › Editorial › Academic › peer-review

5 Citations (Scopus)

New Approaches in Detection and Treatment of Familial Hypercholesterolemia

Hartgers, M. L., Ray, K. K. & Hovingh, G. K., 2015, In: Current Cardiology Reports. 17, 12, p. 109

Research output: Contribution to journal › Review article › Academic › peer-review

20 Citations (Scopus)

New genetic loci link adipose and insulin biology to body fat distribution

AUTHOR GROUP, Lockes, A. E., Maegi, R., Kristiansson, K., Mangino, M., Leach, I. M., Medina-Gomez, C., Palmer, C. D., Pasko, D., Pechlivaniss, S., Peters, MJ., Prokopenko, I., Stancakova, A., Sung, Y. J., Tanakam, T., Teumer, A., van Vliet-Ostaptchouk, J. V., Yengo, L., Zhang, W., Albrecht, E., & 343 othersArnlov, J., Arscott, G. M., Bandinelli, S., Barrett, A., Bellis, C., Bennett, A. J., Berne, C., Blueher, M., Buhringer, S., Bonnet, F., Boettcher, Y., Bruinenberg, M., Carba, D. B., Caspersen, I. H., Clarke, R., Daw, E. W., Deelen, J., Deelman, E., Delgado, G., Doney, A. S. F., Eklund, N., Erdos, M. R., Estrada, K., Eury, E., Friedrichs, N., Garcia, M. E., Giedraitis, V., Gigante, B., Go, A. S., Golay, A., Grallert, H., Grammer, T. B., Graessler, J., Grewal, J., Groves, C. J., Haller, T., Hallmans, G., Hartman, C. A., Hassinen, M., Hayward, C., Heikkila, K., Herzig, K., Helmer, Q., Hillege, H. L., Holmen, O., Hunt, S. C., Isaacs, A., Ittermann, T., James, A. L., Johansson, I., Juliusdottir, T., Kalafati, I., Kinnunen, L., Koenig, W., Kooner, I. K., Kratzer, W., Lamina, C., Leander, K., Lee, N. R., Lichtner, P., Lind, L., Lindstrom, J., Lobbens, S., Lorentzon, M., Mach, F., Magnusson, P. K. E., Mahajan, A., McArdle, W. L., Menni, C., Merger, S., Mihailov, E., Milani, L., Mills, R., Moayyeri, A., Monda, K. L., Mooijaart, S. P., Muehleisen, T. W., Mulas, A., Mueller, G., Mueller-Nurasyid, M., Nagaraja, R., Nalls, M. A., Narisu, N., Glorioso, N., Nolte, I. M., Olden, M., Rayner, N. W., Renstrom, F., Ried, J. S., Robertson, N. R., Rose, L. M., Sanna, S., Scharnagl, H., Scholtens, S., Sennblad, B., Seufferlein, T., Sitlani, C. M., Smith, A. V., Stirrups, K., Stringham, H. M., Sundstrom, J., Swertz, M. A., Swift, A. J., Syvanen, A., Tayo, B. O., Thorand, B., Thorleifsson, G., Tomaschitz, A., Troffa, C., van Oort, F. V. A., Verweij, N., Vonk, J. M., Waite, L. L., Wennauer, R., Wilsgaard, T., Wojczynski, M. K., Wong, A., Zhang, Q., Zhao, J. H., Brennan, E. P., Choi, M., Eriksson, P., Folkersen, L., Franco-Cereceda, A., Gharavi, A. G., Hedman, A. K., Hivert, M., Huang, J., Kanoni, S., Karpe, F., Keildson, S., Kiryluk, K., Liang, L., Lifton, R. P., Ma, B., McKnight, A. J., McPherson, R., Metspalu, A., Min, J. L., Moffatt, M. F., Montgomery, G. W., Murabito, J. M., Nicholson, G., Nyholt, DR., Olsson, C., Perry, J. R. B., Reinmaa, E., Salem, R. M., Sandholm, N., Schadt, E. E., Scott, R. A., Stolk, L., Vallejo, E. E., Westra, H., Zondervan, K. T., Amouyel, P., Arveiler, D., Bakker, S. J. L., Beilby, J., Bergman, R. N., Blangero, J., Brown, M. J., Burnier, M., Campbell, H., Chakravarti, A., Chiness, P. S., Claudi-Boehmi, S., Collins, F. S., Crawford, D. C., Danesh, J., de