Ger Stienen

Research output

Research output per year 1998 2006 2008 2009 2010 2011 2013 2014 2020

• 104 Article
• 5 Review article
• 1 Chapter
• 1 Erratum/Corrigendum
• 1 More
  • 1 Letter

Research output per year

Research output per year

Search results

• 2020

  Disturbed cardiac mitochondrial and cytosolic calcium handling in a metabolic risk-related rat model of heart failure with preserved ejection fraction

  Miranda-Silva, D., Wüst, R. C. I., Conceição, G., Gonçalves-Rodrigues, P., Gonçalves, N. D., Gonçalves, A., Kuster, D. W. D., Leite-Moreira, A. F., van der Velden, J., de Sousa Beleza, J. M., Magalhães, J., Stienen, G. J. M. & Falcão-Pires, I., 1 Mar 2020, In: Acta Physiologica. 228, 3, p. e13378 e13378.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  46 Citations (Scopus)

• Orthophosphate increases the efficiency of slow muscle-myosin isoform in the presence of omecamtiv mecarbil

  Governali, S., Caremani, M., Gallart, C., Pertici, I., Stienen, G., Piazzesi, G., Ottenheijm, C. A. C., Lombardi, V. & Linari, M., 1 Dec 2020, In: Nature communications. 11, 1, 3405.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  11 Citations (Scopus)
• 2019

  Inotropic interventions do not change the resting state of myosin motors during cardiac diastole

  Caremani, M., Pinzauti, F., Powers, J. D., Governali, S., Narayanan, T., Stienen, G. J. M., Reconditi, M., Linari, M., Lombardi, V. & Piazzesi, G., 1 Jan 2019, In: The Journal of general physiology. 151, 1, p. 53-65 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  26 Citations (Scopus)
• 2018

  A 3D diffusional-compartmental model of the calcium dynamics in cytosol, sarcoplasmic reticulum and mitochondria of murine skeletal muscle fibers

  Marcucci, L., Canato, M., Protasi, F., Stienen, G. J. M. & Reggiani, C., 2018, In: PLOS ONE. 13, 7, e0201050.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  17 Citations (Scopus)

• Dysfunctional sarcomere contractility contributes to muscle weakness in ACTA1-related nemaline myopathy (NEM3)

  Joureau, B., de Winter, J. M., Conijn, S., Bogaards, S. J. P., Kovacevic, I., Kalganov, A., Persson, M., Lindqvist, J., Stienen, G. J. M., Irving, T. C., Ma, W., Yuen, M., Clarke, N. F., Rassier, D. E., Malfatti, E., Romero, N. B., Beggs, A. H. & Ottenheijm, C. A. C., 1 Feb 2018, In: Annals of neurology. 83, 2, p. 269-282 14 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  24 Citations (Scopus)

• The force and stiffness of myosin motors in the isometric twitch of a cardiac trabecula and the effect of the extracellular calcium concentration

  Pinzauti, F., Pertici, I., Reconditi, M., Narayanan, T., Stienen, G. J. M., Piazzesi, G., Lombardi, V., Linari, M. & Caremani, M., 2018, In: Journal of physiology. 596, 13, p. 2581-2596

  Research output: Contribution to journal › Article › Academic › peer-review
  17 Citations (Scopus)
• 2017

  Diaphragm Atrophy and Weakness in the Absence of Mitochondrial Dysfunction in the Critically Ill

  van den Berg, M., Hooijman, P. E., Beishuizen, A., de Waard, M. C., Paul, M. A., Hartemink, K. J., van Hees, H. W. H., Lawlor, M. W., Brocca, L., Bottinelli, R., Pellegrino, M. A., Stienen, G. J. M., Heunks, L. M. A., Wüst, R. C. I. & Ottenheijm, C. A., 15 Dec 2017, In: American journal of respiratory and critical care medicine. 196, 12, p. 1544-1558 15 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  50 Citations (Scopus)

• Empagliflozin decreases myocardial cytoplasmic Na(+) through inhibition of the cardiac Na(+)/H(+) exchanger in rats and rabbits

