Tytgat Institute for Liver and Intestinal Research

Search results

  • 2021

    Does oncological outcome differ between restorative and nonrestorative low anterior resection in patients with primary rectal cancer?

    the Dutch Snapshot Research Group, Apr 2021, In: Colorectal disease. 23, 4, p. 843-852 10 p.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    5 Citations (Scopus)

  • Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis

    Reich, M., Spomer, L., Klindt, C., Fuchs, K., Stindt, J., Deutschmann, K., Höhne, J., Liaskou, E., Hov, J. R., Karlsen, T. H., Beuers, U., Verheij, J., Ferreira-Gonzalez, S., Hirschfield, G., Forbes, S. J., Schramm, C., Esposito, I., Nierhoff, D., Fickert, P., Fuchs, C. D., & 13 othersTrauner, M., García-Beccaria, M., Gabernet, G., Nahnsen, S., Mallm, J-P., Vogel, M., Schoonjans, K., Lautwein, T., Köhrer, K., Häussinger, D., Luedde, T., Heikenwalder, M. & Keitel, V., 1 Sept 2021, In: Journal of Hepatology. 75, 3, p. 634-646 13 p.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    45 Citations (Scopus)

  • Early Life Antibiotics Influence In Vivo and In Vitro Mouse Intestinal Epithelium Maturation and Functioning

    Martins Garcia, T., van Roest, M., Vermeulen, J. L. M., Meisner, S., Smit, W. L., Silva, J., Koelink, P. J., Koster, J., Faller, W. J., Wildenberg, M. E., van Elburg, R. M., Muncan, V. & Renes, I. B., 1 Jan 2021, In: Cellular and Molecular Gastroenterology and Hepatology. 12, 3, p. 943-981 39 p.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    14 Citations (Scopus)

  • EASL recognition award recipient 2021: Prof. Dieter Häussinger

    Beuers, U., 1 Jul 2021, In: Journal of Hepatology. 75, 1, p. 7-9 3 p.

    Research output: Contribution to journal › Editorial › Professional

    Open Access

  • Effects of fecal microbiota transplant on DNA methylation in subjects with metabolic syndrome

    van der Vossen, E. W. J., Bastos, D., Stols-Gonçalves, D., de Goffau, M. C., Davids, M., Pereira, J. P. B., Li Yim, A. Y. F., Henneman, P., Netea, M. G., de Vos, W. M., de Jonge, W., Groen, A. K., Nieuwdorp, M. & Levin, E., 2021, In: Gut Microbes. 13, 1, 1993513.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    27 Citations (Scopus)

  • Efficacy of AAV8-hUGT1A1 with Rapamycin in neonatal, suckling, and juvenile rats to model treatment in pediatric CNs patients

    Shi, X., Aronson, S. J., ten Bloemendaal, L., Duijst, S., Bakker, R. S., de Waart, D. R., Bortolussi, G., Collaud, F., Oude Elferink, R. P., Muro, A. F., Mingozzi, F., Ronzitti, G. & Bosma, P. J., 12 Mar 2021, In: Molecular therapy. Methods & clinical development. 20, p. 287-297 11 p.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    9 Citations (Scopus)

  • Endoplasmic reticulum stress regulates the intestinal stem cell state through CtBP2

    Meijer, B. J., Smit, W. L., Koelink, P. J., Westendorp, B. F., de Boer, R. J., van der Meer, J. H. M., Vermeulen, J. L. M., Paton, J. C., Paton, A. W., Qin, J., Dekker, E., Muncan, V., van den Brink, G. R. & Heijmans, J., 1 Dec 2021, In: Scientific reports. 11, 1, 9892.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    8 Citations (Scopus)

  • Endpoints and design of clinical trials in patients with decompensated cirrhosis: Position paper of the LiverHope Consortium

    Solà, E., Pose, E., Campion, D., Piano, S., Roux, O., Simon-Talero, M., Uschner, F., de Wit, K., Zaccherini, G., Alessandria, C., Beuers, U., Caraceni, P., Francoz, C., Mookerjee, R. P., Trebicka, J., Vargas, V., Serra, M., Torres, F., Montagnese, S., Krag, A., & 6 othersHernaez, R., Korenjak, M., Watson, H., Abraldes, J. G., Kamath, P. S. & Ginès, P., Jan 2021, In: Journal of Hepatology. 74, 1, p. 200-219 20 p.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    17 Citations (Scopus)

  • Epithelial argininosuccinate synthetase is dispensable for intestinal regeneration and tumorigenesis

    van der Meer, J. H. M., de Boer, R. J., Meijer, B. J., Smit, W. L., Vermeulen, J. L. M., Meisner, S., van Roest, M., Koelink, P. J., Dekker, E., Hakvoort, T. B. M., Koster, J., Hawinkels, L. J. A. C., Heijmans, J., Struijs, E. A., Boermeester, M. A., van den Brink, G. R. & Muncan, V., 1 Oct 2021, In: Cell Death & Disease. 12, 10, 897.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    4 Citations (Scopus)

  • Epithelium-derived Indian Hedgehog restricts stromal expression of ErbB family members that drive colonic tumor cell proliferation

    Westendorp, F., Karpus, O. N., Koelink, P. J., Vermeulen, J. L. M., Meisner, S., Koster, J., Büller, N. V. J. A., Wildenberg, M. E., Muncan, V. & van den Brink, G. R., 4 Mar 2021, In: Oncogene. 40, 9, p. 1628-1643 16 p.