Faire, U., de Geus, E. J. C., Doerr, M., Erbel, R., Eriksson, J. G., Farrall, M., Ferrannini, E., Ferrieres, J., Forouhi, N. G., Forrester, T., Franco, O. H., Gansevoort, R. T., Gieger, C., Gudnason, V., Haiman, C. A., Harris, T. B., Hattersley, A. T., Heliovaara, M., Hicks, A. A., Hingorani, A. D., Hoffmann, W., Hofman, A., Homuth, G., Humphries, S. E., Hyppoenen, E., Illig, T., Jarvelin, M., Johansen, B., Jousilahti, P., Jula, A. M., Kaprio, J., Kee, F., Keinanen-Kiukaanniemi, S. M., Kooner, J. S., Kooperberg, C., Kovacs, P., Kraja, A. T., Kumari, M., Kuulasmaa, K., Kuusisto, J., Lakka, T. A., Langenberg, C., Le Marchand, L., Lehtimaki, T., Lyssenko, V., Mannisto, S., Marette, A., Matise, T. C., McKenzie, C. A., McKnight, B., Musk, A. W., Mohlenkamp, S., Morris, A. D., Nelis, M., Ohlsson, C., Oldehinkel, A. J., Ong, K. K., Palmer, L. J., Penninx, B. W. J. H., Peters, A., Pramstaller, P. P., Raitakari, O. T., Rankinen, T., Rao, D. C., Rice, T. K., Ridker, P. M., Ritchie, M. D., Rudan, I., Salomaa, V., Samani, N. J., Saramies, J., Sarzynski, M. A., Schwarz, P. E. H., Shuldiner, A. R., Staessen, J. A., Steinthorsdottir, V., Stolk, R. P., Strauch, K., Toenjes, A., Tremblay, A., Tremoli, E., Vohl, M., Voelker, U., Vollenweider, P., Wilson, J. F., Witteman, J. C., Adair, L. S., Bochud, M., Boehm, B. O., Bornstein, S. R., Bouchard, C., Cauchi, S., Caulfield, M. J., Chambers, J. C., Chasman, D. I., Cooper, R. S., Dedoussis, G., Ferrucci, L., Froguel, P., Grabe, H., Hamsten, A., Hui, J., Hveem, K., Joeckel, K., Kivimaki, M., Kuh, D., Laakso, M., Liu, Y., Maerz, W., Munroe, P. B., Njolstad, I., Oostra, B. A., Palmer, C. N. A., Pedersen, N. L., Perola, M., Perusse, L., Peters, U., Power, C., Quertermous, T., Rauramaa, R., Rivadeneira, F., Saaristo, T. E., Saleheen, D., Sinisalo, J., Slagboom, P. E., Snieder, H., Spector, T. D., Thorsteinsdottir, U. R., Stumvoll, M., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., van der Harst, P., Veronesi, G., Walker, M., Wareham, N. J., Watkins, H., Wichmann, H., Abecasis, G. R., Assimes, T. L., Berndt, S. I., Boehnkes, M., Borecki, I. B., Deloukas, P., Franke, L., Frayling, T. M., Groop, L. C., Hunter, D. J., Kaplan, R. C., O'Connell, J. R., Qi, L., Schlessinger, D., Strachan, D. P., Stefansson, K., van Dujin, C. M., Willer, C. J., Visscher, P. M., Yang, J., Hirschhorn, J. N., Zillikens, M. C., McCarthy, M. I., Speliotes, E. K., North, K. E., Fox, C. S., Barroso, I., Franks, P. W., Ingelsson, E., Heid, I. M., Loos, R. J. F., Cupples, L. A., Morris, A. P., Lindgren, C. M. & Mohlke, K. L., 2015, In: NATURE. 518, 7538, p. 187-U378

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

1097 Citations (Scopus)

Non-high-density lipoprotein cholesterol: current status as cardiovascular marker

Verbeek, R., Hovingh, G. K. & Boekholdt, S. M., 2015, In: Current opinion in lipidology. 26, 6, p. 502-510

Research output: Contribution to journal › Review article › Academic › peer-review