  Baartscheer, A., Schumacher, C. A., Wüst, R. C. I., Fiolet, J. W. T., Stienen, G. J. M., Coronel, R. & Zuurbier, C. J., 1 Mar 2017, In: Diabetologia. 60, 3, p. 568-573 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  474 Citations (Scopus)
• 2016

  Mutation-Specific Effects on Thin Filament Length in Thin Filament Myopathy

  de Winter, J. M., Joureau, B., Lee, E-J., Kiss, B., Yuen, M., Gupta, V. A., Pappas, C. T., Gregorio, C. C., Stienen, G. J. M., Edvardson, S., Wallgren-Pettersson, C., Lehtokari, V-L., Pelin, K., Malfatti, E., Romero, N. B., van Engelen, B. G., Voermans, N. C., Donkervoort, S., Bonnemann, C. G., Clarke, N. F., & 3 othersBeggs, A. H., Granzier, H. & Ottenheijm, C. A. C., Jun 2016, In: Annals of neurology. 79, 6, p. 959-969

  Research output: Contribution to journal › Article › Academic › peer-review
  50 Citations (Scopus)

• Reduced force of diaphragm muscle fibers in patients with chronic thromboembolic pulmonary hypertension

  Manders, E., Bonta, P. I., Kloek, J. J., Symersky, P., Bogaard, H-J., Hooijman, P. E., Jasper, J. R., Malik, F. I., Stienen, G. J. M., Vonk-Noordegraaf, A., de Man, F. S. & Ottenheijm, C. A. C., 1 Jul 2016, In: American journal of physiology. Lung cellular and molecular physiology. 311, 1, p. L20-L28

  Research output: Contribution to journal › Article › Academic › peer-review
  24 Citations (Scopus)

• Size and speed of the working stroke of cardiac myosin in situ

  Caremani, M., Pinzauti, F., Reconditi, M., Piazzesi, G., Stienen, G. J. M., Lombardi, V. & Linari, M., 29 Mar 2016, In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 113, 13, p. 3675-3680

  Research output: Contribution to journal › Article › Academic › peer-review
  37 Citations (Scopus)
• 2015

  A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis

  Wijnker, P. J. M., Li, Y., Zhang, P., Foster, D. B., dos Remedios, C., van Eyk, J. E., Stienen, G. J. M., Murphy, A. M. & van der Velden, J., 2015, In: Journal of molecular and cellular cardiology. 82, p. 93-103

  Research output: Contribution to journal › Article › Academic › peer-review
  19 Citations (Scopus)

• Effect of levosimendan on the contractility of muscle fibers from nemaline myopathy patients with mutations in the nebulin gene

  de Winter, J. M., Joureau, B., Sequeira Oliveira, V., Clarke, N. F., van der Velden, J., Stienen, G. J. M., Granzier, H., Beggs, A. H. & Ottenheijm, C. A. C., 2015, In: Skeletal Muscle. 5, 12.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  23 Citations (Scopus)

• Quadriceps muscle fibre dysfunction in patients with pulmonary arterial hypertension

  Manders, E., Ruiter, G., Bogaard, H. J., Stienen, G. J. M., Vonk Noordegraaf, A., de Man, F. S. & Ottenheijm, C. A. C., 2015, In: European respiratory journal. 45, 6, p. 1737-1740

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  18 Citations (Scopus)
• 2014

  Altered myocardial force generation in end-stage human heart failure

  Papp, Z., van der Velden, J., Borbely, A., Edes, I. & Stienen, G. J. M., 2014, In: ESC heart failure. 1, 2, p. 160-165

  Research output: Contribution to journal › Article › Academic › peer-review
  6 Citations (Scopus)

• Contractile dysfunction of left ventricular cardiomyocytes in patients with pulmonary arterial hypertension

