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Article
5-Fluorouracil/ leucovorin-induced inhibition of thymidylate synthase in normal tissues of mouse and man
van der Wilt, C. L., van Groeningen, C. J., Pinedo, H. M., Smid, K., Hoekman, K., Meijer, S. & Peters, G. J., 1997, In: Journal of Cancer Research and Clinical Oncology. 123, p. 595-601Research output: Contribution to journal › Article › Academic › peer-review
Open Access11 Citations (Scopus) -
5-Fluorouracil incorporation into RNA and DNA in relation to thymidylate synthase inhibition of human colorectal cancers.
Noordhuis, P., Holwerda, U., van der Wilt, C. L., van Groeningen, C. J., Smid, K., Meijer, S., Pinedo, H. M. & Peters, G. J., 2004, In: Annals of Oncology. 15, 7, p. 1025-32Research output: Contribution to journal › Article › Academic › peer-review
208 Citations (Scopus) -
5-Fluorouracil induced Fas upregulation associated with apoptosis in liver metastases of colorectal cancer patients
Backus, H. H. J., Dukers, D. F., Van Groeningen, C. J., Vos, W., Bloemena, E., Wouters, D., Van Riel, J. M. G. H., Smid, K., Giaccone, G., Pinedo, H. M. & Peters, G. J., 2001, In: Annals of Oncology. 12, 2, p. 209-216 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access61 Citations (Scopus) -
5-FU-induced peripheral neuropathy: a rare complication of a well-known drug
van Laarhoven, H. W. M., Verstappen, C. C. P., Beex, L. V. A. M., Kappelle, A. C. & Punt, C. J. A., 2003, In: Anticancer research. 23, 1B, p. 647-648Research output: Contribution to journal › Article › Academic › peer-review
12 Citations (Scopus) -
5-HT(1A) receptor sensitivity in 5-HT(1B) receptor KO mice is unaffected by chronic fluvoxamine treatment
Vinkers, C. H., Groenink, L., Pattij, T., Olivier, B. & Bouwknecht, J. A., 30 Sept 2011, In: European journal of pharmacology. 667, 1-3, p. 250-257 8 p.Research output: Contribution to journal › Article › Academic › peer-review
4 Citations (Scopus) -
5-HT1A receptor blockade reverses GABA(A) receptor alpha3 subunit-mediated anxiolytic effects on stress-induced hyperthermia
Vinkers, C. H., van Oorschot, R., Korte, S. M., Olivier, B. & Groenink, L., Aug 2010, In: Psychopharmacology. 211, 2, p. 123-30 8 p.Research output: Contribution to journal › Article › Academic › peer-review
14 Citations (Scopus) -
5-HT1A receptor knockout mice and mice overexpressing corticotropin-releasing hormone in models of anxiety
Groenink, L., Pattij, T., De Jongh, R., Van Der Gugten, J., Oosting, R. S., Dirks, A. & Olivier, B., 28 Feb 2003, In: European journal of pharmacology. 463, 1-3, p. 185-197 13 p.Research output: Contribution to journal › Article › Academic › peer-review
88 Citations (Scopus) -
5-HT1B receptor knockout, but not 5-HT1A receptor knockout mice, show reduced startle reactivity and footshock-induced sensitization, as measured with the acoustic startle response
Dirks, A., Pattij, T., Adriaan Bouwknecht, J., Westphal, T. T., Hijzen, T. H., Groenink, L., Van der Gugten, J., Oosting, R. S., Hen, R., Geyer, M. A. & Olivier, B., 29 Jan 2001, In: Behavioural Brain Research. 118, 2, p. 169-178 10 p.Research output: Contribution to journal › Article › Academic › peer-review
39 Citations (Scopus) -
5-HT6 antagonism attenuates cue-induced relapse to cocaine seeking without affecting cocaine reinforcement
Gaalen, M. M., Schetters, D., Schoffelmeer, A. N. M. & de Vries, T. J., 2010, In: International Journal of Neuropsychopharmacology. 13, 7, p. 961-965Research output: Contribution to journal › Article › Academic › peer-review