    Research output: Contribution to journal › Article › Academic › peer-review

    5 Citations (Scopus)

  • Erratum to: “Hepatobiliary acid-base homeostasis: Insights from analogous secretory epithelia” (J Hepatol 2021; 74: 428-441) (Journal of Hepatology (2021) 74(2) (428–441), (S0168827820336904), (10.1016/j.jhep.2020.10.010))

    Trampert, D. C., van de Graaf, S. F. J., Jongejan, A., Oude Elferink, R. P. J. & Beuers, U., Aug 2021, In: Journal of Hepatology. 75, 2, p. 497 1 p.

    Research output: Contribution to journal › Comment/Letter to the editor › Academic

  • Evidence for glutamine synthetase function in mouse spinal cord oligodendrocytes

    Ben Haim, L., Schirmer, L., Zulji, A., Sabeur, K., Tiret, B., Ribon, M., Chang, S., Lamers, W. H., Boillée, S. V., Chaumeil, M. M. & Rowitch, D. H., Dec 2021, In: GLIA. 69, 12, p. 2812-2827 16 p.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    12 Citations (Scopus)

  • Expression of MAdCAM-1 and Gut-homing T Cells in Inflamed Pouch Mucosa

    de Krijger, M., Wildenberg, M. E., Mookhoek, A., Verheul, S., de Jonge, W. J. & Ponsioen, C. Y., 1 Sept 2021, In: Journal of Crohn's and Colitis. 15, 9, p. 1491-1499 9 p.

    Research output: Contribution to journal › Article › Academic › peer-review

    5 Citations (Scopus)

  • Feeding the Gut–Liver Axis in PSC: What Makes It Different from IBD?

    Ponsioen, C. Y. & de Jonge, W. J., Sept 2021, In: Gastroenterology. 161, 3, p. 1070-1071 2 p.

    Research output: Contribution to journal › Comment/Letter to the editor › Academic

    Open Access

  • Fibrates for Itch (FITCH) in Fibrosing Cholangiopathies: A Double-Blind, Randomized, Placebo-Controlled Trial

    Netherlands Association for the Study of the Liver-Cholestasis Working Group, Feb 2021, In: Gastroenterology. 160, 3, p. 734-743.e6

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    92 Citations (Scopus)

  • Gene therapy for inherited jaundice

    Aronson, S. J., 2021, 230 p.

    Research output: PhD Thesis › Phd-Thesis - Research and graduation internal

    Open Access

  • Gene therapy for progressive familial intrahepatic cholestasis: Current progress and future prospects

    Bosma, P. J., Wits, M. & Oude-Elferink, R. P. J., 1 Jan 2021, In: International journal of molecular sciences. 22, 1, p. 1-13 13 p., 273.

    Research output: Contribution to journal › Review article › Academic › peer-review

    Open Access
    15 Citations (Scopus)