  Manders, E., Bogaard, H. J., Handoko, M. L., van de Veerdonk, M. C., Keogh, A., Westerhof, N., Stienen, G. J. M., Dos Remedios, C. G., Humbert, M., Dorfmüller, P., Fadel, E., Guignabert, C., Van Der Velden, J., Vonk-Noordegraaf, A., De Man, F. S. & Ottenheijm, C. A. C., 8 Jul 2014, In: Journal of the American College of Cardiology. 64, 1, p. 28-37 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  78 Citations (Scopus)

• Faster cross-bridge detachment and increased tension cost in human hypertrophic cardiomyopathy with the R403Q MYH7 mutation

  Witjas-Paalberends, E. R., Ferrara, C., Scellini, B., Piroddi, N., Montag, J., Tesi, C., Stienen, G. J. M., Michels, M., Ho, C. Y., Kraft, T., Poggesi, C. & van der Velden, J., 2014, In: Journal of Physiology - London. 592, 15, p. 3257-3272

  Research output: Contribution to journal › Article › Academic › peer-review
  55 Citations (Scopus)

• Gene-specific increase in the energetic cost of contraction in hypertrophic cardiomyopathy caused by thick filament mutations

  Witjas-Paalberends, E. R., Guclu, A., Germans, T., Knaapen, P., Harms, H. J., Vermeer, A. M. C., Christiaans, I., Wilde, A. A. M., dos Remedios, C., Lammertsma, A. A., van Rossum, A. C., Stienen, G. J. M., van Slegtenhorst, M., Schinkel, A. F., Michels, M., Ho, C. Y., Poggesi, C. & van der Velden, J., 2014, In: Cardiovascular research. 103, 2, p. 248-257

  Research output: Contribution to journal › Article › Academic › peer-review
  84 Citations (Scopus)

• Length-dependent activation is modulated by cardiac troponin I bisphosphorylation at Ser23 and Ser24 but not by Thr143 phosphorylation

  Wijnker, P. J. M., Sequeira Oliveira, V., Foster, D. B., Li, Y. J., dos Remedios, C. G., Murphy, A. M., Stienen, G. J. M. & van der Velden, J., 2014, In: American journal of physiology. Heart and circulatory physiology. 306, 8, p. H1171-H1181

  Research output: Contribution to journal › Article › Academic › peer-review
  42 Citations (Scopus)

• Phosphorylation of protein kinase C sites Ser42/44 decreases Ca2+-sensitivity and blunts enhanced length-dependent activation in response to protein kinase A in human cardiomyocytes

  Wijnker, P. J. M., Sequeira Oliveira, V., Witjas-Paalberends, E. R., Foster, D. B., dos Remedios, C. G., Murphy, A. M., Stienen, G. J. M. & van der Velden, J., 2014, In: Archives of Biochemistry and Biophysics. 554, p. 11-21

  Research output: Contribution to journal › Article › Academic › peer-review
  15 Citations (Scopus)

• Preserved cross-bridge kinetics in human hypertrophic cardiomyopathy patients with MYBPC3 mutations

  van Dijk, S. J., Boontje, N. M., Heymans, M. W., ten Cate, F. J., Michels, M., dos Remedios, C., Dooijes, D., van Slegtenhorst, M. A., van der Velden, J. & Stienen, G. J. M., 2014, In: Pflügers Archiv European Journal of Physiology. 466, 8, p. 1619-1633

  Research output: Contribution to journal › Article › Academic › peer-review
  11 Citations (Scopus)

• Protein Changes Contributing to Right Ventricular Cardiomyocyte Diastolic Dysfunction in Pulmonary Arterial Hypertension

  Rain, S., da Silva Goncalves Bos, D., Handoko, M. L., Westerhof, N., Stienen, G. J. M., Ottenheijm, C. A. C., Goebel, M., Dorfmuller, P., Guignabert, C., Humbert, M., Bogaard, H. J., dos Remedios, C., Saripalli, C., Hidalgo, C. G., Granzier, H. L., Vonk-Noordegraaf, A., van der Velden, J. & de Man, F. S., 2014, In: Journal of American Heart Association. 3, 3, e000716.

