Mariëlle van Breemen

Research output

Research output per year 2002 2005 2007 2011 2017 2020 2021 2023

• 21 Article
• 2 Chapter
• 1 Editorial

Research output per year

Research output per year

Search results

• 2023

  Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions

  Caniels, T. G., Medina-Ramírez, M., Zhang, J., Sarkar, A., Kumar, S., LaBranche, A., Derking, R., Allen, J. D., Snitselaar, J. L., Capella-Pujol, J., Sánchez, I. D. M., Yasmeen, A., Diaz, M., Aldon, Y., Bijl, T. P. L., Venkatayogi, S., Martin Beem, J. S., Newman, A., Jiang, C., Lee, W-H., & 18 othersPater, M., Burger, J. A., van Breemen, M. J., de Taeye, S. W., Rantalainen, K., LaBranche, C., Saunders, K. O., Montefiori, D., Ozorowski, G., Ward, A. B., Crispin, M., Moore, J. P., Klasse, P. J., Haynes, B. F., Wilson, I. A., Wiehe, K., Verkoczy, L. & Sanders, R. W., 18 Apr 2023, In: Cell Reports Medicine. 4, 4, 101003.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  6 Citations (Scopus)
• 2021

  COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models

  Maisonnasse, P., Aldon, Y., Marc, A., Marlin, R., Dereuddre-Bosquet, N., Kuzmina, N. A., Freyn, A. W., Snitselaar, J. L., Gonçalves, A., Caniels, T. G., Burger, J. A., Poniman, M., Bontjer, I., Chesnais, V., Diry, S. G., Iershov, A., Ronk, A. J., Jangra, S., Rathnasinghe, R., Brouwer, P. J. M., & 31 othersBijl, T. P. L., van Schooten, J., Brinkkemper, M., Liu, H., Yuan, M., Mire, C. E., van Breemen, M. J., Contreras, V., Naninck, T., Lemaître, J., Kahlaoui, N., Relouzat, F., Chapon, C., Ho Tsong Fang, R., McDanal, C., Osei-Twum, M., St-Amant, N., Gagnon, L., Montefiori, D. C., Wilson, I. A., Ginoux, E., de Bree, G. J., García-Sastre, A., Schotsaert, M., Coughlan, L., Bukreyev, A., van der Werf, S., Guedj, J. R., Sanders, R. W., van Gils, M. J. & le Grand, R., 1 Dec 2021, In: Nature communications. 12, 1, 6097.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  27 Citations (Scopus)

• Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection

  Brouwer, P. J. M., Brinkkemper, M., Maisonnasse, P., Dereuddre-Bosquet, N., Grobben, M., Claireaux, M., de Gast, M., Marlin, R., Chesnais, V., Diry, S. G., Allen, J. D., Watanabe, Y., Giezen, J. M., Kerster, G., Turner, H. L., van der Straten, K., van der Linden, C. A., Aldon, Y., Naninck, T., Bontjer, I., & 27 othersBurger, J. A., Poniman, M., Mykytyn, A. Z., Okba, N. M. A., Schermer, E. E., van Breemen, M. J., Ravichandran, R., Caniels, T. G., van Schooten, J., Kahlaoui, N., Contreras, V., Lemaître, J., Chapon, C., Fang, R. H. T., Villaudy, J., Sliepen, K., van der Velden, Y. U., Haagmans, B. L., de Bree, G. J., Ginoux, E., Ward, A. B., Crispin, M., King, N. P., van der Werf, S., van Gils, M. J., le Grand, R. & Sanders, R. W., 4 Mar 2021, In: Cell. 184, 5, p. 1188-1200.e19 36 p., 365726.

  Research output: Contribution to journal › Article › Academic

  Open Access
  114 Citations (Scopus)
• 2020

  Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

  Cottrell, C. A., van Schooten, J., Bowman, C. A., Yuan, M., Oyen, D., Shin, M., Morpurgo, R., van der Woude, P., van Breemen, M., Torres, J. L., Patel, R., Gross, J., Sewall, L. M., Copps, J., Ozorowski, G., Nogal, B., Sok, D., Rakasz, E. G., Labranche, C., Vigdorovich, V., & 11 othersChristley, S., Carnathan, D. G., Sather, D. N., Montefiori, D., Silvestri, G., Burton, D. R., Moore, J. P., Wilson, I. A., Sanders, R. W., Ward, A. B. & van Gils, M. J., 1 Aug 2020, In: PLoS pathogens. 16, 8, e1008753.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  42 Citations (Scopus)

• Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

  Brouwer, P. J. M., Caniels, T. G., van der Straten, K., Snitselaar, J. L., Aldon, Y., Bangaru, S., Torres, J. L., Okba, N. M. A., Claireaux, M., Kerster, G., Bentlage, A. E. H., van Haaren, M. M., Guerra, D., Burger, J. A., Schermer, E. E., Verheul, K. D., van der Velde, N., van der Kooi, A., van Schooten, J., van Breemen, M. J., & 13 othersBijl, T. P. L., Sliepen, K., Aartse, A., Derking, R., Bontjer, I., Kootstra, N. A., Joost Wiersinga, W., Vidarsson, G., Haagmans, B. L., Ward, A. B., de Bree, G. J., Sanders, R. W. & van Gils, M. J., 7 Aug 2020, In: Science. 369, 6504, p. 643-650 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  772 Citations (Scopus)
• 2019

  Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence

  Sliepen, K., Han, B. W., Bontjer, I., Mooij, P., Garces, F., Behrens, A-J., Rantalainen, K., Kumar, S., Sarkar, A., Brouwer, P. J. M., Hua, Y., Tolazzi, M., Schermer, E., Torres, J. L., Ozorowski, G., van der Woude, P., de la Peña, A. T., van Breemen, M. J., Camacho-Sánchez, J. M., Burger, J. A., & 15 othersMedina-Ramírez, M., González, N., Alcami, J., LaBranche, C., Scarlatti, G., van Gils, M. J., Crispin, M., Montefiori, D. C., Ward, A. B., Koopman, G., Moore, J. P., Shattock, R. J., Bogers, W. M., Wilson, I. A. & Sanders, R. W., 2019, In: Nature communications. 10, 1, 2355.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  92 Citations (Scopus)
• 2018

  Variable domain N-linked glycans acquired during antigen-specific immune responses can contribute to immunoglobulin G antibody stability

  van de Bovenkamp, F. S., Derksen, N. I. L., van Breemen, M. J., de Taeye, S. W., Ooijevaar-de Heer, P., Sanders, R. W. & Rispens, T., 2018, In: Frontiers in immunology. 9, APR, 740.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  35 Citations (Scopus)
• 2017

  A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human-type receptors

  de Vries, R. P., Tzarum, N., Peng, W., Thompson, A. J., Ambepitiya Wickramasinghe, I. N., de la Pena, A. T. T., van Breemen, M. J., Bouwman, K. M., Zhu, X., McBride, R., Yu, W., Sanders, R. W., Verheije, M. H., Wilson, I. A. & Paulson, J. C., 2017, In: EMBO molecular medicine. 9, 9, p. 1314-1325

  Research output: Contribution to journal › Article › Academic › peer-review
  37 Citations (Scopus)

• Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo

  Medina-Ramírez, M., Garces, F., Escolano, A., Skog, P., de Taeye, S. W., del Moral-Sanchez, I., McGuire, A. T., Yasmeen, A., Behrens, A-J., Ozorowski, G., van den Kerkhof, T. L. G. M., Freund, N. T., Dosenovic, P., Hua, Y., Gitlin, A. D., Cupo, A., van der Woude, P., Golabek, M., Sliepen, K., Blane, T., & 13 othersKootstra, N., van Breemen, M. J., Pritchard, L. K., Stanfield, R. L., Crispin, M., Ward, A. B., Stamatatos, L., Klasse, P. J., Moore, J. P., Nemazee, D., Nussenzweig, M. C., Wilson, I. A. & Sanders, R. W., 2017, In: Journal of Experimental Medicine. 214, 9, p. 2573-2590

  Research output: Contribution to journal › Article › Academic › peer-review
  117 Citations (Scopus)

• Three mutations switch H7N9 influenza to human-type receptor specificity

  de Vries, R. P., Peng, W., Grant, O. C., Thompson, A. J., Zhu, X., Bouwman, K. M., de la Pena, A. T. T., van Breemen, M. J., Ambepitiya Wickramasinghe, I. N., de Haan, C. A. M., Yu, W., McBride, R., Sanders, R. W., Woods, R. J., Verheije, M. H., Wilson, I. A. & Paulson, J. C., 2017, In: PLoS pathogens. 13, 6, p. e1006390

  Research output: Contribution to journal › Article › Academic › peer-review
  78 Citations (Scopus)
• 2015

  HIV-1 neutralizing antibodies induced by native-like envelope trimers

  Sanders, R. W., van Gils, M. J., Derking, R., Sok, D., Ketas, T. J., Burger, J. A., Ozorowski, G., Cupo, A., Simonich, C., Goo, L., Arendt, H., Kim, H. J., Lee, J. H., Pugach, P., Williams, M., Debnath, G., Moldt, B., van Breemen, M. J., Isik, G., Medina-Ramírez, M., & 17 othersBack, J. W., Koff, W. C., Julien, J-P., Rakasz, E. G., Seaman, M. S., Guttman, M., Lee, K. K., Klasse, P. J., Labranche, C., Schief, W. R., Wilson, I. A., Overbaugh, J., Burton, D. R., Ward, A. B., Montefiori, D. C., Dean, H. & Moore, J. P., 2015, In: Science. 349, 6244, p. aac4223-154

  Research output: Contribution to journal › Article › Academic › peer-review
  409 Citations (Scopus)
• 2011