66 Citations (Scopus)

ODYSSEY FH I and FH II: 78 week results with alirocumab treatment in 735 patients with heterozygous familial hypercholesterolaemia

Kastelein, J. J. P., Ginsberg, H. N., Langslet, G., Hovingh, G. K., Ceska, R., Dufour, R., Blom, D., Civeira, F., Krempf, M., Lorenzato, C., Zhao, J., Pordy, R., Baccara-Dinet, M. T., Gipe, D. A., Geiger, M. J. & Farnier, M., 2015, In: European Heart journal. 36, 43, p. 2996-3003

Research output: Contribution to journal › Article › Academic › peer-review

476 Citations (Scopus)

PCSK9 inhibition with evolocumab (AMG 145) in heterozygous familial hypercholesterolaemia (RUTHERFORD-2): a randomised, double-blind, placebo-controlled trial

AUTHOR GROUP, 2015, In: Lancet. 385, 9965, p. 331-340

Research output: Contribution to journal › Article › Academic › peer-review

633 Citations (Scopus)

PCSK9 inhibitors: Novel therapeutic agents for the treatment of hypercholesterolemia

Verbeek, R., Stoekenbroek, R. M. & Hovingh, G. K., 2015, In: European journal of pharmacology. 763, Part A, p. 38-47

Research output: Contribution to journal › Article › Academic › peer-review

34 Citations (Scopus)

Prevalence and management of familial hypercholesterolaemia in coronary patients: An analysis of EUROASPIRE IV, a study of the European Society of Cardiology

de Backer, G., Besseling, J., Chapman, J., Hovingh, G. K., Kastelein, J. J. P., Kotseva, K., Ray, K., Reiner, Ž., Wood, D. & de Bacquer, D., 2015, In: Atherosclerosis. 241, 1, p. 169-175

Research output: Contribution to journal › Article › Academic › peer-review

131 Citations (Scopus)

Reply: statin-induced low low-density lipoprotein cholesterol level: is lower better?

Boekholdt, S. M., Hovingh, G. K., Waters, D. D., Grundy, S. M. & Kastelein, J. J. P., 2015, In: Journal of the American College of Cardiology. 65, 1, p. 109

Research output: Contribution to journal › Comment/Letter to the editor › Academic

Statin-associated muscle symptoms: impact on statin therapy-European Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and Management

AUTHOR GROUP, 2015, In: European Heart journal. 36, 17, p. 1012-1022

Research output: Contribution to journal › Review article › Academic › peer-review

1049 Citations (Scopus)

Statin intolerance - an attempt at a unified definition. Position paper from an International Lipid Expert Panel

Banach, M., Rizzo, M., Toth, P. P., Farnier, M., Davidson, M. H., Al-Rasadi, K., Aronow, W. S., Athyros, V., Djuric, D. M., Ezhov, M. V., Greenfield, R. S., Hovingh, G. K., Kostner, K., Serban, C., Lighezan, D., Fras, Z., Moriarty, P. M., Muntner, P., Goudev, A., Ceska, R., & 11 othersNicholls, S. J., Broncel, M., Nikolic, D., Pella, D., Puri, R., Rysz, J., Wong, N. D., Bajnok, L., Jones, S. R., Ray, K. K. & Mikhailidis, D. P., 2015, In: Expert opinion on drug safety. 14, 6, p. 935-955

Research output: Contribution to journal › Review article › Academic › peer-review

109 Citations (Scopus)

Statin intolerance - an attempt at a unified definition. Position paper from an International Lipid Expert Panel

Banach, M., Rizzo, M., Toth, P. P., Farnier, M., Davidson, M. H., Al-Rasadi, K., Aronow, W. S., Athyros, V., Djuric, D. M., Ezhov, M. V., Greenfield, R. S., Hovingh, G. K., Kostner, K., Serban, C., Lighezan, D., Fras, Z., Moriarty, P. M., Muntner, P., Goudev, A., Ceska, R., & 11 othersNicholls, S. J., Broncel, M., Nikolic, D., Pella, D., Puri, R., Rysz, J., Wong, N. D., Bajnok, L., Jones, S. R., Ray, K. K. & Mikhailidis, D. P., 2015, In: Archives of medical science. 11, 1, p. 1-23