Open Access20 Citations (Scopus) -
5-Lipoxygenase activating protein (ALOX5AP) gene variants associate with the presence of xanthomas in familial hypercholesterolemia
Oosterveer, D. M., Versmissen, J., Yazdanpanah, M., van der Net, J. B., Defesche, J. C., Kastelein, J. J. P. & Sijbrands, E. J. G., 2009, In: Atherosclerosis. 206, 1, p. 223-227Research output: Contribution to journal › Article › Academic › peer-review
15 Citations (Scopus) -
5-methyltetrahydrofolate, the active form of folic acid, restores endothelial function in familial hypercholesterolemia
Verhaar, M. C., Wever, R. M., Kastelein, J. J., van Dam, T., Koomans, H. A. & Rabelink, T. J., 1998, In: Circulation. 97, 3, p. 237-241Research output: Contribution to journal › Article › Academic › peer-review
339 Citations (Scopus) -
5'-nucleotidase cN-II emerges as a new predictive biomarker of response to gemcitabine/platinum combination chemotherapy in non-small cell lung cancer
Toffalorio, F., Santarpia, M., Radice, D., Jaramillo, C. A., Spitaleri, G., Manzotti, M., Catania, C., Jordheim, L. P., Pelosi, G., Peters, G. J., Tibaldi, C., Funel, N., Spaggiari, L., de Braud, F., de Pas, T. & Giovannetti, E., 2018, In: Oncotarget. 9, 23, p. 16437-16450 14 p.Research output: Contribution to journal › Article › Academic › peer-review
13 Citations (Scopus) -
5-Oxoproline as a cause of high anion gap metabolic acidosis: an uncommon cause with common risk factors
Kortmann, W., van Agtmael, M. A., van Diessen, J., Kanen, B. L., Jakobs, C. A. J. M. & Nanayakkara, P. W. B., 2008, In: Netherlands journal of medicine. 66, 8, p. 354-357Research output: Contribution to journal › Article › Academic › peer-review
31 Citations (Scopus) -
5p13 microduplication in a malformed fetus and his unaffected father
Kariminejad, A., Ghaderi-Sohi, S., Gholami, S., Najafi, K., Kariminejad, R. & Hennekam, R. C. M., Feb 2023, In: American journal of medical genetics. Part A. 191, 2, p. 370-377 8 p.Research output: Contribution to journal › Article › Academic › peer-review
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5q11.2 deletion syndrome revisited-Further narrowing of the smallest region of overlap for the main clinical characteristics of the syndrome
Bayat, A., Bayat, M., Broers, C., Polstra, A. M., Zwijnenburg, P. J. G. & Hjortshøj, T. D., Dec 2021, In: American Journal of Medical Genetics Part A. 185, 12, p. 3844-3850 7 p.Research output: Contribution to journal › Article › Academic › peer-review
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5q35 duplication syndrome: Narrowing the critical region on the distal side and further evidence of intrafamilial variability and expression
van der Lugt, N. M., Weerts, M. J. A., Veenma, D. C. M., Lincke, C. R., Gischler, S. J., Alders, M. & van Ierland, Y., 2022, (E-pub ahead of print) In: American journal of medical genetics. Part A.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
5th Anniversary meeting of the European Research Network Pharmacogenetics/Pharmacogenomics. 8-9 December 2011, Utrecht, The Netherlands
Fox, J. C., Daly, A., Cascorbi, I., Alfirevic, A., Linden, H. & Maitland-van der Zee, A-H., 2012, In: Pharmacogenomics. 13, 7, p. 747-749Research output: Contribution to journal › Article › Academic › peer-review
2 Citations (Scopus) -
5th International Workshop on CMV and Immunosenescence: a shadow of cytomegalovirus infection on immunological memory
Arens, R., Remmerswaal, E. B. M., Bosch, J. A. & van Lier, R. A. W., Apr 2015, In: European journal of immunology. 45, 4, p. 954-957Research output: Contribution to journal › Article › Academic › peer-review