  Reduction of elevated plasma globotriaosylsphingosine in patients with classic Fabry disease following enzyme replacement therapy

  van Breemen, M. J., Rombach, S. M., Dekker, N., Poorthuis, B. J., Linthorst, G. E., Zwinderman, A. H., Breunig, F., Wanner, C., Aerts, J. M. & Hollak, C. E., 2011, In: Biochimica et Biophysica Acta-Molecular Basis of Disease. 1812, 1, p. 70-76

  Research output: Contribution to journal › Article › Academic › peer-review
  125 Citations (Scopus)
• 2009

  Different dose-dependent correction of MIP-1beta and chitotriosidase during initial enzyme replacement therapy

  van Breemen, M. J., de Fost, M., Maas, M., Wiersma, M. G., Hollak, C. E. M., Poll, L. W., vom Dahl, S., Boot, R. G. & Aerts, J. M. F. G., 2009, In: Journal of Inherited Metabolic Disease. 32, 2, p. 274-279

  Research output: Contribution to journal › Article › Academic › peer-review
  6 Citations (Scopus)
• 2008

  Potential efficacy of enzyme replacement and substrate reduction therapy in three siblings with Gaucher disease type III

  Cox-Brinkman, J., van Breemen, M. J., van Maldegem, B. T., Bour, L., Donker, W. E., Hollak, C. E. M., Wijburg, F. A. & Aerts, J. M. F. G., 2008, In: Journal of Inherited Metabolic Disease. 31, 6, p. 745-752

  Research output: Contribution to journal › Article › Academic › peer-review
  34 Citations (Scopus)
• 2007

  Increased plasma macrophage inflammatory protein (MIP)-1 alpha and MIP-1 beta levels in type 1 Gaucher disease

  van Breemen, M. J., de Fost, M., Voerman, J. S. A., Laman, J. D., Boot, R. G., Maas, M., Hollak, C. E. M., Aerts, J. M. & Rezaee, F., 2007, In: Biochimica et Biophysica Acta-Molecular Basis of Disease. 1772, 7, p. 788-796

  Research output: Contribution to journal › Article › Academic › peer-review
  96 Citations (Scopus)

• The Dutch Fabry cohort: diversity of clinical manifestations and Gb3 levels

  Vedder, A. C., Linthorst, G. E., van Breemen, M. J., Groener, J. E. M., Bemelman, F. J., Strijland, A., Mannens, M. M. A. M., Aerts, J. M. F. G. & Hollak, C. E. M., 2007, In: Journal of Inherited Metabolic Disease. 30, 1, p. 68-78

  Research output: Contribution to journal › Article › Academic › peer-review
  159 Citations (Scopus)
• 2005

  Identification and use of biomarkers in Gaucher disease and other lysosomal storage diseases

  Aerts, J. M. F. G., Hollak, C. E. M., van Breemen, M., Maas, M., Groener, J. E. M. & Boot, R. G., 2005, In: Acta paediatrica (Oslo, Norway. 94, Suppl. 447, p. 43-46; discussion 37-8

  Research output: Contribution to journal › Article › Academic › peer-review
  63 Citations (Scopus)

• The blood-brain barrier and treatment of lysosomal storage disease

  Aerts, J. M. F. G., van Breemen, M. J., Bussink, A. P., Brinkman, J., Hollak, C. E. M., Langeveld, M., Linthorst, G. E., Vedder, A. C. & de Fost, M., 2005, In: INT CONGRESS SERIES. 1277, p. 19-31

  Research output: Contribution to journal › Article › Academic › peer-review

  4 Citations (Scopus)
• 2004

  Marked elevation of the chemokine CCL18/PARC in Gaucher disease: a novel surrogate marker for assessing therapeutic intervention

  Boot, R. G., Verhoek, M., de Fost, M., Hollak, C. E. M., Maas, M., Bleijlevens, B., van Breemen, M. J., van Meurs, M., Boven, L. A., Laman, J. D., Moran, M. T., Cox, T. M. & Aerts, J. M. F. G., 2004, In: Blood. 103, 1, p. 33-39

  Research output: Contribution to journal › Article › Academic › peer-review
  274 Citations (Scopus)
• 2003

  Amyloid beta plaque-associated proteins C1q and SAP enhance the Abeta1-42 peptide-induced cytokine secretion by adult human microglia in vitro

  Veerhuis, R., van Breemen, M. J., Hoozemans, J. M., Morbin, M., Ouladhadj, J., Tagliavini, F., Eikelenboom, P. & Van Breemen, MJ., Feb 2003, In: Acta Neuropathologica. 105, 2, p. 135-144

  Research output: Contribution to journal › Article › Academic › peer-review
  123 Citations (Scopus)
• 2002

  UVB irradiation of normal human skin favors the development of type-2 T-cells in vivo and in primary dermal cell cultures

  Di Nuzzo, S., Sylva-Steenland, R. M. R., Koomen, C. W., Nakagawa, S., van Breemen, M., de Rie, M. A., Das, P. K., Bos, J. D. & Teunissen, M. B. M., 2002, In: Photochemistry and photobiology. 76, 3, p. 301-309

  Research output: Contribution to journal › Article › Academic › peer-review
  11 Citations (Scopus)