Research output: Contribution to journal › Article › Academic › peer-review

323 Citations (Scopus)

The effect of an apolipoprotein A-I-containing high-density lipoprotein-mimetic particle (CER-001) on carotid artery wall thickness in patients with homozygous familial hypercholesterolemia: The Modifying Orphan Disease Evaluation (MODE) study

Hovingh, G. K., Smits, L. P., Stefanutti, C., Soran, H., Kwok, S., de Graaf, J., Gaudet, D., Keyserling, C. H., Klepp, H., Frick, J., Paolini, J. F., Dasseux, J-L., Kastelein, J. J. P. & Stroes, E. S., 2015, In: American Heart Journal. 169, 5, p. 736-742.e1

Research output: Contribution to journal › Article › Academic › peer-review

61 Citations (Scopus)

The impact of LDLR function on fibroblast growth factor 21 levels

Besseling, J., Ong, K. L., Huijgen, R., Rye, K-A., Hovingh, G. K., Hutten, B. A. & Lambert, G., 2015, In: Atherosclerosis. 241, 2, p. 322-325

Research output: Contribution to journal › Article › Academic › peer-review

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

Winkler, T. W., Justice, A. E., Graff, M., Barata, L., Feitosa, M. F., Chu, S., Czajkowski, J., Esko, T., Fall, T., Kilpelainen, T. O., Lu, Y., Magi, R., Mihailov, E., Pers, T. H., Rueeger, S., Teumer, A., Ehret, G. B., Ferreira, T., Heard-Costa, N. L., Karjalainen, J., & 442 othersLagou, V., Mahajan, A., Neinast, M. D., Prokopenko, I., Simino, J., Teslovich, T. M., Jansen, R., Westra, H., White, C. C., Absher, D., Ahluwalia, T. S., Ahmad, S., Albrecht, E., Alves, A. C., Bragg-Gresham, J. L., Craen, A. J. M., Bis, J. C., Bonnefond, A., Boucher, G., Cadby, G., Cheng, Y., Chiang, C. W. K., Delgado, G., Demirkan, A., Dueker, N., Eklund, N., Eiriksdottir, G., Eriksson, J., Feenstra, B., Fischer, K., Frau, F., Galesloot, T. E., Geller, F., Goel, A., Gorski, M., Grammer, T. B., Gustafsson, S., Haitjema, S., Hottenga, J. J., Huffman, J. E., Jackson, A. U., Jacobs, K. B., Johansson, A., Kaakinen, M., Kleber, M. E., Lahti, J., Leach, I. M., Lehne, B., Lo, K. S., Lorentzon, M., Luan, J., Madden, P. A. F., Mangino, M., McKnight, B., Medina-Gomez, C., Monda, K. L., Montasser, M. E., Mueller, G., Mueller-Nurasyid, M., Nolte, I. M., Panoutsopoulou, K., Pascoe, L., Paternoster, L., Rayner, N. W., Renstrom, F., Rizzi, F., Rose, L. M., Ryan, K. A., Salo, P., Sanna, S., Scharnagl, H., Shi, J., Smith, A. V., Southam, L., Stancakova, A., Steinthorsdottir, V., Strawbridge, R. J., Sung, Y. J., Tachmazidou, I., Tanaka, T., Thorleifsson, G., Trompet, S., Pervjakova, N., Tyrer, J. P., Vandenput, L., van der Laan, S. W., van der Velde, N., van Setten, J., van Vliet-Ostaptchouk, J. V., Verweij, N., Vlachopoulou, E., Waite, L. L., Wang, S. R., Wang, Z., Wild, S. H., Willenborg, C., Wilson, J. F., Wong, A., Yang, J., Yengo, L., Yerges-Armstrong, L. M., Yu, L., Zhang, W., Zhao, J. H., Andersson, E. A., Bakker, S. J. L., Baldassarre, D., Banasik, K., Barcella, M., Barlassina, C., Bellis, C., Benaglio, P., Blangero, J., Blueher, M., Bonnet, F., Bonnycastle, L. L., Boyd, H. A., Bruinenberg, M., Buchman, A. S., Campbell, H., Chen, Y. I., Chines, P. S., Claudi-Boehm, S., Cole, J., Collins, F. S., de Geus, E. J. C., de Groot, L. C. P. G. M., Dimitriou, M., Duan, J., Enroth, S., Eury, E., Farmaki, A., Forouhi, N. G., Friedrich, N., Gejman, P. V., Gigante, B., Glorioso, N., Go, A. S., Gottesman, O., Graessler, J., Grallert, H., Grarup, N., Gu, Y., Broer, L., van der Ham, A. C., Hansen, T., Harris, T. B., Hartman, C. A., Hassinen, M., Hastie, N., Hattersley, A. T., Heath, A. C., Henders, A. K., Hernandez, D., Hillege, H., Holmen, O., Hovingh, K. G., Hui, J., Husemoen, L. L., Hutri-Kahonen, N., Hysi, P. G., Illig, T., de