  Research output: Contribution to journal › Article › Academic › peer-review
  59 Citations (Scopus)

• Troponin I phosphorylation in human myocardium in health and disease

  Wijnker, P. J. M., Murphy, A. M., Stienen, G. J. M. & van der Velden, J., 2014, In: Netherlands heart journal. 22, 10, p. 463-469

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  26 Citations (Scopus)

• Unaffected contractility of diaphragm muscle fibers in humans on mechanical ventilation

  Hooijman, P. E., Paul, M. A., Stienen, G. J. M., Beishuizen, A., van Hees, H. W. H., Singhal, S., Bashir, M., Budak, M. T., Morgen, J., Barsotti, R. J., Levine, S. & Ottenheijm, C. A. C., 2014, In: American journal of physiology. Lung cellular and molecular physiology. 307, 6, p. L460-L470

  Research output: Contribution to journal › Article › Academic › peer-review
  10 Citations (Scopus)
• 2013

  Deleting exon 55 from the nebulin gene induces severe muscle weakness in a mouse model for nemaline myopathy

  Ottenheijm, C. A. C., Buck, D., de Winter, J. M., Ferrara, C., Piroddi, N., Tesi, C., Jasper, J. R., Malik, F. I., Meng, H., Stienen, G. J. M., Beggs, A. H., Labeit, S., Poggesi, C., Lawlor, M. W. & Granzier, H., 2013, In: Brain. 136, p. 1718-1731

  Research output: Contribution to journal › Article › Academic › peer-review
  53 Citations (Scopus)

• Determining the role of sarcomeric proteins in facioscapulohumeral muscular dystrophy: a study protocol

  Lassche, S., Ottenheijm, C. A. C., Voermans, N. C., Westeneng, H. J., Janssen, B. H., van der Maarel, S. M., Hopman, M. T., Padberg, G. W., Stienen, G. J. M. & van Engelen, B. G. M., 2013, In: BMC Neurology. 13, 144.

  Research output: Contribution to journal › Article › Academic › peer-review
  11 Citations (Scopus)

• ENerGetIcs in hypertrophic cardiomyopathy: traNslation between MRI, PET and cardiac myofilament function (ENGINE study)

  Guclu, A., Germans, T., Witjas-Paalberends, E. R., Stienen, G. J. M., Brouwer, W., Harms, H., Marcus, J. T., Vonk, A. B. A., Stooker, W., Yilmaz, A., Klein, P., ten Berg, J. M., Kluin, J., Asselbergs, F., Lammertsma, A. A., Knaapen, P., van Rossum, A. C. & van der Velden, J., 2013, In: Netherlands heart journal. 21, 12, p. 567-571

  Research output: Contribution to journal › Article › Academic › peer-review
  15 Citations (Scopus)

• Familial hypertrophic cardiomyopathy: Functional effects of myosin mutation R723G in cardiomyocytes

  Kraft, T., Witjas-Paalberends, E. R., Boontje, N., Tripathi, S., Brandis, A., Montag, J., Hodgkinson, J. L., Francino, A., Navarro-Lopez, F., Brenner, B., Stienen, G. J. M. & van der Velden, J., 2013, In: Journal of molecular and cellular cardiology. 57, p. 13-22

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  48 Citations (Scopus)

• Impact of site-specific phosphorylation of protein kinase A sites Ser(23) and Ser(24) of cardiac troponin I in human cardiomyocytes

  Wijnker, P. J. M., Foster, D. B., Tsao, A. L., Frazier, A. H., dos Remedios, C. G., Murphy, A. M., Stienen, G. J. M. & van der Velden, J., 2013, In: American journal of physiology. Heart and circulatory physiology. 304, 2, p. H260-H268

  Research output: Contribution to journal › Article › Academic › peer-review
  46 Citations (Scopus)