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

    none, Álvarez, É. M. C., Alves, S., Alves da Costa, C., Alzaharna, M. M., Amadio, M., Amantini, C., Amaral, C., Ambrosio, S., Amer, A. O., Ammanathan, V., An, Z., Andersen, S. U., Andrabi, S. A., Andrade-Silva, M., Andres, A. M., Angelini, S., Ann, D., Anozie, U. C., Ansari, M. Y., & 2,860 othersAntas, P., Antebi, A., Antón, Z., Anwar, T., Apetoh, L., Apostolova, N., Araki, T., Araki, Y., Arasaki, K., Araújo, W. L., Araya, J., Arden, C., Arévalo, M-A., Arguelles, S., Arias, E., Arikkath, J., Arimoto, H., Ariosa, A. R., Armstrong-James, D., Arnauné-Pelloquin, L., Aroca, A., Arroyo, D. S., Arsov, I., Artero, R., Asaro, D. M. L., Aschner, M., Ashrafizadeh, M., Ashur-Fabian, O., Atanasov, A. G., Au, A. K., Auberger, P., Auner, H. W., Aurelian, L., Autelli, R., Avagliano, L., Ávalos, Y., Aveic, S., Aveleira, C. A., Avin-Wittenberg, T., Aydin, Y., Ayton, S., Ayyadevara, S., Azzopardi, M., Baba, M., Backer, J. M., Backues, S. K., Bae, D-H., Bae, O-N., Bae, S. H., Baehrecke, E. H., Baek, A., Baek, S-H., Baek, S. H., Bagetta, G., Bagniewska-Zadworna, A., Bai, H., Bai, J., Bai, X., Bai, Y., Bairagi, N., Baksi, S., Balbi, T., Baldari, C. T., Balduini, W., Ballabio, A., Ballester, M., Balazadeh, S., Balzan, R., Bandopadhyay, R., Banerjee, S., Banerjee, S., Bánréti, Á., Bao, Y., Baptista, M. S., Baracca, A., Barbati, C., Bargiela, A., Barilà, D., Barlow, P. G., Barmada, S. J., Barreiro, E., Barreto, G. E., Bartek, J., Bartel, B., Bartolome, A., Barve, G. R., Basagoudanavar, S. H., Bassham, D. C., Bast, R. C., Basu, A., Batoko, H., Batten, I., Baulieu, E. E., Baumgarner, B. L., Bayry, J., Beale, R., Beau, I., Beaumatin, F., Bechara, L. R. G., Beck, G. R., Beers, M. F., Begun, J., Behrends, C., Behrens, G. M. N., Bei, R., Bejarano, E., Bel, S., Behl, C., Belaid, A., Belgareh-Touzé, N., Bellarosa, C., Belleudi, F., Belló Pérez, M., Bello-Morales, R., Beltran, J. S. D. O., Beltran, S., Benbrook, D. M., Bendorius, M., Benitez, B. A., Benito-Cuesta, I., Bensalem, J., Berchtold, M. W., Berezowska, S., Bergamaschi, D., Bergami, M., Bergmann, A., Berliocchi, L., Berlioz-Torrent, C., Bernard, A., Berthoux, L., Besirli, C. G., Besteiro, S., Betin, V. M., Beyaert, R., Bezbradica, J. S., Bhaskar, K., Bhatia-Kissova, I., Bhattacharya, R., Bhattacharya, S., Bhattacharyya, S., Bhuiyan, M. S., Bhutia, S. K., Bi, L., Bi, X., Biden, T. J., Bijian, K., Billes, V. A., Binart, N., Bincoletto, C., Birgisdottir, A. B., Bjorkoy, G., Blanco, G., Blas-Garcia, A., Blasiak, J., Blomgran, R., Blomgren, K., Blum, J. S., Boada-Romero, E., Boban, M., Boesze-Battaglia, K., Boeuf, P., Boland, B., Bomont, P., Bonaldo, P., Bonam, S. R., Bonfili, L., Bonifacino, J. S., Boone, B. A., Bootman, M. D., Bordi, M., Borner, C., Bornhauser, B. C., Borthakur, G., Bosch, J., Bose, S., Botana, L. M., Botas, J., Boulanger, C. M., Boulton, M. E., Bourdenx, M., Bourgeois, B., Bourke, N. M., Bousquet, G., Boya, P., Bozhkov, P. V., Bozi, L. H. M., Bozkurt, T. O., Brackney, D. E., Brandts, C. H., Braun, R. J., Braus, G. H., Bravo-Sagua, R., Bravo-San Pedro, J. M., Brest, P., Bringer, M-A., Briones-Herrera, A., Broaddus, V. C., Brodersen, P., Brodsky, J. L., Brody, S. L., Bronson, P. G., Bronstein, J. M., Brown, C. N., Brown, R. E., Brum, P. C., Brumell, J. H., Brunetti-Pierri, N., Bruno, D., Bryson-Richardson, R. J., Bucci, C., Buchrieser, C., Bueno, M., Buitrago-Molina, L. E., Buraschi, S., Buch, S., Buchan, J. R., Buckingham, E. M., Budak, H., Budini, M., Bultynck, G., Burada, F., Burgoyne, J. R., Burón, M. I., Bustos, V., Büttner, S., Butturini, E., Byrd, A., Cabas, I., Cabrera-Benitez, S., Cadwell, K., Cai, J., Cai, L., Cai, Q., Cairó, M., Calbet, J. A., Caldwell, G. A., Caldwell, K. A., Call, J. A., Calvani, R., Calvo, A. C., Calvo-Rubio Barrera, M., Camara, N. O. S., Camonis, J. H., Camougrand, N., Campanella, M., Campbell, E. M., Campbell-Valois, F-X., Campello, S., Campesi, I., Campos, J. C., Camuzard, O., Cancino, J., Candido