Jager, P. L., Jalilzadeh, S., Jorgensen, T., Jukema, J. W., Juonala, M., Kanoni, S., Karaleftheri, M., Khaw, K. T., Kinnunen, L., Kittner, S. J., Koenig, W., Kolcic, I., Kovacs, P., Krarup, N. T., Kratzer, W., Krueger, J., Kuh, D., Kumari, M., Kyriakou, T., Langenberg, C., Lannfelt, L., Lanzani, C., Lotay, V., Launer, L. J., Leander, K., Lindstrom, J., Linneberg, A., Liu, Y., Lobbens, S., Luben, R., Lyssenko, V., Mannisto, S., Magnusson, P. K., McArdle, W. L., Menni, C., Merger, S., Milani, L., Montgomery, G. W., Morris, A. P., Narisu, N., Nelis, M., Ong, K. K., Palotie, A., Perusse, L., Pichler, I., Pilia, M. G., Pouta, A., Rheinberger, M., Ribel-Madsen, R., Richards, M., Rice, K. M., Rice, T. K., Rivolta, C., Salomaa, V., Sanders, A. R., Sarzynski, M. A., Scholtens, S., Scott, R. A., Scott, W. R., Sebert, S., Sengupta, S., Sennblad, B., Seufferlein, T., Silveira, A., Slagboom, P. E., Smit, J. H., Sparso, T. H., Stirrups, K., Stolk, R. P., Stringham, H. M., Swertz, M. A., Swift, A. J., Syvanen, A., Tan, S., Thorand, B., Toenjes, A., Tremblay, A., Tsafantakis, E., van der Most, P. J., Voelker, U., Vohl, M., Vonk, J. M., Waldenberger, M., Walker, R. W., Wennauer, R., Widen, E., Willemsen, G., Wilsgaard, T., Wright, A. F., Zillikens, M. C., van Dijk, S. C., van Schoor, N. M., Asselbergs, F. W., Bakker, P. I. W., Beckmann, J. S., Beilby, J., Bennett, D. A., Bergman, R. N., Bergmann, S., Boeger, C. A., Boehm, B. O., Boerwinkle, E., Boomsma, D. I., Bornstein, S. R., Bottinger, E. P., Bouchard, C., Chambers, J. C., Chanock, S. J., Chasman, D. I., Cucca, F., Cusi, D., Dedoussis, G., Erdmann, J., Eriksson, J. G., Evans, D. A., de Faire, U., Farrall, M., Ferrucci, L., Ford, I., Franke, L., Franks, P. W., Froguel, P., Gansevoort, R. T., Gieger, C., Gronberg, H., Gudnason, V., Gyllensten, U., Hall, P., Hamsten, A., van der Harst, P., Hayward, C., Heliovaara, M., Hengstenberg, C., Hicks, A. A., Hingorani, A., Hofman, A., Hu, F., Huikuri, H. V., Hveem, K., James, A. L., Jordan, J. M., Jula, A., Kaehoenen, M., Kajantie, E., Kathiresan, S., Kiemeney, L. A. L. M., Kivimaki, M., Knekt, P. B., Koistinen, H. A., Kooner, J. S., Koskinen, S., Kuusisto, J., Maerz, W., Martin, N. G., Laakso, M., Lakka, T. A., Lehtimaki, T., Lettre, G., Levinson, D. F., Lind, L., Lokki, M., Mantyselka, P., Melbye, M., Metspalu, A., Mitchell, B. D., Moll, F. L., Murray, J. C., Musk, A. W., Nieminen, M. S., Njolstad, I., Ohlsson, C., Oldehinkel, A. J., Oostra, B. A., Palmer, L. J., Pankow, J. S., Pasterkamp, G., Pedersen, N. L., Pedersen, O., Penninx, B. W. J. H., Perola, M., Peters, A., Polasek, O., Pramstaller, P. P., Psaty, B. M., Qi, L., Quertermous, T., Raitakari, O. T., Rankinen, T., Rauramaa, R., Ridker, P. M., Rioux, J. D., Rivadeneira, F., Rotter, J. I., Rudan, I., den Ruijter, H. M., Saltevo, J., Sattar, N., Schunkert, H., Schwarz, P. E. H., Shuldiner, A. R., Sinisalo, J., Snieder, H., Sorensen, T. I. A., Spector, T. D., Staessen, J. A., Stefania, B., Thorsteinsdottir, U., Stumvoll, M., Tardif, J., Tremoli, E., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., Verbeek, A. L. M., Vermeulen, S. H., Viikari, J. S., Vitart, V., Voelzke, H., Vollenweider, P., Waeber, G., Walker, M., Wallaschofski, H., Wareham, N. J., Watkins, H., Zeggini, E., Chakravarti, A., Clegg, D. J., Cupples, L. A., Gordon-Larsen, P., Jaquish, C. E., Rao, D. C., Abecasis, G. R., Assimes, T. L., Barroso, I., Berndt, S. I., Boehnke, M., Deloukas, P., Fox, C. S., Groop, L. C., Hunter, D. J., Ingelsson, E., Kaplan, R. C., McCarthy, M. I., Mohlke, K. L., O'Connell, J. R., Schlessinger, D., Strachan, D. P., Stefansson, K., van Duijn, C. M., Hirschhorn, J. N., Lindgren, C. M., Heid, I. M., North, K. E., Borecki, I. B., Kutalik, Z., Loos, R. J. F., Kilpeläinen, T. O., Mägi, R., Rüeger, S., Müller, G., Müller-Nurasyid, M., Renström, F., Stančáková, A., Blüher, M., Gräßler, J., Hutri-Kähönen, N., Jørgensen, T., Krüger, J., Lindström, J., Männistö, S., Sparsø, T. H., Syvänen, A-C., Grönberg, H., Heliövaara, M., Kähönen, M., Lehtimäki, T., Mäntyselkä, P., Njølstad, I., Polašek, O. & Sørensen, T. I. A., 2015, In: PLoS genetics. 11, 10, p. e1005378 e1005378.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