• In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype

  Gineste, C., de Winter, J. M., Kohl, C., Witt, C. C., Giannesini, B., Brohm, K., Le Fur, Y., Gretz, N., Vilmen, C., Pecchi, E., Jubeau, M., Cozzone, P. J., Stienen, G. J. M., Granzier, H., Labeit, S., Ottenheijm, C. A. C., Bendahan, D. & Gondin, J., 2013, In: Neuromuscular disorders. 23, 4, p. 357-369

  Research output: Contribution to journal › Article › Academic › peer-review
  21 Citations (Scopus)

• Mitochondrial Ca2+-Handling in Fast Skeletal Muscle Fibers from Wild Type and Calsequestrin-Null Mice

  Scorzeto, M., Giacomello, M., Toniolo, L., Canato, M., Blaauw, B., Paolini, C., Protasi, F., Reggiani, C. & Stienen, G. J. M., 2013, In: PLOS ONE. 8, 10, e74919.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  20 Citations (Scopus)

• Mutations in MYH7 reduce the force generating capacity of sarcomeres in human familial hypertrophic cardiomyopathy

  Witjas-Paalberends, E. R., Piroddi, N., Stam, C. J., van Dijk, S. J., Oliviera, V. S., Ferrara, C., Scellini, B., Hazebroek, M., ten Cate, F. J., van Slegtenhorst, M., dos Remedios, C., Niessen, H. W. M., Tesi, C., Stienen, G. J. M., Heymans, S., Michels, M., Poggesi, C. & van der Velden, J., 2013, In: Cardiovascular research. 99, 3, p. 432-441

  Research output: Contribution to journal › Article › Academic › peer-review
  76 Citations (Scopus)

• Perturbed Length-Dependent Activation in Human Hypertrophic Cardiomyopathy With Missense Sarcomeric Gene Mutations

  Sequeira Oliveira, V., Wijnker, P. J. M., Nijenkamp, L. L. A. M., Kuster, D. W. D., Najafi, A., Witjas-Paalberends, E. R., Regan, J. A., Boontje, N., ten Cate, F. J., Germans, T., Carrier, L., Sadayappan, S., van Slegtenhorst, M. A., Zaremba, R., Foster, D. B., Murphy, A. M., Poggesi, C., dos Remedios, C., Stienen, G. J. M., Ho, C. Y., & 2 othersMichels, M. & van der Velden, J., 2013, In: Circulation Research. 112, 11, p. 1491-1505

  Research output: Contribution to journal › Article › Academic › peer-review
  160 Citations (Scopus)

• PKC alpha-Specific Phosphorylation of the Troponin Complex in Human Myocardium: A Functional and Proteomics Analysis

  Kooij, V., Zhang, P. B., Piersma, S. R., Sequeira Oliveira, V., Boontje, N., Wijnker, P. J. M., Jimenez, C. R., Jaquet, K. E., dos Remedios, C., Murphy, A. M., van Eyk, J. E., van der Velden, J. & Stienen, G. J. M., 2013, In: PLOS ONE. 8, 10, 10 p., e74847.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  29 Citations (Scopus)

• Right ventricular diastolic impairment in patients with pulmonary arterial hypertension

  Rain, S., Handoko, M. L., Trip, P., Gan, C. T., Westerhof, N., Stienen, G. J. M., Paulus, W. J., Ottenheijm, C. A. C., Marcus, J. T., Dorfmuller, P., Guignabert, C., Humbert, M., Macdonald, P., dos Remedios, C., Postmus, P. E., Saripalli, C., Hidalgo, C. G., Granzier, H. L., Vonk-Noordegraaf, A., van der Velden, J., & 1 othersde Man, F. S., 2013, In: Circulation. 128, 18, p. 2016-2025

  Research output: Contribution to journal › Article › Academic › peer-review
  283 Citations (Scopus)

• Sarcomeric dysfunction contributes to muscle weakness in facioscapulohumeral muscular dystrophy

  Lassche, S., Stienen, G. J. M., Irving, T. C., van der Maarel, S. M., Voermans, N. C., Padberg, G. W., Granzier, H., van Engelen, B. G. M. & Ottenheijm, C. A. C., 2013, In: Neurology. 80, 8, p. 733-737