23 Citations (Scopus) -
5-Year Clinical Outcomes in the ICTUS (Invasive versus Conservative Treatment in Unstable coronary Syndromes) Trial A Randomized Comparison of an Early Invasive Versus Selective Invasive Management in Patients With Non-ST-Elevation Acute Coronary Syndrome
Damman, P., Hirsch, A., Windhausen, F., Tijssen, J. G. P. & de Winter, R. J., 2010, In: Journal of the American College of Cardiology. 55, 9, p. 858-864Research output: Contribution to journal › Article › Academic › peer-review
116 Citations (Scopus) -
5-Year Follow-Up After Primary Percutaneous Coronary Intervention With a Paclitaxel-Eluting Stent Versus a Bare-Metal Stent in Acute ST-Segment Elevation Myocardial Infarction A Follow-Up Study of the PASSION (Paclitaxel-Eluting Versus Conventional Stent in Myocardial Infarction With ST-Segment Elevation) Trial
Vink, M. A., Dirksen, M. T., Suttorp, M. J., Tijssen, J. G. P., van Etten, J., Patterson, M. S., Slagboom, T., Kiemeneij, F. & Laarman, G. J., 2011, In: JACC. Cardiovascular interventions. 4, 1, p. 24-29Research output: Contribution to journal › Article › Academic › peer-review
115 Citations (Scopus) -
5-year follow-up of coronary revascularization in diabetic patients with multivessel coronary artery disease: Insights from ARTS (Arterial revascularization therapy study)-II and ARTS-I trials
Onuma, Y., Wykrzykowska, J. J., Garg, S., Vranckx, P. & Serruys, P. W., Mar 2011, In: JACC. Cardiovascular interventions. 4, 3, p. 317-323Research output: Contribution to journal › Article › Academic › peer-review
Open Access60 Citations (Scopus) -
5-year serial follow-up of clinical condition and ventricular function in patients after repair of tetralogy of Fallot
Luijnenburg, S. E., Helbing, W. A., Moelker, A., Kroft, L. J. M., Groenink, M., Roos-Hesselink, J. W., de Rijke, Y. B., Hazekamp, M. G., Bogers, A. J. J. C., Vliegen, H. W. & Mulder, B. J. M., 2013, In: International journal of cardiology. 169, 6, p. 439-444Research output: Contribution to journal › Article › Academic › peer-review
26 Citations (Scopus) -
5-year survival and clinical prognostic factors in progressive supratentorial diffuse "low-grade" astrocytoma: a retrospective analysis of 46 cases
Schuurman, P. R., Troost, D., Verbeeten, B. & Bosch, D. A., 1997, In: Acta neurochirurgica. 139, 1, p. 2-7Research output: Contribution to journal › Article › Academic › peer-review
27 Citations (Scopus) -
61jährige Patientin mit Diabetes mellitus, Gewichtsverlust, Ubelkeit und Erbrechen nach Resektion eines Pankreastumors
SCHRAUDOLPH, M., RICHTER, W. O., Permanetter, W., RITTER, M. M., Beuers, U. & SCHWANDT, P., 1991, In: Internist. 32, 4, p. 229-234Research output: Contribution to journal › Article › Academic › peer-review
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61jähriger Patient mit seit 15 Monaten zunehmenden diffusen Abdominalschmerzen
Beuers, U., Kruis, W., DRASCH, G. A., JACOB, K., Pape, G. R. & Paumgartner, G., 1988, In: Internist. 29, 9, p. 648-650Research output: Contribution to journal › Article › Academic › peer-review
1 Citation (Scopus) -
64Cu-Labeled Phosphonate Cross-Bridged Chelator Conjugates of c(RGDyK) for PET/CT Imaging of Osteolytic Bone Metastases
Ocak, M., Beaino, W., White, A., Zeng, D., Cai, Z. & Anderson, C. J., 1 Mar 2018, In: Cancer Biotherapy and Radiopharmaceuticals. 33, 2, p. 74-83 10 p.Research output: Contribution to journal › Article › Academic › peer-review
8 Citations (Scopus) -
65 jaar wetenschap in H&W: wat heeft de patiënt hieraan?