267 Citations (Scopus)

Vascular risk factors, vascular disease, lipids and lipid targets in patients with familial dysbetalipoproteinemia: a European cross-sectional study

Koopal, C., Retterstøl, K., Sjouke, B., Hovingh, G. K., Ros, E., de Graaf, J., Dullaart, R. P. F., Bertolini, S. & Visseren, F. L. J., 2015, In: Atherosclerosis. 240, 1, p. 90-97

Research output: Contribution to journal › Article › Academic › peer-review

40 Citations (Scopus)

2014

Abnormal hemostatic parameters in patients with myocardial infarction but angiographically normal coronary arteries

Maiwald, S., Oey, R. C., Sivapalaratnam, S., Bakhtiari, K., Hovingh, G. K., Basart, D. C. G., Trip, M. D. & Dallinga-Thie, G. M., 2014, In: International journal of cardiology. 174, 3, p. 734-735

Research output: Contribution to journal › Comment/Letter to the editor › Academic

Adrenal Function in females with low plasma HDL-C due to mutations in ABCA1 and LCAT

Bochem, A. E., Holleboom, A. G., Romijn, J. A., Hoekstra, M., Dallinga, G. M., Motazacker, M. M., Hovingh, G. K., Kuivenhoven, J. A. & Stroes, E. S. G., 2014, In: PLOS ONE. 9, 5, p. e90967

Research output: Contribution to journal › Article › Academic › peer-review

12 Citations (Scopus)

ApoA-I mutations, L202P and K131del, in HDL from heterozygotes with low HDL-C

Ljunggren, S., Levels, J. H. M., Turkina, M. V., Sundberg, S., Bochem, A. E., Hovingh, K., Holleboom, A. G., Lindahl, M., Kuivenhoven, J. A. & Karlsson, H., 2014, In: Proteomics. Clinical applications. 8, 3-4, p. 241-250