  Research output: Contribution to journal › Article › Academic › peer-review
  34 Citations (Scopus)

• Troponin activator augments muscle force in nemaline myopathy patients with nebulin mutations

  de Winter, J. M., Buck, D., Hidalgo, C., Jasper, J. R., Malik, F. I., Clarke, N. F., Stienen, G. J. M., Lawlor, M. W., Beggs, A. H., Ottenheijm, C. A. C. & Granzier, H., 2013, In: Journal of medical genetics. 50, 6, p. 383-392

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  43 Citations (Scopus)
• 2012

  A Large Human Centrifuge for Exploration and Exploitation Research

  van Loon, J. J. W. A., Baeyens, J. P., Berte, J., Blanc, S., Braak, L., Bok, K., Bos, J. E., Boyle, R., Bravenboer, N., Eekhoff, E. M. W., Chouker, A., Clement, G., Cras, P., Cross, E., Custaud, M. A., de Angelis, M., Delavaux, T., Delfos, R., Poelma, C., Denise, P., & 38 othersFelsenberg, D., Fong, K., Fuller, C., Grillner, S., Groen, E., Harlaar, J., Heer, M., Heglund, N., Hinghofer-Szalkay, H., Goswami, N., Hughes-Fulford, M., Iwase, S., Karemaker, J. M., Langdahl, B. L., Linnarsson, D., Lüthen, C., Monici, M., Mulder, E., Narici, M. V., Norsk, P., Paloski, W., Prisk, K., Rutten, M., Singer, P., Stegeman, D. F., Stephan, A., Stienen, G. J. M., Suedfeld, P., Tesch, P., Ullrich, O., van den Berg, R., van de Heyning, P., Delahaye, A., Veyt, J., Vico, L., Woodward, E., Young, L. & Wuyts, F. L., 2012, In: Annales Kinesiologiae. 3, 1, p. 107-121

  Research output: Contribution to journal › Article › Academic

• Contractile Dysfunction Irrespective of the Mutant Protein in Human Hypertrophic Cardiomyopathy With Normal Systolic Function

  van Dijk, S. J., Paalberends, E. R., Najafi, A., Michels, M., Sadayappan, S., Carrier, L., Boontje, N. M., Kuster, D. W. D., van Slegtenhorst, M., Dooijes, D., dos Remedios, C., ten Cate, F. J., Stienen, G. J. M. & van der Velden, J., 2012, In: Circulation. Heart failure. 5, 1, p. 36-U126

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  108 Citations (Scopus)

• Diaphragm weakness in pulmonary arterial hypertension: role of sarcomeric dysfunction

  Manders, E., de Man, F. S., Handoko, M. L., Westerhof, N., van Hees, H. W. H., Stienen, G. J. M., Vonk Noordegraaf, A. & Ottenheijm, C. A. C., 2012, In: American journal of physiology. Lung cellular and molecular physiology. 303, 12, p. L1070-L1078

  Research output: Contribution to journal › Article › Academic › peer-review
  20 Citations (Scopus)

• Low myocardial protein kinase G activity in heart failure with preserved ejection fraction

  van Heerebeek, L., Hamdani, N., Falcao-Pires, I., Leite-Moreira, A. F., Begieneman, M. P. V., Bronzwaer, J. G. F., van der Velden, J., Stienen, G. J. M., Laarman, G. J., Somsen, A. T., Verheugt, F. W. A., Niessen, H. W. M. & Paulus, W. J., 14 Aug 2012, In: Circulation. 126, 7, p. 830-839 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  395 Citations (Scopus)

• Titin-based stiffening of muscle fibers in Ehlers-Danlos Syndrome

  Ottenheijm, C. A. C., Voermans, N. C., Hudson, B. D., Irving, T., Stienen, G. J. M., van Engelen, B. G. & Granzier, H., 2012, In: Journal of Applied Physiology. 112, 7, p. 1157-1165

  Research output: Contribution to journal › Article › Academic › peer-review
  27 Citations (Scopus)