van Weel, C. & Schellevis, F., 1 Dec 2022, In: Huisarts en wetenschap. 65, 12, p. 32-35 4 p.Translated title of the contribution :65 Years of science in H&W: What does this mean for patients? Research output: Contribution to journal › Article › Professional
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68Ga-DOTATATE PET imaging in clinically non-functioning pituitary macroadenomas
Boertien, T. M., Booij, J., Majoie, C. B. L. M., Drent, M. L., Pereira, A. M., Biermasz, N. R., Simsek, S., Veldman, R. G., Stokkel, M. P. M., Bisschop, P. H., Fliers, E. & N.R., B., 1 Dec 2020, In: european journal of hybrid imaging. 4, 1, 7 p., 4.Research output: Contribution to journal › Article › Academic › peer-review
Open Access5 Citations (Scopus) -
68Ga-PSMA-PET/CT in addition to mpMRI in men undergoing biopsy during active surveillance for low- to intermediate-risk prostate cancer: study protocol for a prospective cross-sectional study
Gondoputro, W., Doan, P., Katelaris, A., Scheltema, M. J., Geboers, B., Agrawal, S., Liu, Z., Yaxley, J., Savdie, R., Rasiah, K., Frydenberg, M., Roberts, M. J., Malouf, D., Wong, D., Shnier, R., Delprado, W., Emmett, L., Stricker, P. D. & Thompson, J., 1 Oct 2023, In: Translational Andrology and Urology. 12, 10, p. 1598-1606 9 p.Research output: Contribution to journal › Article › Academic › peer-review
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6-mercaptopurine, an agonist of Nur77, reduces progression of pulmonary hypertension by enhancing BMP signalling
Kurakula, K., Sun, X-Q., Happé, C., da Silva Goncalves Bos, D., Szulcek, R., Schalij, I., Wiesmeijer, K., Lodder, K., Tu, L., Guignabert, C., de Vries, C. J., de Man, F., Noordegraaf, A. V., Ten Dijke, P., Goumans, M-J. & Bogaard, H. J., 2019, In: The European Respiratory Journal.Research output: Contribution to journal › Article › Academic › peer-review
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6-Mercaptopurine Inhibits Atherosclerosis in Apolipoprotein E*3-Leiden Transgenic Mice Through Atheroprotective Actions on Monocytes and Macrophages
Pols, T. W. H., Bonta, P. I., Pires, N. M. M., Otermin, I., Vos, M., de Vries, M. R., van Eijk, M., Roelofsen, J., Havekes, L. M., Quax, P. H. A., van Kuilenburg, A. B. P., de Waard, V., Pannekoek, H. & de Vries, C. J. M., 2010, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 30, 8, p. 1591-1597Research output: Contribution to journal › Article › Academic › peer-review
31 Citations (Scopus) -
6-Mercaptopurine reduces cytokine and Muc5ac expression involving inhibition of NFκB activation in airway epithelial cells
Kurakula, K., Hamers, A. A., van Loenen, P. & de Vries, C. J. M., 19 Jun 2015, In: Respiratory research. 16, 1, p. 73 73.Research output: Contribution to journal › Article › Academic › peer-review
Open Access27 Citations (Scopus) -
6-Mercaptopurine reduces macrophage activation and gut epithelium proliferation through inhibition of GTPase Rac1
Marinković, G., Hamers, A. A. J., de Vries, C. J. M. & de Waard, V., 2014, In: Inflammatory Bowel Diseases. 20, 9, p. 1487-1495Research output: Contribution to journal › Article › Academic › peer-review
42 Citations (Scopus) -
6-methylmercaptopurine-induced leukocytopenia during thiopurine therapy in inflammatory bowel disease patients