Research output: Contribution to journal › Article › Academic › peer-review

5 Citations (Scopus)

Common genetic variants do not associate with CAD in familial hypercholesterolemia

van Iperen, E. P. A., Sivapalaratnam, S., Boekholdt, S. M., Hovingh, G. K., Maiwald, S., Tanck, M. W., Soranzo, N., Stephens, J. C., Sambrook, J. G., Levi, M., Ouwehand, W. H., Kastelein, J. J., Trip, M. D. & Zwinderman, A. H., 2014, In: European journal of human genetics. 22, 6, p. 809-813

Research output: Contribution to journal › Article › Academic › peer-review

4 Citations (Scopus)

Defining the role of common variation in the genomic and biological architecture of adult human height

AUTHOR GROUP, Kleber, M. E., Kristiansson, K., Lim, U., Helmer, Q., Boomsma, D. I., Saleheen, D., Schlessinger, D., Slagboom, P. E., Snieder, H., Spector, T. D., Strauch, K., Stumvoll, M., Tuomilehto, J., Uusitupa, M., van der Harst, P., Völzke, H., Walker, M., Wareham, N. J., Watkins, H., & 39 othersWichmann, H. E., Wilson, J. F., Zanen, P., Deloukas, P., Heid, I. M., Lindgren, C. M., Mohlke, K. L., Speliotes, E. K., Thorsteinsdottir, U., Barroso, I., Fox, C. S., North, K. E., Strachan, D. P., Beckmann, J. S., Berndt, S. I., Boehnke, M., Borecki, I. B., McCarthy, M. I., Metspalu, A., Smit, J. H., Pilz, S., van Schoor, N. M., Stefansson, K., Uitterlinden, A. G., van Duijn, C. M., Franke, L., Willer, C. J., Price, A. L., Lettre, G., Loos, R. J. F., Weedon, M. N., Ingelsson, E., O'Connell, J. R., Abecasis, G. R., Chasman, D. I., Goddard, M. E., Visscher, P. M., Hirschhorn, J. N. & Frayling, T. M., 2014, In: Nature Genetics. 46, 11, p. 1173-1186 14 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

1295 Citations (Scopus)

Distribution and medical impact of loss-of-function variants in the Finnish founder population

Lim, E. T., Würtz, P., Havulinna, A. S., Palta, P., Tukiainen, T., Rehnström, K., Esko, T., Mägi, R., Inouye, M., Lappalainen, T., Chan, Y., Salem, R. M., Lek, M., Flannick, J., Sim, X., Manning, A., Ladenvall, C., Bumpstead, S., Hämäläinen, E., Aalto, K., & 40 othersMaksimow, M., Salmi, M., Blankenberg, S., Ardissino, D., Shah, S., Horne, B., McPherson, R., Hovingh, G. K., Reilly, M. P., Watkins, H., Goel, A., Farrall, M., Girelli, D., Reiner, A. P., Stitziel, N. O., Kathiresan, S., Gabriel, S., Barrett, J. C., Lehtimäki, T., Laakso, M., Groop, L., Kaprio, J., Perola, M., McCarthy, M. I., Boehnke, M., Altshuler, D. M., Lindgren, C. M., Hirschhorn, J. N., Metspalu, A., Freimer, N. B., Zeller, T., Jalkanen, S., Koskinen, S., Raitakari, O., Durbin, R., MacArthur, D. G., Salomaa, V., Ripatti, S., Daly, M. J. & Palotie, A., 2014, In: PLoS genetics. 10, 7, p. e1004494

Research output: Contribution to journal › Article › Academic › peer-review

283 Citations (Scopus)

eNOS activation by HDL is impaired in genetic CETP deficiency

Gomaraschi, M., Ossoli, A., Pozzi, S., Nilsson, P., Cefalù, A. B., Averna, M., Kuivenhoven, J. A., Hovingh, G. K., Veglia, F., Franceschini, G. & Calabresi, L., 2014, In: PLOS ONE. 9, 5, p. e95925