• Training one type of striated muscle to counteract failure of another type

  Stienen, G. J. M. & Ottenheijm, C. A. C., 2012, In: Journal of Physiology - London. 590, 6, p. 1307-1307

  Research output: Contribution to journal › Article › Academic › peer-review
• 2011

  Changes in cross-bridge cycling underlie muscle weakness in patients with tropomyosin 3-based myopathy

  Ottenheijm, C. A. C., Lawlor, M. W., Stienen, G. J. M., Granzier, H. & Beggs, A. H., 2011, In: Human Molecular Genetics. 20, 10, p. 2015-2025

  Research output: Contribution to journal › Article › Academic › peer-review
  56 Citations (Scopus)

• Diabetes mellitus worsens diastolic left ventricular dysfunction in aortic stenosis through altered myocardial structure and cardiomyocyte stiffness

  Falcão-Pires, I., Hamdani, N., Borbely, A., Gavina, C., Schalkwijk, C. G., van der Velden, J., van Heerebeek, L., Stienen, G. J. M., Niessen, H. W. M., Leite-Moreira, A. F. & Paulus, W. J., 6 Sept 2011, In: Circulation. 124, 10, p. 1151-1159 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  168 Citations (Scopus)

• Diaphragm muscle fiber function and structure in humans with hemidiaphragm paralysis

  Welvaart, W. N., Paul, M. A., van Hees, H. W. H., Stienen, G. J. M., Niessen, H. W. M., de Man, F. S., Sieck, G. C., Vonk Noordegraaf, A. & Ottenheijm, C. A. C., 2011, In: American journal of physiology. Lung cellular and molecular physiology. 301, 2, p. L228-L235

  Research output: Contribution to journal › Article › Academic › peer-review
  18 Citations (Scopus)

• Diaphragm Muscle Fiber Weakness in Pulmonary Hypertension

  de Man, F. S., van Hees, H. W. H., Handoko, M. L., Niessen, H. W. M., Schalij, I., Humbert, M., Dorfmuller, P., Mercier, O., Bogaard, H. J., Postmus, P. E., Westerhof, N., Stienen, G. J. M., van der Laarse, W. J., Vonk Noordegraaf, A. & Ottenheijm, C. A. C., 2011, In: American journal of respiratory and critical care medicine. 183, 10, p. 1411-1418

  Research output: Contribution to journal › Article › Academic › peer-review
  66 Citations (Scopus)

• Enhanced myofilament responsiveness upon β-adrenergic stimulation in post-infarct remodeled myocardium.

  Boontje, N., Merkus, D., Zaremba, R., Versteilen, A. M. G., de Waard, M., Mearini, G., de Beer, V. J., Carrier, L., Walker, L. A., Niessen, H. W. M., Dobrev, D., Stienen, G. J. M., Duncker, D. J. & van der Velden, J., 2011, In: Journal of molecular and cellular cardiology. 50, p. 487-499

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  22 Citations (Scopus)

• Protein phosphatase 2A affects myofilament contractility in non-failing but not in failing human myocardium

  Wijnker, P. J. M., Boknik, P., Gergs, U., Muller, F. U., Neumann, J., dos Remedios, C., Schmitz, W., Sindermann, J. R., Stienen, G. J. M., van der Velden, J. & Kirchhefer, U., 2011, In: Journal of muscle research and cell motility. 32, 3, p. 221-233

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  46 Citations (Scopus)

• Selective diaphragm muscle weakness following contractile inactivity during thoracic surgery

  Welvaart, W. N., Paul, M. A., Stienen, G. J. M., van Hees, H. W. H., Loer, S. A., Bouwman, R. A., Niessen, H. W. M., de Man, F. S., Witt, C. C., Granzier, H., Vonk Noordegraaf, A. & Ottenheijm, C. A. C., 2011, In: Annals of surgery. 254, 6, p. 1044-1049

  Research output: Contribution to journal › Article › Academic › peer-review
  43 Citations (Scopus)