de Almeida, D., Canesi, L., Caniggia, I., Canonico, B., Cantí, C., Cao, B., Caraglia, M., Caramés, B., Carchman, E. H., Cardenal-Muñoz, E., Cardenas, C., Cardenas, L., Cardoso, S. M., Carew, J. S., Carle, G. F., Carleton, G., Carloni, S., Carmona-Gutierrez, D., Carneiro, L. A., Carnevali, O., Carosi, J. M., Carra, S., Carrier, A., Carrier, L., Carroll, B., Carter, A. B., Carvalho, A. N., Casanova, M., Casas, C., Casas, J., Cassioli, C., Castillo, E. F., Castillo, K., Castillo-Lluva, S., Castoldi, F., Castori, M., Castro, A. F., Castro-Caldas, M., Castro-Hernandez, J., Castro-Obregon, S., Catz, S. D., Cavadas, C., Cavaliere, F., Cavallini, G., Cavinato, M., Cayuela, M. L., Cebollada Rica, P., Cecarini, V., Cecconi, F., Cechowska-Pasko, M., Cenci, S., Ceperuelo-Mallafré, V., Cerqueira, J. J., Cerutti, J. M., Cervia, D., Cetintas, V. B., Cetrullo, S., Chae, H-J., Chagin, A. S., Chai, C-Y., Chakrabarti, G., Chakrabarti, O., Chakraborty, T., Chakraborty, T., Chami, M., Chamilos, G., Chan, D. W., Chan, E. Y. W., Chan, E. D., Chan, H. Y. E., Chan, H. H., Chan, H., Chan, M. T. V., Chan, Y. S., Chandra, P. K., Chang, C-P., Chang, C., Chang, H-C., Chang, K., Chao, J., Chapman, T., Charlet-Berguerand, N., Chatterjee, S., Chaube, S. K., Chaudhary, A., Chauhan, S., Chaum, E., Checler, F., Cheetham, M. E., Chen, C-S., Chen, G-C., Chen, J-F., Chen, L. L., Chen, L., Chen, L., Chen, M., Chen, M-K., Chen, N., Chen, Q., Chen, R-H., Chen, S., Chen, W., Chen, W., Chen, X-M., Chen, X-W., Chen, X., Chen, Y., Chen, Y-G., Chen, Y., Chen, Y., Chen, Y-J., Chen, Y-Q., Chen, Z. S., Chen, Z., Chen, Z-H., Chen, Z. J., Chen, Z., Cheng, H., Cheng, J., Cheng, S-Y., Cheng, W., Cheng, X., Cheng, X-T., Cheng, Y., Cheng, Z., Chen, Z., Cheong, H., Cheong, J. K., Chernyak, B. V., Cherry, S., Cheung, C. F. R., Cheung, C. H. A., Cheung, K-H., Chevet, E., Chi, R. J., Chiang, A. K. S., Chiaradonna, F., Chiarelli, R., Chiariello, M., Chica, N., Chiocca, S., Chiong, M., Chiou, S-H., Chiramel, A. I., Chiurchiù, V., Cho, D-H., Choe, S-K., Choi, A. M. K., Choi, M. E., Choudhury, K. R., Chow, N. S., Chu, C. T., Chua, J. P., Chua, J. J. E., Chung, H., Chung, K. P., Chung, S., Chung, S-H., Chung, Y-L., Cianfanelli, V., Ciechomska, I. A., Cifuentes, M., Cinque, L., Cirak, S., Cirone, M., Clague, M. J., Clarke, R., Clementi, E., Coccia, E. M., Codogno, P., Cohen, E., Cohen, M. M., Colasanti, T., Colasuonno, F., Colbert, R. A., Colell, A., Čolić, M., Coll, N. S., Collins, M. O., Colombo, M. I., Colón-Ramos, D. A., Combaret, L., Comincini, S., Cominetti, M. R., Consiglio, A., Conte, A., Conti, F., Contu, V. R., Cookson, M. R., Coombs, K. M., Coppens, I., Corasaniti, M. T., Corkery, D. P., Cordes, N., Cortese, K., Costa, M. D. C., Costantino, S., Costelli, P., Coto-Montes, A., Crack, P. J., Crespo, J. L., Criollo, A., Crippa, V., Cristofani, R., Csizmadia, T., Cuadrado, A., Cui, B., Cui, J., Cui, Y., Cui, Y., Culetto, E., Cumino, A. C., Cybulsky, A. V., Czaja, M. J., Czuczwar, S. J., D’Adamo, S., D’Amelio, M., D’Arcangelo, D., D’Lugos, A. C., D’Orazi, G., da Silva, J. A., Dafsari, H. S., Dagda, R. K., Dagdas, Y., Daglia, M., Dai, X., Dai, Y., Dai, Y., Dal Col, J., Dalhaimer, P., Dalla Valle, L., Dallenga, T., Dalmasso, G., Damme, M., Dando, I., Dantuma, N. P., Darling, A. L., Das, H., Dasarathy, S., Dasari, S. K., Dash, S., Daumke, O., Dauphinee, A. N., Davies, J. S., Dávila, V. A., Davis, R. J., Davis, T., Dayalan Naidu, S., De Amicis, F., De Bosscher, K., De Felice, F., De Franceschi, L., De Leonibus, C., de Mattos Barbosa, M. G., De Meyer, G. R. Y., De Milito, A., De Nunzio, C., De Palma, C., De Santi, M., De Virgilio, C., De Zio, D., Debnath, J., DeBosch, B. J., Decuypere, J-P., Deehan, M. A., Deflorian, G., DeGregori, J., Dehay, B., Del