Meijer, B., Kreijne, J. E., van Moorsel, S. A. W., Derijks, L. J. J., Bouma, G., Mulder, C. J. J., Wong, D. R., van der Woude, C. J., van Bodegraven, A. A. & de Boer, N. K. H., 1 Jun 2017, In: Journal of Gastroenterology and Hepatology (Australia). 32, 6, p. 1183-1190 8 p.Research output: Contribution to journal › Article › Academic › peer-review
24 Citations (Scopus) -
6 or 3 months of anticoagulant therapy did not differ for treatment failure in patients with DVT, PE, or both
Kamphuisen, P. W., 2007, In: Evidence-based medicine. 12, 5, p. 143Research output: Contribution to journal › Article › Academic › peer-review
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6th International Conference on Children's Bone Health
Bianchi, M. L., Bishop, N. J., Netelenbos, J. C. & Langman, C. B., 2013, In: IBMS BoneKEy. 10, 423.Research output: Contribution to journal › Article › Academic › peer-review
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6th International Immunoglobulin Symposium: Poster presentations
Fernandez-Cruz, E., Kaveri, S. V., Peter, H. H., Durandy, A., Cantoni, N., Quinti, I., Sorensen, R., Bussel, J. B., Danieli, M. G., Winkelmann, A., Bayry, J., Kaesermann, F., Spaeth, P., Helbert, M., Salama, A., van Schaik, I. N., Yuki, N., Käsermann, F. & Späth, P., 2009, In: Clinical and experimental immunology. 158, Suppl. 1, p. 60-67Research output: Contribution to journal › Article › Academic › peer-review
10 Citations (Scopus) -
6th International Symposium and Expert Workshops on Leukemia and Lymphoma. 17-19 March, 2005, Amsterdam, The Netherlands
Kaspers, G. J. L., Jun 2005, In: Expert Review of Anticancer Therapy. 5, 3, p. 415-417 3 p.Research output: Contribution to journal › Article › Academic › peer-review
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6th international symposium on retroviral nucleocapsid
Berkhout, B., Gorelick, R., Summers, M. F., Mély, Y. & Darlix, J-L., 2008, In: Retrovirology. 5, p. 21Research output: Contribution to journal › Article › Academic › peer-review
5 Citations (Scopus) -
6-Thioguanine for Crohn's disease during pregnancy: thiopurine metabolite measurements in both mother and child
De Boer, NK., van Elburg, R. M., Wilhelm, A. J., Remmink, A. J., van Vugt, J. M. G., Mulder, C. J. J., van Bodegraven, A. A. & de Boer, N. K. H., 2005, In: Scandinavian journal of gastroenterology. 40, 11, p. 1374-1377Research output: Contribution to journal › Article › Academic › peer-review
27 Citations (Scopus) -
6-Thioguanine treatment in inflammatory bowel disease: A critical appraisal by a European 6-TG working party
De Boer, N. K. H., Reinisch, W., Teml, A., Van Bodegraven, A. A., Schwab, M., Lukas, M., Ochsenkühn, T., Petritsch, W., Knoflach, P., Almer, S., Van Der Merwe, S. W., Herrlinger, K. R., Seiderer, J., Vogelsang, H. & Mulder, C. J. J., 1 Apr 2006, In: Digestion. 73, 1, p. 25-31 7 p.Research output: Contribution to journal › Article › Academic › peer-review
62 Citations (Scopus) -
6-week radiographs unsuitable for diagnosis of suspected scaphoid fractures
Mallee, W. H., Mellema, J. J., Guitton, T. G., Goslings, J. C., Ring, D. & Doornberg, J. N., 2016, In: Archives of Orthopaedic and Trauma Surgery. 136, 6, p. 771-778Research output: Contribution to journal › Article › Academic › peer-review
23 Citations (Scopus) -
70 JAAR GERONTOLOGIE IN NEDERLAND: Infrastructuur en activiteiten