Research output: Contribution to journal › Article › Academic › peer-review

32 Citations (Scopus)

Eprotirome in patients with familial hypercholesterolaemia (the AKKA trial): a randomised, double-blind, placebo-controlled phase 3 study

Sjouke, B., Langslet, G., Ceska, R., Nicholls, S. J., Nissen, S. E., Öhlander, M., Ladenson, P. W., Olsson, A. G., Hovingh, G. K. & Kastelein, J. J. P., 2014, In: Lancet. Diabetes and endocrinology. 2, 6, p. 455-463

Research output: Contribution to journal › Article › Academic › peer-review

85 Citations (Scopus)

Gene-centric Meta-analysis in 87,736 Individuals of European Ancestry Identifies Multiple Blood-Pressure-Related Loci

Tragante, V., Barnes, M. R., Ganesh, S. K., Lanktree, M. B., Guo, W., Franceschini, N., Smith, E. N., Johnson, T., Holmes, M. V., Padmanabhan, S., Karczewski, K. J., Almoguera, B., Barnard, J., Baumert, J., Chang, Y. P. C., Elbers, C. C., Farrall, M., Fischer, M. E., Gaunt, T. R., Gho, J. M. I. H., & 116 othersGieger, C., Goel, A., Gong, Y., Isaacs, A., Kleber, M. E., Leach, I. M., McDonough, C. W., Meijs, M. F. L., Melander, O., Nelson, C. P., Nolte, I. M., Pankratz, N., Price, T. S., Shaffer, J., Shah, S., Tomaszewski, M., van der Most, P. J., van Iperen, E. P. A., Vonk, J. M., Witkowska, K., Wong, C. O. L., Zhang, L., Beitelshees, A. L., Berenson, G. S., Bhatt, D. L., Brown, M., Burt, A., Cooper-DeHoff, R. M., Connell, J. M., Cruickshanks, K. J., Curtis, S. P., Davey-Smith, G., Delles, C., Gansevoort, R. T., Guo, X. Q., Haiqing, S., Hastie, C. E., Hofker, M. H., Hovingh, G. K., Kim, D. S., Kirkland, S. A., Klein, B. E., Klein, R., Li, Y. R., Maiwald, S., Newton-Cheh, C., O'Brien, E. T., Onland-Moret, N. C., Palmas, W., Parsa, A., Penninx, B. W., Pettinger, M., Vasan, R. S., Ranchalis, J. E., Ridker, P. M., Rose, L. M., Sever, P., Shimbo, D., Steele, L., Stolk, R. P., Thorand, B., Trip, M. D., van Duijn, C. M., Verschuren, W. M., Wijmenga, C., Wyatt, S., Young, J. H., Zwinderman, A. H., Bezzina, C. R., Boerwinkle, E., Casas, J. P., Caulfield, M. J., Chakravarti, A., Chasman, D. I., Davidson, K. W., Doevendans, P. A., Dominiczak, A. F., FitzGerald, G. A., Gums, J. G., Munroe, P. B., Keating, B. J., Fornage, M., Hakonarson, H., Halder, I., Hillege, H. L., Illig, T., Jarvik, G. P., Johnson, J. A., Kastelein, J. J. P., Koenig, W., Kumari, M., März, W., Murray, S. S., O'Connell, J. R., Oldehinkel, A. J., Pankow, J. S., Rader, D. J., Redline, S., Reilly, M. P., Schadt, E. E., Kottke-Marchant, K., Snieder, H., Snyder, M., Stanton, A. V., Tobin, M. D., Uitterlinden, A. G., van der Harst, P., van der Schouw, Y. T., Samani, N. J., Watkins, H., Johnson, A. D., Reiner, A. P., Zhu, X., de Bakker, P. I. W., Levy, D. & Asselbergs, F. W., 2014, In: American journal of human genetics. 94, 3, p. 349-360

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

140 Citations (Scopus)

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

AUTHOR GROUP, 2014, In: Nature Genetics. 46, 3, p. 234-244

Research output: Contribution to journal › Article › Academic › peer-review

817 Citations (Scopus)

HDL and cardiovascular disease

Rader, D. J. & Hovingh, G. K., 2014, In: Lancet. 384, 9943, p. 618-625

Research output: Contribution to journal › Article › Academic › peer-review

484 Citations (Scopus)

Gerard Hovingh

Research output

Search results