Rio, G., Delaney, J. R., Delbridge, L. M. D., Delorme-Axford, E., Delpino, M. V., Demarchi, F., Dembitz, V., Demers, N. D., Deng, H., Deng, Z., Dengjel, J., Dent, P., Denton, D., DePamphilis, M. L., Der, C. J., Deretic, V., Descoteaux, A., Devis, L., Devkota, S., Devuyst, O., Dewson, G., Dharmasivam, M., Dhiman, R., di Bernardo, D., Di Cristina, M., Di Domenico, F., Di Fazio, P., Di Fonzo, A., Di Guardo, G., Di Guglielmo, G. M., Di Leo, L., Di Malta, C., Di Nardo, A., Di Rienzo, M., Di Sano, F., Diallinas, G., Diao, J., Diaz-Araya, G., Díaz-Laviada, I., Dickinson, J. M., Diederich, M., Dieudé, M., Dikic, I., Ding, S., Ding, W-X., Dini, L., Dinić, J., Dinic, M., Dinkova-Kostova, A. T., Dionne, M. S., Distler, J. H. W., Diwan, A., Dixon, I. M. C., Djavaheri-Mergny, M., Dobrinski, I., Dobrovinskaya, O., Dobrowolski, R., Dobson, R. C. J., Đokić, J., Dokmeci Emre, S., Donadelli, M., Dong, B., Dong, X., Dong, Z., Dorn II, G. W., Dotsch, V., Dou, H., Dou, J., Dowaidar, M., Dridi, S., Drucker, L., Du, A., Du, C., Du, G., Du, H-N., Du, L-L., du Toit, A., Duan, S-B., Duan, X., Duarte, S. P., Dubrovska, A., Dunlop, E. A., Dupont, N., Durán, R. V., Dwarakanath, B. S., Dyshlovoy, S. A., Ebrahimi-Fakhari, D., Eckhart, L., Edelstein, C. L., Efferth, T., Eftekharpour, E., Eichinger, L., Eid, N., Eisenberg, T., Eissa, N. T., Eissa, S., Ejarque, M., El Andaloussi, A., El-Hage, N., El-Naggar, S., Eleuteri, A. M., El-Shafey, E. S., Elgendy, M., Eliopoulos, A. G., Elizalde, M. M., Elks, P. M., Elsasser, H-P., Elsherbiny, E. S., Emerling, B. M., Emre, N. C. T., Eng, C. H., Engedal, N., Engelbrecht, A-M., Engelsen, A. S. T., Enserink, J. M., Escalante, R., Esclatine, A., Escobar-Henriques, M., Eskelinen, E-L., Espert, L., Eusebio, M-O., Fabrias, G., Fabrizi, C., Facchiano, A., Facchiano, F., Fadeel, B., Fader, C., Faesen, A. C., Fairlie, W. D., Falcó, A., Falkenburger, B. H., Fan, D., Fan, J., Fan, Y., Fang, E. F., Fang, Y., Fang, Y., Fanto, M., Farfel-Becker, T., Faure, M., Fazeli, G., Fedele, A. O., Feldman, A. M., Feng, D., Feng, J., Feng, L., Feng, Y., Feng, Y., Feng, W., Fenz Araujo, T., Ferguson, T. A., Fernández, Á. F., Fernandez-Checa, J. C., Fernández-Veledo, S., Fernie, A. R., Ferrante, A. W., Ferraresi, A., Ferrari, M. F., Ferreira, J. C. B., Ferro-Novick, S., Figueras, A., Filadi, R., Filigheddu, N., Filippi-Chiela, E., Filomeni, G., Fimia, G. M., Fineschi, V., Finetti, F., Finkbeiner, S., Fisher, E. A., Fisher, P. B., Flamigni, F., Fliesler, S. J., Flo, T. H., Florance, I., Florey, O., Florio, T., Fodor, E., Follo, C., Fon, E. A., Forlino, A., Fornai, F., Fortini, P., Fracassi, A., Fraldi, A., Franco, B., Franco, R., Franconi, F., Frankel, L. B., Friedman, S. L., Fröhlich, L. F., Frühbeck, G., Fuentes, J. M., Fujiki, Y., Fujita, N., Fujiwara, Y., Fukuda, M., Fulda, S., Furic, L., Furuya, N., Fusco, C., Gack, M. U., Gaffke, L., Galadari, S., Galasso, A., Galindo, M. F., Gallolu Kankanamalage, S., Galluzzi, L., Galy, V., Gammoh, N., Gan, B., Ganley, I. G., Gao, F., Gao, H., Gao, M., Gao, P., Gao, S-J., Gao, W., Gao, X., Garcera, A., Garcia, M. N., Garcia, V. E., García-Del Portillo, F., Garcia-Escudero, V., Garcia-Garcia, A., Garcia-Macia, M., García-Moreno, D., Garcia-Ruiz, C., García-Sanz, P., Garg, A. D., Gargini, R., Garofalo, T., Garry, R. F., Gassen, N. C., Gatica, D., Ge, L., Ge, W., Geiss-Friedlander, R., Gelfi, C., Genschik, P., Gentle, I. E., Gerbino, V., Gerhardt, C., Germain, K., Germain, M., Gewirtz, D. A., Ghasemipour Afshar, E., Ghavami, S., Ghigo, A., Ghosh, M., Giamas, G., Giampietri, C., Giatromanolaki, A., Gibson, G. E., Gibson, S. B., Ginet, V., Giniger, E., Giorgi, C., Girao, H., Girardin, S. E., Giridharan, M., Giuliano, S., Giulivi, C., Giuriato, S., Giustiniani, J., Gluschko, A., Goder, V., Goginashvili, A., Golab, J., Goldstone, D. C., Golebiewska, A., Gomes, L. R., Gomez, R., Gómez-Sánchez, R., Gomez-Puerto, M. 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    Research output: Contribution to journal › Review article › Academic › peer-review