Deeg, DJH., 2017, In: Tijdschrift voor gerontologie en geriatrie. 48, 5Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
7"Real-World" use of cinacalcet for managing SHPT in different European countries: analysis of data from the ECHO observational study
Vervloet, M. G., Bencova, V., Malberti, F., Ashman, N., Os, I., Saha, H., Urena, P., Zitt, E., Rix, M., Ryba, M., Fouque, D., Dehmel, B., Petavy, F. & Jacobson, S. H., 2010, In: Clinical nephrology. 74, 3, p. 198-208Research output: Contribution to journal › Article › Academic › peer-review
16 Citations (Scopus) -
7ROSES, a transdiagnostic intervention for promoting self-efficacy in traumatized refugees: a first quantitative evaluation
van Heemstra, H. E., Scholte, W. F., Haagen, J. F. G. & Boelen, P. A., 1 Jan 2019, In: European journal of psychotraumatology. 10, 1, 1673062.Translated title of the contribution :7ROSES, a transdiagnostic intervention for promoting self-efficacy in traumatized refugees: una primera evaluación cuantitativa Research output: Contribution to journal › Article › Academic › peer-review
Open Access14 Citations (Scopus) -
7-Tesla Magnetic Resonance Imaging Scanning in Deep Brain Stimulation for Parkinson's Disease: Improving Visualization of the Dorsolateral Subthalamic Nucleus
Verlaat, L., Rijks, N., Dilai, J., Admiraal, M., Beudel, M., de Bie, R. M. A., van der Zwaag, W., Schuurman, R., van den Munckhof, P. & Bot, M., Apr 2024, In: Movement Disorders Clinical Practice. 11, 4, p. 373-380 8 p.Research output: Contribution to journal › Article › Academic › peer-review
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7 tesla T2*-weighted MRI as a tool to improve detection of focal cortical dysplasia 7 tesla T2*-weighted MRI as a tool to improve detection of focal cortical dysplasia
Veersema, T. J., van Eijsden, P., Gosselaar, P. H., Hendrikse, J., Zwanenburg, J. J. M., Spliet, W. G. M., Aronica, E., Braun, K. P. J. & Ferrier, C. H., 2016, In: Epileptic Disorders. 18, 3, p. 315-323Research output: Contribution to journal › Article › Academic › peer-review
28 Citations (Scopus) -
7T MRI allows detection of disturbed cortical lamination of the medial temporal lobe in patients with Alzheimer's disease
Kenkhuis, B., Jonkman, L. E., Bulk, M., Buijs, M., Boon, B. D. C., Bouwman, F. H., Geurts, J. J. G., van de Berg, W. D. J. & van der Weerd, L., 1 Jan 2019, In: NeuroImage: Clinical. 21, 1 p., 101665.Research output: Contribution to journal › Article › Academic › peer-review
Open Access24 Citations (Scopus) -
7T T-2*-weighted magnetic resonance imaging reveals cortical phase differences between early- and late-onset Alzheimer's disease
van Rooden, S., Doan, N. T., Versluis, M. J., Goos, J. D. C., Webb, A. G., Oleksik, A. M., van der Flier, W. M., Scheltens, P., Barkhof, F., Weverlinge-Rynsburger, A. W. E., Blauw, G. J., Reiber, J. H. C., van Buchem, M. A., Milles, J. & van der Grond, J., 2015, In: Neurobiology of aging. 36, 1, p. 20-26Research output: Contribution to journal › Article › Academic › peer-review
41 Citations (Scopus) -
7T versus 3T MR Angiography to Assess Unruptured Intracranial Aneurysms
Leemans, E., Cornelissen, B., Sing, M. L. C., Sprengers, M., van den Berg, R., Roos, Y., Vandertop, W. P., Slump, C., Marquering, H. & Majoie, C., 1 Nov 2020, In: Journal of neuroimaging. 30, 6, p. 779-785 7 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access2 Citations (Scopus)