Projects per year
Personal profile
Research interests
Renee Schreurs is a postdoctoral fellow in the Autophagy-directed Immunity lab headed by dr. Carla Ribeiro at the Department of Experimental Immunology, Amsterdam UMC (location AMC). She holds a MSc in Neuroscience and completed a PhD on the development of mucosal T cell immunity in the early-life intestine.
Within dr. Ribeiro's lab, Renee's current research focuses on investigating the impact of genetic variation in autophagy pathways on T cell functionality in the context of viral infections such as HIV-1. Additionally, Renee studies the impact of autophagy and extracellular vescicles on intestinal barrier integrity and inflammation using advanced organoid and organoid-immune cell co-culture models through partnerships with the Gutvibrations consortium and Emma Children's Hospital.
Ultimately, the Autophagy-directed Immunity lab aims to harness the therapeutic potential of targeting autophagy mechanisms to intervene with HIV-1, Dengue virus, and SARS-CoV-2 infections.
Specialisation
T cell immunity, intestinal inflammation, mucosal immune system, cell & organoid culture, autophagy, neuroscience, fetal and pediatric immunity, HIV-1
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 2 Active
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van Goudoever J.B.: Nutrition and Growth
van Goudoever, H. B., Akkermans, M. D., An, N., Beukers, F., Colenbrander, A. A., Gaasterland, C. M. W., Gigengack, M. R., van Ham, K., van Harskamp, D., Ingelse, S. A., Mank, E., Nieuwenhuijse, M. M., Oosterink, J. E., Schoonenboom, J. E., Schreurs, R. R. C. E., Zaal - Schuller, I. H., van Veenendaal, N. R. & Wijngaarde, R. O.
1/05/2013 → …
Project: Research
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Kuijpers T.W.: Infection and inflammation: on the crossroad of hematology and immunology
Aarts, C. E. M., de Back, D. Z., Barendregt, A. M., van Beek, A. E., de Blauw, D., Blokhuis, C., Bouva, M. J., Bruggeman, C. W., Bruning, A. H. L., Dalimot, J. J., Dietz, S. M., van de Geer, A., van Gulik, C. C., Gunnink, S. F., Keizer, S. M. P. D., Klaassen, I. L. M., Meinderts, S. M., Nagelkerke, S. Q., Pouw, R. B., van Rees, D. J., Scheenstra, M. R., Schonenberg, D., Schreurs, R. R. C. E., Sins, J. W. R. W. R., Stokhuijzen, E., Treffers, L. W., Tuijnenburg, P., Kuijpers, T., Boele van Hensbroek, M., Fijnvandraat, K., Pajkrt, D., van Rossum, M. A. J. & Hemke, R.
1/01/2006 → …
Project: Research
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CXCR5+PD-1++ CD4+ T cells colonize infant intestines early in life and promote B cell maturation
Jordan-Paiz, A., Martrus, G., Steinert, F. L., Kaufmann, M., Sagebiel, A. F., Schreurs, R. R. C. E., Rechtien, A., Baumdick, M. E., Jung, J. M., Möller, K. J., Wegner, L., Grüttner, C., Richert, L., Thünauer, R., Schroeder-Schwarz, J., van Goudoever, J. B., Geijtenbeek, T. B. H., Altfeld, M., Pals, S. T., Perez, D., & 9 others, Feb 2023, In: Cellular & molecular immunology. 20, 2, p. 201-213 13 p.Research output: Contribution to journal › Article › Academic › peer-review
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Autophagy-enhancing drugs limit mucosal HIV-1 acquisition and suppress viral replication ex vivo
Cloherty, A. P. M., van Teijlingen, N. H., Eisden, T-J. T. H. D., van Hamme, J. L., Rader, A. G., Geijtenbeek, T. B. H., Schreurs, R. R. C. E. & Ribeiro, C. M. S., 1 Dec 2021, In: Scientific reports. 11, 1, 4767.Research output: Contribution to journal › Article › Academic › peer-review
Open Access8 Citations (Scopus) -
Development of intestinal immunity: Spilling the guts on T cell maturation and inflammation in the early-life intestine
Schreurs, R. R. C. E., 2021, 197 p.Research output: Thesis › Phd-Thesis - Research and graduation internal
Open Access -
Intestinal CD8+ T cell responses are abundantly induced early in human development but show impaired cytotoxic effector capacities
Schreurs, R. R. C. E., Sagebiel, A. F., Steinert, F. L., Highton, A. J., Klarenbeek, P. L., Drewniak, A., Bakx, R., The, S. M. L., Ribeiro, C. M. S., Perez, D., Reinshagen, K., Geijtenbeek, T. B. H., van Goudoever, J. B. & Bunders, M. J., 1 May 2021, In: Mucosal immunology. 14, 3, p. 605-614 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access5 Citations (Scopus) -
In vitro co-culture of human intestinal organoids and lamina propria-derived CD4+ T cells
Schreurs, R. R. C. E., Baumdick, M. E., Drewniak, A. & Bunders, M. J., 18 Jun 2021, In: STAR Protocols. 2, 2, 100519.Research output: Contribution to journal › Article › Academic › peer-review
Open Access6 Citations (Scopus)