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    1346 Citations (Scopus)

  • Hepatobiliary acid-base homeostasis: Insights from analogous secretory epithelia

    Trampert, D. C., van de Graaf, S. F. J., Jongejan, A., Oude Elferink, R. P. J. & Beuers, U., Feb 2021, In: Journal of Hepatology. 74, 2, p. 428-441 14 p.

    Research output: Contribution to journal › Review article › Academic › peer-review

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    12 Citations (Scopus)

  • High-Dose Vitamin D Does Not Prevent Postoperative Recurrence of Crohn's Disease in a Randomized Placebo-Controlled Trial

    Dutch-Belgian The Effect of Vitamin D3 to Prevent Postoperative Relapse of Crohn's Disease: A Placebo-controlled Randomized Trial Study Group, 1 Aug 2021, In: Clinical Gastroenterology and Hepatology. 19, 8, p. 1573-1582.e5

    Research output: Contribution to journal › Article › Academic › peer-review

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    20 Citations (Scopus)

  • High prevalence of ulcerative appendicitis in patients with ulcerative colitis

    Heuthorst, L., Mookhoek, A., Wildenberg, M. E., D'Haens, G. R., Bemelman, W. A. & Buskens, C. J., Dec 2021, In: United European gastroenterology journal. 9, 10, p. 1148-1156 9 p.

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    8 Citations (Scopus)

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    Luque-Martin, R., Angell, D. C., Kalxdorf, M., Bernard, S., Thompson, W., Eberl, H. C., Ashby, C., Freudenberg, J., Sharp, C., van den Bossche, J., de Jonge, W. J., Rioja, I., Prinjha, R. K., Neele, A. E., de Winther, M. P. J. & Mander, P. K., 15 Jul 2021, In: Journal of immunology (Baltimore, Md.. 207, 2, p. 555-568 14 p.

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    16 Citations (Scopus)

  • IgG4-related disease of the biliary tract and pancreas: Catching a great mimicker

    Hubers, L. M., 2021, 163 p.

    Research output: PhD Thesis › Phd-Thesis - Research and graduation internal

    Open Access

  • IgG4-related diseases of the digestive tract

    Löhr, J. -M., Vujasinovic, M., Rosendahl, J., Stone, J. H. & Beuers, U., 2021, (E-pub ahead of print) In: Nature Reviews Gastroenterology and Hepatology.

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    44 Citations (Scopus)

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    Bloemendaal, F. M., Peters, C. P., te Velde, A. A., Ponsioen, C. I. J., van den Brink, G. R., Wildenberg, M. E. & Koelink, P. J., 28 Jan 2021, In: Journal of Clinical & Cellular Immunology. 3, 2, p. 91-96

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  • Incisional hernia after abdominal surgery in infants: A retrospective analysis of incidence and risk factors

    Eeftinck Schattenkerk, L. D., Musters, G. D., Coultre, S. E. L., de Jonge, W. J., van Heurn, L. W. E. & Derikx, J. P. M., Nov 2021, In: Journal of Pediatric Surgery. 56, 11, p. 2107-2112 6 p.

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    6 Citations (Scopus)

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    Anderson, R. H., Hikspoors, J. P. J. M., Tretter, J. T., Macías, Y., Spicer, D. E., Lamers, W. H., Sánchez-Quintana, D. & Sternick, E. B., 2021, In: Arrhythmia & electrophysiology review. 10, 4, p. 262-272

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    3 Citations (Scopus)

  • Inhibition of autotaxin by bile salts and bile salt-like molecules increases its expression by feedback regulation

    Langedijk, J. A. G. M., Tolenaars, D., Bolier, R., Lee, Y-T., Meurs, A., Williamson, C., Adorini, L., van de Graaf, S. F. J., Beuers, U. & Elferink, R. O., 1 Nov 2021, In: Biochimica et Biophysica Acta-Molecular Basis of Disease. 1867, 11, 166239.

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    4 Citations (Scopus)

  • Insufficient evidence for NTCP activity in stellate cells

    Kunst, R. F., Paulusma, C. C. & van de Graaf, S. F. J., 15 Dec 2021, (E-pub ahead of print) In: Gut.

    Research output: Contribution to journal › Article › Academic › peer-review

  • Integrative Transkingdom Analysis of the Gut Microbiome in Antibiotic Perturbation and Critical Illness

    Haak, B. W., Argelaguet, R., Kinsella, C. M., Kullberg, R. F. J., Lankelma, J. M., Deijs, M., Klein, M., Jebbink, M. F., Hugenholtz, F., Kostidis, S., Giera, M., Hakvoort, T. B. M., de Jonge, W. J., Schultz, M. J., van Gool, T., van der Poll, T., de Vos, W. M., van der Hoek, L. M. & Wiersinga, W. J., 16 Mar 2021, In: mSystems. 6, 2, e01148-20.

    Research output: Contribution to journal › Article › Academic › peer-review

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    34 Citations (Scopus)

  • Intestinal wound healing: Modulation by enteric and mesenteric factors

    van der Meer, J. H. M., 2021, 199 p.

    Research output: PhD Thesis › Phd-Thesis - Research and graduation internal

    Open Access

  • Kinetic mechanisms by which nickel alters the calcium (Ca2+) transport in intact rat liver

    Utsunomiya, K. S., da Silva, L. J., Iwamoto, J., Constantin, R. P., Gilglioni, E. H., Constantin, J., Bracht, A., Elferink, R. P. J. O. & Ishii-Iwamoto, E. L., Sept 2021, In: Journal of biological inorganic chemistry : JBIC. 26, 6, p. 641-658 18 p.

    Research output: Contribution to journal › Article › Academic › peer-review

    2 Citations (Scopus)

  • Kinome-wide analysis of the effect of statins in colorectal cancer

    Ouahoud, S., Jacobs, R. J., Peppelenbosch, M. P., Fühler, G. M., Heijmans, J., Diks, S., Wildenberg, M. E., Hawinkels, L. J. A. C., Kodach, L. L., Voorneveld, P. W. & Hardwick, J. C. H., 8 Jun 2021, In: British journal of cancer. 124, 12, p. 1978-1987 10 p.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    11 Citations (Scopus)

  • Lipids | Bile salts

    de Buy Wenniger, L. M., Pusl, T. & Beuers, U., 29 Jul 2021, Encyclopedia of Biological Chemistry: Third Edition. Elsevier, Vol. 2. p. 739-743 5 p. (Encyclopedia of Biological Chemistry: Third Edition).

    Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

  • Long-term effects of biliverdin reductase a deficiency in ugt1−/− mice: impact on redox status and metabolism

    Bortolussi, G., Shi, X., Bloemendaal, L. T., Banerjee, B., de Waart, D. R., Baj, G., Chen, W., Oude Elferink, R. P., Beuers, U., Paulusma, C. C., Stocker, R., Muro, A. F. & Bosma, P. J., 1 Dec 2021, In: Antioxidants. 10, 12, 2029.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    5 Citations (Scopus)

  • Low efficacy of recombinant SV40 in Ugt1a1-/- mice with severe inherited hyperbilirubinemia

    Shi, X., Bortolussi, G., ten Bloemendaal, L., Duijst, S., Muro, A. F. & Bosma, P. J., 1 Apr 2021, In: PLOS ONE. 16, 4 April, e0250605.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access

  • Management of primary sclerosing cholangitis and its complications: an algorithmic approach

    Prokopič, M. & Beuers, U., Feb 2021, In: Hepatology international. 15, 1, p. 6-20 15 p.

    Research output: Contribution to journal › Review article › Professional

    Open Access
    21 Citations (Scopus)

  • Molecular regulation of the hepatic bile acid uptake transporter and HBV entry receptor NTCP

    Appelman, M. D., Wettengel, J. M., Protzer, U., Oude Elferink, R. P. J. & van de Graaf, S. F. J., 1 Aug 2021, In: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. 1866, 8, 158960.

    Research output: Contribution to journal › Review article › Academic › peer-review

    Open Access
    23 Citations (Scopus)

  • Monocyte TREM-1 Levels Associate With Anti-TNF Responsiveness in IBD Through Autophagy and Fcγ-Receptor Signaling Pathways

    Prins, M. M., Verstockt, B., Ferrante, M., Vermeire, S. V., Wildenberg, M. E. & Koelink, P. J., 15 Mar 2021, In: Frontiers in immunology. 12, 627535.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    17 Citations (Scopus)

  • Morphometric analysis of the splenic artery using contrast-enhanced computed tomography (CT)

    Brinkman, D. J., Troquay, S., de Jonge, W. J., Irwin, E. D., Vervoordeldonk, M. J., Luyer, M. D. P. & Nederend, J., Mar 2021, In: Surgical and Radiologic Anatomy. 43, 3, p. 377-384 8 p.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    6 Citations (Scopus)

  • Neuronal innervation of the intestinal crypt

    Ten Hove, A. S., Seppen, J. & de Jonge, W. J., 2021, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 320, 2, p. G193-G205

    Research output: Contribution to journal › Review article › Academic › peer-review

    9 Citations (Scopus)

  • New avenues in gene therapy for inherited liver disease

    Shi, X., 2021, 182 p.

    Research output: PhD Thesis › Phd-Thesis - Research and graduation internal

    Open Access

  • Novel classification for adverse events in GI endoscopy: the AGREE classification

    Nass, K. J., Zwager, L. W., van der Vlugt, M., Dekker, E., Bossuyt, P. M. M., Ravindran, S., Thomas-Gibson, S. & Fockens, P., 8 Dec 2021, (E-pub ahead of print) In: Gastrointestinal Endoscopy.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    70 Citations (Scopus)

  • Novel Insights Into Rheumatoid Arthritis Through Characterization of Concordant Changes in DNA Methylation and Gene Expression in Synovial Biopsies of Patients With Differing Numbers of Swollen Joints

    Li Yim, A. Y. F., Ferrero, E., Maratou, K., Lewis, H. D., Royal, G., Tough, D. F., Larminie, C., Mannens, M. M. A. M., Henneman, P., de Jonge, W. J., van de Sande, M. G. H., Gerlag, D. M., Prinjha, R. K. & Tak, P. P., 22 Apr 2021, In: Frontiers in immunology. 12, 651475.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    6 Citations (Scopus)

  • Nutritional therapy strategies in pediatric Crohn’s disease

    Verburgt, C. M., Ghiboub, M., Benninga, M. A., de Jonge, W. J. & van Limbergen, J. E., 1 Jan 2021, In: NUTRIENTS. 13, 1, p. 1-20 20 p., 212.

    Research output: Contribution to journal › Review article › Academic › peer-review

    Open Access
    25 Citations (Scopus)

  • On the Mechanisms of Biliary Flux

    Vartak, N., Drasdo, D., Geisler, F., Itoh, T., P.J.Oude Elferink, R., van de Graaf, S. F. J., Chiang, J., Keitel, V., Trauner, M., Jansen, P. & Hengstler, J. G., Dec 2021, In: Hepatology. 74, 6, p. 3497-3512 16 p.

    Research output: Contribution to journal › Review article › Academic › peer-review

    Open Access
    10 Citations (Scopus)

  • OTC intron 4 variations mediate pathogenic splicing patterns caused by the c.386G>A mutation in humans and spfash mice, and govern susceptibility to RNA-based therapies

    Sacchetto, C., Peretto, L., Baralle, F., Maestri, I., Tassi, F., Bernardi, F., van de Graaf, S. F. J., Pagani, F., Pinotti, M. & Balestra, D., 1 Dec 2021, In: Molecular medicine (Cambridge, Mass.). 27, 1, 157.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    2 Citations (Scopus)

  • Overexpression of transmembrane TNF drives development of ectopic lymphoid structures in the bone marrow and B cell lineage alterations in experimental spondyloarthritis

    Kaaij, M. H., Rip, J., Jeucken, K. C. M., Kan, Y. Y., van Rooijen, C. C. N., Saris, J., Pots, D., Frey, S., Grootjans, J., Schett, G., van Duivenvoorde, L. M., Nolte, M. A., Hendriks, R. W., Corneth, O. B. J., van Hamburg, J. P., Baeten, D. L. P. & Tas, S. W., 1 Nov 2021, In: Journal of immunology (Baltimore, Md.. 207, 9, p. 2337-2346 10 p.

    Research output: Contribution to journal › Article › Academic › peer-review

    3 Citations (Scopus)

  • Recursive ensemble feature selection provides a robust mRNA expression signature for myalgic encephalomyelitis/chronic fatigue syndrome

    Metselaar, P. I., Mendoza-Maldonado, L., Li Yim, A. Y. F., Abarkan, I., Henneman, P., te Velde, A. A., Schönhuth, A., Bosch, J. A., Kraneveld, A. D. & Lopez-Rincon, A., 1 Dec 2021, In: Scientific reports. 11, 1, 11 p., 4541.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    14 Citations (Scopus)

  • Reduced spontaneous itch in mouse models of cholestasis

    Langedijk, J., Bolier, R., Tolenaars, D., ten Bloemendaal, L., Duijst, S., de Waart, D., Beuers, U., Bosma, P. & Elferink, R. O., 1 Dec 2021, In: Scientific reports. 11, 1, 6127.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    6 Citations (Scopus)